Zobrazeno 1 - 10
of 537
pro vyhledávání: '"fibro/adipogenic progenitors"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Fibrosis is a significant pathological feature of chronic skeletal muscle injury, profoundly affecting muscle regeneration. Fibro-adipogenic progenitors (FAPs) have the ability to differentiate into myofibroblasts, acting as a pri
Externí odkaz:
https://doaj.org/article/6e05ad9ce6ce4c6c99523e3a601fef93
Autor:
Congcong Zhang, Guoqi Li, Fan Zhang, Yanhong Zhang, Shiyao Hong, Shijuan Gao, Yan Liu, Jie Du, Yulin Li
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract During the process of muscle regeneration post‐injury in adults, muscle stem cells (MuSCs) function is facilitated by neighboring cells within the pro‐regenerative niche. However, the precise mechanism triggering the initiation of signal
Externí odkaz:
https://doaj.org/article/ca9dd39d221c467d899b1cb25d6d7fe3
Autor:
Chengzhu Zhao, Makoto Ikeya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Fibro/adipogenic progenitors (FAPs) that reside in muscle tissue are crucial for muscular homeostasis and regeneration as they secrete signaling molecules and components of the extracellular matrix. During injury or disease, FAPs differentiate into d
Externí odkaz:
https://doaj.org/article/01dc4e49159d4b23aa69dd8bb338f738
Autor:
Lara Gil-Melgosa, Rafael Llombart-Blanco, Leire Extramiana, Isabel Lacave, Gloria Abizanda, Estibaliz Miranda, Xabier Agirre, Felipe Prósper, Antonio Pineda-Lucena, Juan Pons-Villanueva, Ana Pérez-Ruiz
Publikováno v:
Bone & Joint Research, Vol 13, Iss 4, Pp 169-183 (2024)
Aims: Rotator cuff (RC) injuries are characterized by tendon rupture, muscle atrophy, retraction, and fatty infiltration, which increase injury severity and jeopardize adequate tendon repair. Epigenetic drugs, such as histone deacetylase inhibitors (
Externí odkaz:
https://doaj.org/article/6f1a66f00d414accba4ab27fbadcc1c7
Autor:
Yoshiyuki Takahashi, Masaki Yoda, Osahiko Tsuji, Keisuke Horiuchi, Kota Watanabe, Masaya Nakamura
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background The regenerative and adaptive capacity of skeletal muscles reduces with age, leading to severe disability and frailty in the elderly. Therefore, development of effective therapeutic interventions for muscle wasting is important bo
Externí odkaz:
https://doaj.org/article/59b24e2b49cc46e496dcfa8bcfd552d9
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Cristina Rodríguez, Filipa Timóteo-Ferreira, Gabriella Minchiotti, Silvia Brunelli, Ombretta Guardiola
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Skeletal muscle regeneration relies on the intricate interplay of various cell populations within the muscle niche—an environment crucial for regulating the behavior of muscle stem cells (MuSCs) and ensuring postnatal tissue maintenance and regener
Externí odkaz:
https://doaj.org/article/ce5cb5c49514490d9b7a10629cac9eaa
Autor:
Yuya Takahashi, Hiroki Fujita, Yusuke Seino, Satoko Hattori, Shihomi Hidaka, Tsuyoshi Miyakawa, Atsushi Suzuki, Hironori Waki, Daisuke Yabe, Yutaka Seino, Yuichiro Yamada
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 6, Pp 2703-2718 (2023)
Abstract Background Intramuscular adipose tissue (IMAT) formation derived from muscle fibro‐adipogenic progenitors (FAPs) has been recognized as a pathological feature of sarcopenia. This study aimed to explore whether genetic and pharmacological g
Externí odkaz:
https://doaj.org/article/7b9f6304881048c88a12d2cf1871a207
Autor:
Mengyao Liu, Martin Ng, Tuan Phu, Laura Bouchareychas, Brian T. Feeley, Hubert T. Kim, Robert L. Raffai, Xuhui Liu
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Macrophage polarization has been observed in the process of muscle injuries including rotator cuff (RC) muscle atrophy and fatty infiltration after large tendon tears. In our previous study, we showed that fibrogenesis and white a
Externí odkaz:
https://doaj.org/article/aa31497d10514eaf83e1a96d18afedc5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.