Zobrazeno 1 - 10
of 97
pro vyhledávání: '"fibroblast growth factor receptor 1 (fgfr1)"'
Autor:
Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract The endothelial glycocalyx, located at the luminal surface of the endothelium, plays an important role in the regulation of leukocyte adhesion, vascular permeability, and vascular homeostasis. Endomucin (EMCN), a component of the endothelial
Externí odkaz:
https://doaj.org/article/f866f4dfaaaf46d7b2fa5d0f1a92f343
Autor:
Zhang Weilin, Huang Zhongcheng, Xiao Zhigang, Wang Hui, Liao Qianchao, Deng Zhengru, Wu Deqing, Wang Junjiang, Li Yong
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 1819-1832 (2023)
Despite substantial advancements in screening, surgery, and chemotherapy, colorectal cancer remains the second most lethal form of the disease. Nuclear factor kappa B (NF-κB) signaling is a critical driver facilitating the malignant transformation o
Externí odkaz:
https://doaj.org/article/f536b42e31154a1f830210810953f38e
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 5, Pp 733-738 (2023)
Objective To investigate whether multiple gene mutations were existed to cause congenital hypogonadotropic hypogonadism(CHH), by screening genes in CHH patients with FGFR1 mutations. Methods FGFR1 mutations were identified in 15 CHH patients. Other C
Externí odkaz:
https://doaj.org/article/4b125e72c2ed4cccb1fa029dfbfc160e
Akademický článek
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Autor:
Tian Jiang, Weiping Hu, Shaoyuan Zhang, Changhao Ren, Siyun Lin, Zhenyu Zhou, Hao Wu, Jun Yin, Lijie Tan
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-15 (2022)
Highlights It is the first time to prove the confirm the endothelial glycocalyx impairment in COPD. FGF10 attenuates the development of emphysema and the shedding of glycocalyx induced by CSE in vivo. FGF10 alleviates smoke-induced endothelial apopto
Externí odkaz:
https://doaj.org/article/db0a8238d60448f8b8c3ce2b1b57652a
Akademický článek
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Autor:
Belhadj Amina, Addou Klouche Lynda, Seddiki Sonia, Belhadj Adel, Benammar H Jelloul, Medjamia Miloud, Sahraoui Tewfik
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 64, Iss 2, Pp 254-260 (2021)
Context: Breast cancer is the most common cause of cancer mortality among women worldwide. It is a heterogeneous disease partly responsible for treatment failure in luminal B patients. Deregulation of fibroblast growth factor signaling has been found
Externí odkaz:
https://doaj.org/article/aeaf37edaa924238a7b69cdfcddbf41d
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background The gene encoding fibroblast growth factor receptor 1 (FGFR1) is emerging as a therapeutic and prognostic biomarker in various cancer types, including head and neck squamous cell carcinoma (SCC). Here, we investigated the clinicop
Externí odkaz:
https://doaj.org/article/461aa8b888d54dda8a8a0e4e1a194291
Akademický článek
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Publikováno v:
Aging (Albany NY)
Background Most recently, long non-coding RNAs (lncRNAs) emerge as crucial modulators in many biological processes, such as embryonic development, cell growth, and tumorigenesis. However, the correlations between lncRNAs and colorectal cancer (CRC) c