Intermediate filaments control collective migration by restricting traction forces and sustaining cell–cell contacts

Autor: Sandrine Etienne-Manneville, Nicolas Borghi, Mithila Burute, Shailaja Seetharaman, Chiara De Pascalis, Xavier Trepat, Batiste Boëda, Carlos Pérez-González, Cécile Leduc, Benoit Vianay

Publikováno v: The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (9), pp.3031-3044. ⟨10.1083/jcb.201801162⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Cell Biology 9 (217), 3031-3044. (2018)
Journal of Cell Biology, 2018, 217 (9), pp.3031-3044. ⟨10.1083/jcb.201801162⟩

Using an in vitro wound healing assay, De Pascalis et al. show that intermediate filaments (IFs) participate in the dynamics of the acto-myosin network and its association with adhesions in astrocytes during collective migration. Glial IFs control th

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http://europepmc.org/articles/PMC6122997