Zobrazeno 1 - 10
of 171
pro vyhledávání: '"ficolin-2"'
Autor:
Gabriela Gajek, Anna S. Świerzko, Dariusz Jarych, Damian Mikulski, Paulina Kobiela, Karolina Chojnacka, Maja Kufelnicka-Babout, Agnieszka Szala-Poździej, Jędrzej Chrzanowski, Katarzyna Sobczuk, Wojciech Fendler, Misao Matsushita, Iwona Domżalska-Popadiuk, Jan Mazela, Jarosław Kalinka, Hideharu Sekine, Maciej Cedzyński
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionFicolin-2 is a serum pattern recognition molecule, involved in complement activation via the lectin pathway. This study aimed to investigate the association of ficolin-2 concentration in cord blood serum with complications related to prem
Externí odkaz:
https://doaj.org/article/f648a8902bb645bb940744b51a7a2c5c
Autor:
Li-ting Wang, Qiu-ling Zeng, Shao-lan Jiang, Zhen-yu Chen, Xiao-ling Wang, Ling Li, Xiaolong Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveThis study aimed to investigate the role of ficolin-2 (FCN2) in the development and course of hepatocellular carcinoma (HCC) and to contribute to the evolution of innovative HCC therapeutics.MethodsOncomine, GEPIA (Gene Expression Profiling
Externí odkaz:
https://doaj.org/article/5b7e4bdd31dd4365985913f55dbed2f3
Autor:
Severin Vogt, Jörg D. Leuppi, Philipp Schuetz, Beat Mueller, Carmen Volken, Sarah Dräger, Marten Trendelenburg, Jonas Rutishauser, Michael Osthoff
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background The innate and adaptive immune system is involved in the airway inflammation associated with acute exacerbations in patients with chronic obstructive pulmonary disease (COPD). We evaluated the association of mannose-binding lectin
Externí odkaz:
https://doaj.org/article/8e9951d83c7f445c9db5fa54d24f6995
Autor:
Ngo Truong Giang, Hoang Van Tong, Trinh Huu Nghia, Hoang Vu Hung, Do Tuan Anh, Le Van Nam, Can Van Mao, Nguyen Truong Giang, Le Dinh Thanh, Ho Anh Son, Thirumalaisamy P. Velavan, Quyet Do, Nguyen Linh Toan
Publikováno v:
International Journal of Infectious Diseases, Vol 95, Iss , Pp 253-261 (2020)
Background and objective: The human ficolin-2, encoded by FCN2, recognizes pathogen-associated acetylated residues on their cell surfaces and activates the lectin complement cascade. This study aimed to investigate the contribution of human ficolin-2
Externí odkaz:
https://doaj.org/article/dac0ee5def1c4af6a96c99c995265230
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Reports conflict regarding which lectin-microbial ligand interactions elicit a protective response from the lectin pathway (LP) of complement. Using fluorescent microscopy, we demonstrate the human lectin ficolin-2 binds to Streptococcus pneumoniae s
Externí odkaz:
https://doaj.org/article/b82294322a3e495bbbdc1d3b3e49d6e3
Autor:
Anna S. Świerzko, Dariusz Jarych, Gabriela Gajek, Karolina Chojnacka, Paulina Kobiela, Maja Kufelnicka-Babout, Mateusz Michalski, Katarzyna Sobczuk, Agnieszka Szala-Poździej, Misao Matsushita, Jan Mazela, Iwona Domżalska-Popadiuk, David C. Kilpatrick, Jarosław Kalinka, Hideharu Sekine, Maciej Cedzyński
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Ficolin-2 is regarded as an important innate immunity factor endowed with both lectin (carbohydrate recognition) qualities and ability to induce complement activation. The aim of this study was to investigate the association of the FCN2 3’-untransl
Externí odkaz:
https://doaj.org/article/0aa3694819ae4ea8bb98554a02850b12
Autor:
Tomofumi Kobayashi, Koji Kuronuma, Atsushi Saito, Kimiyuki Ikeda, Shigeru Ariki, Atsushi Saitou, Mitsuo Otsuka, Hirofumi Chiba, Satoshi Takahashi, Motoko Takahashi, Hiroki Takahashi
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background The incidence of infectious disease caused by nontuberculous mycobacteria is increasing worldwide. Pulmonary Mycobacterium avium complex (MAC) disease is difficult to treat with chemotherapy, and its mechanism of infection, infect
Externí odkaz:
https://doaj.org/article/a66c24fe017342d9b35f1ce266443009
Autor:
Michael Osthoff, Veronika K. Jaeger, Ingmar A. F. M. Heijnen, Marten Trendelenburg, Suzana Jordan, Oliver Distler, Ulrich A. Walker
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background The role of the complement system in the pathogenesis of systemic sclerosis (SSc) is controversial. This study investigated the role of the lectin pathway of complement as a mediator of ischemia/reperfusion injury in SSc. Methods
Externí odkaz:
https://doaj.org/article/5d280bb03cd84b4884c3e66225c39709
Autor:
Severin Vogt, Marten Trendelenburg, Michael Tamm, Daiana Stolz, Katrin Esther Hostettler, Michael Osthoff
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundThe role of the lectin pathway of complement in the pathogenesis of interstitial lung diseases (ILDs) is largely unknown. Pattern recognition receptors (PRR) of the lectin pathway are involved in the clearance of apoptotic cells either via
Externí odkaz:
https://doaj.org/article/87520a3f1dba42e0b48ec83a6045246f
Autor:
Camilla Adler Sørensen, Anne Rosbjerg, Betina Hebbelstrup Jensen, Karen Angeliki Krogfelt, Peter Garred
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Enteroaggregative Escherichia coli (EAEC) causes acute and persistent diarrhea worldwide. Still, the involvement of host factors in EAEC infections is unresolved. Binding of recognition molecules from the lectin pathway of complement to EAEC strains
Externí odkaz:
https://doaj.org/article/9ec1859663bb4d1089c3cb895ea1edd5