Zobrazeno 1 - 10
of 202
pro vyhledávání: '"fibrotic diseases"'
Autor:
José Alvaro Lomelí-Nieto, José Francisco Muñoz-Valle, José Eduardo Navarro-Zarza, Christian Johana Baños-Hernández, Jesús Alberto Gutierrez-Brito, Valeria Renteria-Cabrera, Eduardo Arturo Horta-Chávez, José Javier Morales-Núñez, Samuel García-Arellano, Isela Parra-Rojas, Jorge Hernández-Bello
Publikováno v:
Life, Vol 14, Iss 9, p 1056 (2024)
Systemic sclerosis (SSc) is characterized by a complex interplay of vascular damage, inflammation, and fibrosis, affecting the skin and internal organs. Plasminogen activator inhibitor-1 (PAI-1), a protein encoded by the SERPINE1 gene, is a potential
Externí odkaz:
https://doaj.org/article/7fd67229e1a5410790f04707fe1be265
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 2, Pp 301-305 (2023)
Epithelial-mesenchymal transition (EMT) is a process by which epithelial cells undergo morphological changes to gain a mesenchymal cell phenotype and migratory properties. As a class of negative regulators of RhoGTPases, RhoGTPase activating proteins
Externí odkaz:
https://doaj.org/article/dc696e17e2be4a699d97c60cd9fd5048
Publikováno v:
Genes and Diseases, Vol 9, Iss 6, Pp 1493-1505 (2022)
Annexin A1, a well-known endogenous anti-inflammatory mediator, plays a critical role in a variety of pathological processes. Fibrosis is described by a failure of tissue regeneration and contributes to the development of many diseases. Accumulating
Externí odkaz:
https://doaj.org/article/754ad466eeba444298f68d4a9fc399d4
Akademický článek
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Akademický článek
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Autor:
Guangxin Peng, Xiaoling Tang, Yang Gui, Jing Yang, Lifang Ye, Liuyang Wu, Ya hui Ding, Lihong Wang
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The transient receptor potential vanilloid subtype 1 (TRPV1), belonging to the TRPV channel family, is a non-selective, calcium-dependent, cation channel implicated in several pathophysiological processes. Collagen, an extracellular matrix component,
Externí odkaz:
https://doaj.org/article/a45a01cecef54bf883716514241ba585
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 2051-2061 (2021)
Fibrotic diseases pose significant clinical challenges due to their broadness and complexity. Thus, a better understanding of fibrogenesis and the development of more effective treatments is imperative. Recent evidence suggests a significant antifibr
Externí odkaz:
https://doaj.org/article/69448be7d6764c69a6f2ef08326091a9
Publikováno v:
Autoimmunity, Vol 53, Iss 1, Pp 1-7 (2020)
Fibrosis is characterised by excessive deposition of the extracellular matrix (ECM) and develops because of fibroblast differentiation during the process of inflammation. There are few effective treatment options for this diseases due to the aetiolog
Externí odkaz:
https://doaj.org/article/7390f1d25cdb4767a8b5b53015c3042e
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Acute and chronic inflammation often leads to fibrosis, which is also the common and final pathological outcome of chronic inflammatory diseases. To explore the common genes and pathogenic pathways among different fibrotic diseases, we collected all
Externí odkaz:
https://doaj.org/article/8e2f5219140940ce843dee27daa45a5c
Autor:
Mengjuan Zhang, Song Zhang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Fibrosis is the extensive deposition of fibrous connective tissue, and it is characterized by the accumulation of collagen and other extracellular matrix (ECM) components. Fibrosis is essential for wound healing and tissue repair in response to a var
Externí odkaz:
https://doaj.org/article/4e3c7946027c425ab1da757ff56489b5