Zobrazeno 1 - 10
of 2 349
pro vyhledávání: '"fibrates"'
Autor:
Finamore, Claudia1, De Marino, Simona1, Cassiano, Chiara1, Napolitano, Giuliano1, Rapacciuolo, Pasquale1, Marchiano, Silvia2, Biagioli, Michele2, Roselli, Rosalinda2, Di Giorgio, Cristina2, Festa, Carmen1 carmen.festa@unina.it, Fiorucci, Stefano2, Zampella, Angela1, Piaz, Fabrizio Dal3, Laghezza, Antonio4
Publikováno v:
Frontiers in Chemistry. 2024, p1-13. 13p.
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 11, Pp 07-10 (2024)
Acute Pancreatitis (AP) is a prevalent and rapidly progressive inflammatory disorder of the pancreas, often presenting with abdominal pain and elevated serum pancreatic enzymes. The present case report emphasises the crucial need for accurately diagn
Externí odkaz:
https://doaj.org/article/06b7e67daaaf4e36b6a91e2898502761
Autor:
Chen, Yiran, Zheng, Kunyu, Da, Gahu, Wang, Xu, Wei, Yi, Wang, Guochun, Zhang, Fengchun, Wang, Li
Publikováno v:
Expert Opinion on Pharmacotherapy; Sep2024, Vol. 25 Issue 13, p1825-1834, 10p
Autor:
Bilal Bashir, Jonathan Schofield, Paul Downie, Michael France, Darren M. Ashcroft, Alison K. Wright, Stefano Romeo, Ioanna Gouni-Berthold, Akhlaq Maan, Paul N. Durrington, Handrean Soran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
AimsHistorically, atherosclerotic cardiovascular disease (ASCVD) risk profile mitigation has had a predominant focus on low density lipoprotein cholesterol (LDL-C). In this narrative review we explore the residual ASCVD risk profile beyond LDL-C with
Externí odkaz:
https://doaj.org/article/c848dfd6eaa84944b4170ee1460c2040
Autor:
Claudia Finamore, Simona De Marino, Chiara Cassiano, Giuliano Napolitano, Pasquale Rapacciuolo, Silvia Marchianò, Michele Biagioli, Rosalinda Roselli, Cristina Di Giorgio, Carmen Festa, Stefano Fiorucci, Angela Zampella
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
BAR502, a bile acid analogue, is active as dual FXR/GPBAR1 agonist and represents a promising lead for the treatment of cholestasis and NASH. In this paper we report the synthesis and the biological evaluation of a library of hybrid compounds prepare
Externí odkaz:
https://doaj.org/article/66a1ede6d3ce454db68ec5a259f39f5f
Autor:
Rajpurohit, Anuja S.1, Punde, Ninad S.1, Rawool, Chaitali R.1, Srivastava, Ashwini K.1 akschbu@yahoo.com
Publikováno v:
Electroanalysis. Mar2018, Vol. 30 Issue 3, p571-582. 12p.
Publikováno v:
Results in Chemistry, Vol 8, Iss , Pp 101608- (2024)
Novel hydrogen sulfide donor-based fibrate derivatives were synthesized and assessed for hypolipidemic and hepatoprotective effects in Triton WR-1339-induced hyperlipidemic mice. After preliminary screening of the target compounds, T5 exhibited signi
Externí odkaz:
https://doaj.org/article/e9f349f3982045ddbd63ea4669fcd777
Autor:
Annalisa Filtz, Siddhant Parihar, Garred S. Greenberg, Christine M. Park, Andrea Scotti, Daniel Lorenzatti, Juan J Badimon, Daniel E. Soffer, Peter P. Toth, Carl J. Lavie, Vera Bittner, Salim S. Virani, Leandro Slipczuk
Publikováno v:
American Journal of Preventive Cardiology, Vol 18, Iss , Pp 100648- (2024)
Triglycerides play a crucial role in the efficient storage of energy in the body. Mild and moderate hypertriglyceridemia (HTG) is a heterogeneous disorder with significant association with atherosclerotic cardiovascular disease (ASCVD), including myo
Externí odkaz:
https://doaj.org/article/bcf115f88e6647648c09b9f22bd05241
Autor:
Bolier, Ruth1 a.r.bolier@amc.uva.nl, de Vries, Elsemieke S.1, Parés, Albert2, Helder, Jeltje1, Marleen Kemper, E.3, Zwinderman, Koos4, Oude Elferink, Ronald P.1, Beuers, Ulrich1, Kemper, E Marleen3 (AUTHOR), Elferink, Ronald P Oude5 (AUTHOR), Netherlands Association for the Study of the Liver (NASL) Cholestatic Liver Diseases Study Group (CORPORATE AUTHOR)
Publikováno v:
Trials. 5/23/2017, Vol. 18, p1-9. 9p. 1 Chart.
Autor:
Filippo Gabrielli, Eleonora Crepaldi, Alessia Cavicchioli, Marco Rivi, Arianna Carmen Costanzo, Carmela Cursaro, Pietro Andreone
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1227 (2024)
Cholestasis is a clinical and laboratory syndrome indicating impaired bile production or excretion. One of the hallmark symptoms of cholestasis is pruritus. Itch can be severe and debilitating for patients, impacting their quality of life similarly t
Externí odkaz:
https://doaj.org/article/c89d1f6f15ba4c3589967ef1b1d34e7a