Zobrazeno 1 - 10
of 132
pro vyhledávání: '"fatty acid oxidation, FAO"'
Autor:
Chaoying Qin, Shasha Gong, Ting Liang, Zhenbo Zhang, Jessie Thomas, Janice Deng, Yaguang Liu, Peiqing Hu, Bi Zhu, Shujie Song, Marisol Fernández Ortiz, Yuji Ikeno, Exing Wang, James Lechleiter, Susan T. Weintraub, Yidong Bai
Publikováno v:
Advanced Science, Vol 11, Iss 47, Pp n/a-n/a (2024)
Abstract Oxidative phosphorylation (OXPHOS) and fatty acid oxidation (FAO) are key bioenergetics pathways. The machineries for both processes are localized in mitochondria. Secondary OXPHOS defects have been documented in patients with primary FAO de
Externí odkaz:
https://doaj.org/article/4a65a6e132004df783d3baf65f858ef1
Autor:
Audrey Roy-Dorval, Rebecca C. Deagle, Frederik Roth, Mathilde Raybaud, Nailya Ismailova, Sai Sakktee Krisna, Damon G. K. Aboud, Camille Stegen, Julien Leconte, Gabriel Berberi, Ademola Esomojumi, Jörg H. Fritz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Group 2 Innate Lymphoid Cells (ILC2) are critical drivers of both innate and adaptive type 2 immune responses, known to orchestrate processes involved in tissue restoration and wound healing. In addition, ILC2 have been implicated in chronic inflamma
Externí odkaz:
https://doaj.org/article/232266beb9b34ddfbdbe29abd27fee3f
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cellular metabolism is a crucial determinant of immune cell fate and function. Extensive studies have demonstrated that metabolic decisions influence immune cell activation, differentiation, and cellular capacity, in the process impacting an organism
Externí odkaz:
https://doaj.org/article/ee5e45828f4d4c0faa1f2607c2d21c87
Autor:
Christopher D. Radka, Matthew W. Frank, Tyler S. Simmons, Cydney N. Johnson, Jason W. Rosch, Charles O. Rock
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Commensal gut bacteria use oleate hydratase to release a spectrum of hydroxylated fatty acids using host-derived unsaturated fatty acids. These compounds are thought to attenuate the immune response, but the underlying signaling mechanism(s) remain t
Externí odkaz:
https://doaj.org/article/70f3502acdec48fe9505c1796b4179e0
Autor:
Renan Muniz-Santos, Giovanna Lucieri-Costa, Matheus Augusto P. de Almeida, Isabelle Moraes-de-Souza, Maria Alice Dos Santos Mascarenhas Brito, Adriana Ribeiro Silva, Cassiano Felippe Gonçalves-de-Albuquerque
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Sepsis is a life-threatening organ dysfunction caused by abnormal host response to infection. Millions of people are affected annually worldwide. Derangement of the inflammatory response is crucial in sepsis pathogenesis. However, metabolic, coagulat
Externí odkaz:
https://doaj.org/article/5d5b8118273d4abc87cabf530a9a3e0a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Heart failure (HF) remains a disease with immense global health burden. During the development of HF, the myocardium and therefore cardiac metabolism undergoes specific changes, with decreased long-chain fatty acid oxidation and increased anaerobic g
Externí odkaz:
https://doaj.org/article/e84cf2a2c8e341e28f92f3095870f1fe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Over the last decades, the frequency of allergic disorders has steadily increased. Immunologically, allergies are caused by abnormal immune responses directed against otherwise harmless antigens derived from our environment. Two of the main cell type
Externí odkaz:
https://doaj.org/article/ccd533471bb74622b3e2faf057f5a9e0
Autor:
Joséphine Gander, Justin Carrard, Hector Gallart-Ayala, Rébecca Borreggine, Tony Teav, Denis Infanger, Flora Colledge, Lukas Streese, Jonathan Wagner, Christopher Klenk, Gilles Nève, Raphael Knaier, Henner Hanssen, Arno Schmidt-Trucksäss, Julijana Ivanisevic
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Coronary artery disease (CAD) remains the leading cause of death worldwide. Expanding patients' metabolic phenotyping beyond clinical chemistry investigations could lead to earlier recognition of disease onset and better prevention strategies. Additi
Externí odkaz:
https://doaj.org/article/c76fbd9560b04fb3b8c2021aaf095933
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Lipid metabolism involves multiple biological processes. As one of the most important lipid metabolic pathways, fatty acid oxidation (FAO) and its key rate-limiting enzyme, the carnitine palmitoyltransferase (CPT) system, regulate host immune respons
Externí odkaz:
https://doaj.org/article/892af5351f5941f185005cf932d3a128
Autor:
Priya Khurana, Chakkapong Burudpakdee, Stephan A. Grupp, Ulf H. Beier, David M. Barrett, Hamid Bassiri
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Invariant natural killer T (iNKT) cells comprise a unique subset of lymphocytes that are primed for activation and possess innate NK-like functional features. Currently, iNKT cell-based immunotherapies remain in early clinical stages, and little is k
Externí odkaz:
https://doaj.org/article/cba694a0cd1e44b5a960cff9055f4538