Zobrazeno 1 - 10
of 335
pro vyhledávání: '"fcγriib"'
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background The role of the scavenger receptor CD36 in cell metabolism and the immune response has been investigated mainly in macrophages, dendritic cells, and T cells. However, its involvement in B cells has not been comprehensively examine
Externí odkaz:
https://doaj.org/article/3c8857677d3d494bb7a2a91c2b71e3d6
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 1, Pp 64-75 (2024)
Background: B cells are essential for providing humoral protection against acute influenza A virus (IAV) infection. FcγRIIB, a regulator of antibody (Ab) production, influences immune responses during pathogen infections, but its specific impact on
Externí odkaz:
https://doaj.org/article/04486bd0b66b486ca3282ab2775994d9
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 41-57 (2024)
YingWen Han,* Luyao Wang,* Xiaokun Ye, Xue Gong, Xiaoyi Shao Department of Immunology, Medical School, Nantong University, Nantong, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoyi
Externí odkaz:
https://doaj.org/article/047ac647bc6e4895a47eb88f5c35d04a
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The rising global incidence of IgE-mediated allergic reactions poses a significant challenge to the quality of life of affected individuals and to healthcare systems, with current treatments being limited in effectiveness, safety, and disease-modifyi
Externí odkaz:
https://doaj.org/article/ba77a043962c47d3991436105c44b29e
Akademický článek
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Akademický článek
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Autor:
Vivian Changying Jiang, Yang Liu, Alexa Jordan, Angela Leeming, Joseph McIntosh, Shengjian Huang, Rongjia Zhang, Qingsong Cai, Zhihong Chen, Yijing Li, Yuxuan Che, Lei Nie, Ingrid Karlsson, Linda Mårtensson, Mathilda Kovacek, Ingrid Teige, Björn Frendéus, Michael Wang
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-7 (2022)
Abstract Inevitable relapses remain as the major therapeutic challenge in patients with mantle cell lymphoma (MCL) despite FDA approval of multiple targeted therapies and immunotherapies. Fc gamma receptors (FcγRs) play important roles in regulating
Externí odkaz:
https://doaj.org/article/9f67a31b108c4b628eddafeb215126c0
Autor:
Khiyam Hussain, Rena Liu, Rosanna C. G. Smith, Kri T. J. Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L. S. Cleary, Robert J. Oldham, Russell B. Foxall, Sonya James, Steven G. Booth, Tom Murray, Lekh N. Dahal, Chantal E. Hargreaves, Robert S. Kemp, Jemma Longley, James Douglas, Hannah Markham, Serena J. Chee, Richard J. Stopforth, Ali Roghanian, Matthew J. Carter, Christian H. Ottensmeier, Bjorn Frendéus, Ramsey I. Cutress, Ruth R. French, Martin J. Glennie, Jonathan C. Strefford, Stephen M. Thirdborough, Stephen A. Beers, Mark S. Cragg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-32 (2022)
Abstract Background Hypoxia is a hallmark of the tumor microenvironment (TME) and in addition to altering metabolism in cancer cells, it transforms tumor-associated stromal cells. Within the tumor stromal cell compartment, tumor-associated macrophage
Externí odkaz:
https://doaj.org/article/4a2581bb496d4f649850cb54190883b9
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Fc gamma receptor IIb (FcγRIIb) is an important inhibitory receptor that plays vital roles in regulating various immune response processes and the pathogenesis of many infectious diseases. The purpose of our research was to evalu
Externí odkaz:
https://doaj.org/article/d6c4e11631fc4c13bd4bc6a971d641f3
Autor:
Yuji Hori, Ken Ohmine, Hitoshi Katada, Yuki Noguchi, Kazuki Sato, Takeru Nambu, Lam Runyi Adeline, Gan Siok Wan, Kenta Haraya, Kazuhisa Ozeki, Masahiko Nanami, Tatsuhiko Tachibana, Zenjiro Sampei, Taichi Kuramochi, Junichi Nezu, Kunihiro Hattori, Tomoyuki Igawa
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
A conventional antibody targeting a soluble antigen in circulation typically requires a huge dosage and frequent intravenous administration to neutralize the antigen. This is because antigen degradation is reduced by the formation of antigen–antibo
Externí odkaz:
https://doaj.org/article/664a7d33da584019aead7576585d2286