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pro vyhledávání: '"fatty aldehyde"'
Akademický článek
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Publikováno v:
Metabolites, Vol 13, Iss 6, p 682 (2023)
Sjögren–Larsson syndrome (SLS) is a rare inherited neurocutaneous disease characterized by ichthyosis, spastic diplegia or tetraplegia, intellectual disability and a distinctive retinopathy. SLS is caused by bi-allelic mutations in ALDH3A2, which
Externí odkaz:
https://doaj.org/article/12052040b59b4af988af169ba38a3328
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 30, Iss , Pp 100839- (2022)
Sjögren-Larsson syndrome (SLS) is a neurocutaneous disease caused by mutations in ALDH3A2 that result in deficient fatty aldehyde dehydrogenase (FALDH) activity and impaired fatty aldehyde and fatty alcohol oxidation. The pathogenesis of SLS is thou
Externí odkaz:
https://doaj.org/article/d3b8a41fe9b441cf983ce1fa3e5bf914
Akademický článek
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Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-10 (2018)
Abstract Background Fatty aldehydes are industrially relevant compounds, which also represent a common metabolic intermediate in the microbial synthesis of various oleochemicals, including alkanes, fatty alcohols and wax esters. The key enzymes in bi
Externí odkaz:
https://doaj.org/article/48173f925e0d42ba9eef875d3f0efa23
Autor:
Fabian Schumacher, Corinna Neuber, Hannah Finke, Kai Nieschalke, Jessica Baesler, Erich Gulbins, Burkhard Kleuser
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 8, Pp 1648-1660 (2017)
Sphingosine 1-phosphate (S1P), a bioactive lipid involved in various physiological processes such as cell proliferation and apoptosis, can be irreversibly cleaved by S1P lyase, yielding phosphoethanolamine and (2E)-hexadecenal (2EHD). The latter meta
Externí odkaz:
https://doaj.org/article/ce2916f0b9a947108b8c5b69e9681677
Autor:
Christopher J. McLean, Jon Marles-Wright, Rafael Custodio, Jonathan Lowther, Amanda J. Kennedy, Jacob Pollock, David J. Clarke, Alan R. Brown, Dominic J. Campopiano
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 1, Pp 137-150 (2017)
Sphingolipids (SLs) are ubiquitous elements in eukaryotic membranes and are also found in some bacterial and viral species. As well as playing an integral structural role, SLs also act as potent signaling molecules involved in numerous cellular pathw
Externí odkaz:
https://doaj.org/article/b88abd542b6b4e52bfb50f3531326388
Publikováno v:
Applied Microbiology and Biotechnology
α-Dioxygenases (α-DOXs) are known as plant enzymes involved in the α-oxidation of fatty acids through which fatty aldehydes, with a high commercial value as flavor and fragrance compounds, are synthesized as products. Currently, little is known ab
Autor:
Keller Markus A., Watschinger Katrin, Golderer Georg, Werner-Felmayer Gabriele, Werner Ernst R.
Publikováno v:
Pteridines, Vol 24, Iss 1, Pp 105-109 (2013)
The tetrahydrobiopterin-dependent degradation of ether lipids by alkylglycerol monooxygenase (AGMO) produces fatty aldehydes, which are toxic to cells. Therefore, it is of great physiological importance that these harmful compounds are converted into
Externí odkaz:
https://doaj.org/article/ad14c89ecee74f02a71861ba701537f6
Autor:
Markus A. Keller, Katrin Watschinger, Karsten Lange, Georg Golderer, Gabriele Werner-Felmayer, Albin Hermetter, Ronald J.A. Wanders, Ernst R. Werner
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 7, Pp 1410-1416 (2012)
The lack of fatty aldehyde dehydrogenase function in Sjögren Larsson Syndrome (SLS) patient cells not only impairs the conversion of fatty aldehydes into their corresponding fatty acid but also has an effect on connected pathways. Alteration of the
Externí odkaz:
https://doaj.org/article/8fb5c905ce3a4469af76461f11f4d94d