Fibro-adipogenic progenitor cells in skeletal muscle unloading: metabolic and functional impairments

Autor: Margarita Sorokina, Danila Bobkov, Natalia Khromova, Natalia Vilchinskaya, Boris Shenkman, Anna Kostareva, Renata Dmitrieva

Publikováno v: Skeletal Muscle, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Background Skeletal muscle resident fibro-adipogenic progenitor cells (FAPs) control skeletal muscle regeneration providing a supportive role for muscle stem cells. Altered FAPs characteristics have been shown for a number of pathological co

Externí odkaz: https://doaj.org/article/17f3b13d73c540d0ba4d20b013f1cead

Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic progenitors

Autor: Osvaldo Contreras, Richard P. Harvey

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, prolifer

Externí odkaz: https://doaj.org/article/3e96b57340f94593aee24ac4f9659fc4

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Muscle resting and TGF-β inhibitor treatment prevent fatty infiltration following skeletal muscle injury

Autor: Pagano, Allan, Arc-Chagnaud , Coralie, Brioche, Thomas, Chopard , Angèle, Py, Guillaume

Publikováno v: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry, Karger, 2019, 53, pp.62-75. ⟨10.33594/000000121⟩
Cellular Physiology and Biochemistry, Vol 53, Iss 1, Pp 62-75 (2019)
Cellular Physiology and Biochemistry (53), 62-75. (2019)

Background/Aims: Skeletal muscle injuries are the most common type of injury occurring in sports, and investigating skeletal muscle regeneration as well as understanding the related processes is an important aspect of the sports medicine field. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fa14bb60475284aec9c8df1a9cb6713a
https://hal.inrae.fr/hal-02617714