Zobrazeno 1 - 10
of 51
pro vyhledávání: '"farnesiferol c"'
Publikováno v:
Dermatologica Sinica, Vol 41, Iss 1, Pp 8-17 (2023)
Background: Hyperpigmentation occurs when excess melanin accumulates in the skin and causes the skin to become darker in color. Pursuing attractive appearance and colorism have promoted the development of the skin whitening market globally. The prote
Externí odkaz:
https://doaj.org/article/96970389c50141a2852f4eff6b80ab35
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1070 (2022)
Farnesiferol C (Far-C) is a coumarin commonly extracted from Ferula asafetida and is popularly used as a traditional source of natural remedy. Liver cancer or hepatocellular carcinoma (HCC) has emerged as a major cause behind cancer burden, and limit
Externí odkaz:
https://doaj.org/article/57299215e6cf443c9a877f2def5a57d6
Publikováno v:
Avicenna Journal of Phytomedicine, Vol 8, Iss 4, Pp 296-312 (2018)
Objective: The genus Ferula L. includes perennial flowering plants belonging to the Apiaceae family. This genus is a rich source of biologically active phytochemicals such as sulfur-containing derivatives, coumarins, sesquiterpenes, sesquiterpene lac
Externí odkaz:
https://doaj.org/article/e858aa442ad4471ba54767df9ba78e70
Akademický článek
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Akademický článek
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Autor:
Pouria Samadi, Massoud Saidijam, Hamid Tanzadehpanah, Dara Dastan, Neda Hosseinpour Moghadam, Hanie Mahaki, Jamshid Karimi, Sadegh Salehzadeh
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 37:2789-2800
In this study, Farnesiferol C was introduced as an anti-colon cancer agent. Its cytotoxicity was investigated on two cancer cell lines, HCT116 and CT26, and mesenchymal stem cells (MSCs) as normal ...
Autor:
Ameneh Mohammadi, Jamal Kasaian
Publikováno v:
Journal of Asian Natural Products Research. 20:27-35
Farnesiferol C (FC) is a sesquiterpene coumarin, with a unique chemical structure, isolated from Ferula (Apiaceae) species including Ferula assa-foetida and Ferula szowitsiana. The compound is an important natural product with different biological ac
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 4, Iss, Pp 420-426 (2017)
Toxicology Reports, Vol 4, Iss, Pp 420-426 (2017)
Graphical abstract
Highlights • Farnesiferol C (FC) reduced viability in MCF-7 cells. • This compound causes G0/G1 cell cycle arrest in the cells. • The FC leads to cellular oxidative stress and induction of apoptosis in MCF-7 cells.
Highlights • Farnesiferol C (FC) reduced viability in MCF-7 cells. • This compound causes G0/G1 cell cycle arrest in the cells. • The FC leads to cellular oxidative stress and induction of apoptosis in MCF-7 cells.
Autor:
Ji Eon Park, Ji Hoon Jung, Deok Yong Sim, Duckgue Lee, Woon Yi Park, Sung-Hoon Kim, Eunji Im, Bumsang Shim
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 22
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5535 (2019)
Volume 20
Issue 22
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5535 (2019)
Herein the underlying apoptotic mechanism of Farnesiferol C (FC) derived from Ferula assafoetida was elucidated in chronic myelogenous leukemia (CML) K562 and KBM5 cells. FC showed significant cytotoxicity in K562 and KBM5 cells, more so than in U937