Výsledky vyhledávání - "facteur de croissance igf 1"

The Insulin-like Growth Factor-1 Binding Protein Acid-labile Subunit Alters Mesenchymal Stromal Cell Fate

Autor: Sebastien Elis, Clifford J. Rosen, Hui Sun, Shoshana Yakar, Yuki Kawashima, Yinjgie Wu, Hayden Williams Courtland, David R. Clemmons, J. Christopher Fritton, Wilson Mejia

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (7), pp.4709-4714. ⟨10.1074/jbc.M109.041913⟩
Journal of Biological Chemistry 7 (285), 4709-4714. (2010)

Article en "Free Access"; International audience; Age-related osteoporosis is accompanied by an increase in marrow adiposity and a reduction in serum insulin-like growth factor-1 (IGF-1) and the binding proteins that stabilize IGF-1. To determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0d589538eee76ed542213b71953825
https://doi.org/10.1074/jbc.m109.041913

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Unbound (bioavailable) IGF1 enhances somatic growth

Autor: Luis Cardoso, Hui Sun, Jan Frystyk, Hayden William Courtland, Liliana Karabatas, Chengyu Liu, Sebastien Elis, Jelena Basta-Pljakic, Shoshana Yakar, Mordechay Beth-On, Hector Jasper, Yingjie Wu, Clifford J. Rosen, Horacio Domene, Dara Cannata, Clara Guida

Publikováno v: Elis, S, Wu, Y, Courtland, H-W, Cannata, D, Sun, H, Beth-On, M, Liu, C, Jasper, H, Domené, H, Karabatas, L, Guida, C, Basta-Pljakic, J, Cardoso, L, Rosen, C J, Frystyk, J & Yakar, S 2011, ' Unbound (bioavailable) IGF1 enhances somatic growth ', Disease Models and Mechanisms, vol. 4, no. 5, pp. 649-58 . https://doi.org/10.1242/dmm.006775
Disease Models & Mechanisms
Disease Models & Mechanisms, Cambridge Company of Biologists, 2011, 4 (5), pp.649-658. ⟨10.1242/dmm.006775⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
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Disease Models and Mechanisms 5 (4), 649-658. (2011)
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 649-658 (2011)

Understanding insulin-like growth factor-1 (IGF1) biology is of particular importance because, apart from its role in mediating growth, it plays key roles in cellular transformation, organ regeneration, immune function, development of the musculoskel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a330c66aae55d6f63bb78ba11cd6836
https://pure.au.dk/portal/da/publications/unbound-bioavailable-igf1-enhances-somatic-growth(3ce07b3a-f2cf-4047-b28f-c726071bc520).html

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Increased serum IGF-1 levels protect the musculoskeletal system but are associated with elevated oxidative stress markers and increased mortality independent of tissue igf1 gene expression

Autor: Sebastien, Elis, YingJie, Wu, Hayden-William, Courtland, Hui, Sun, Clifford J, Rosen, Martin L, Adamo, Shoshana, Yakar

Publikováno v: Aging Cell 3 (10), 547-550. (2011)
Aging Cell
Aging Cell, Wiley Open Access, 2011, 10 (3), pp.547-550. ⟨10.1111/j.1474-9726.2011.00683.x⟩

Although the literature suggests a protective (anabolic) effect of insulin-like growth factor-1 (IGF-1) on the musculoskeletal system during growth and aging, there is evidence that reductions in IGF-1 signaling are advantageous for promoting an incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e67bfd7dab1fbddd6d7820359c53c0dd
http://prodinra.inra.fr/record/281367

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Insulin-like Growth Factor-1 binding proteins alter osteoclastogenesis

Autor: Fritton, J. Christopher, Kawashima, Y., Courtland, H.W., Elis, Sébastien, Yakar, S.

Publikováno v: 56. Annual Meeting of the Orthopaedic Research Society
56. Annual Meeting of the Orthopaedic Research Society, Orthopaedic Research Society. USA., Mar 2010, New Orleans, United States. 1 p
56. Annual Meeting of the Orthopaedic Research Society, New Orleans, USA, 2010-03-06-2010-03-09

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::85e11b01fd4c06a5cd957dbb262e96f4
https://hal.inrae.fr/hal-02816280/file/2010_Fritton_OrthopaedicResSoc_1.pdf

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Increased levels of serum IGF-1 can rescue the skeletal impairment of female IGF-1 null mice but are insufficient for the rescue of the male skeleton

Autor: Elis, Sébastien, Courtland, Hayden-William, Wu, Vingjie, Sun, Hui, Williams, Valerie, Jepsen, Karl, Yakar, Shoshana

Publikováno v: 31. Annual Meeting of the American Society for Bone and Mineral Research
31. Annual Meeting of the American Society for Bone and Mineral Research, Sep 2009, Denver, United States. Journal of Bone and Mineral Research, 24 (Supplement 1), 2009, Thirty-first Annual Meeting of the American Society for Bone and Mineral Research
Thirty-first Annual Meeting of the American Society for Bone and Mineral Research . (24 (Supplement 1))2009; 31. Annual Meeting of the American Society for Bone and Mineral Research, Denver, USA, 2009-09-11-2009-09-15, S420

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ed0b5f47a6753eb70905f439298c90d4
https://hal.inrae.fr/hal-02755337/document

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Elevated levels of serum IGF-1 restore peak bone properties in the absence of tissue IGF-1 and enhance bone properties in its presence

Autor: Elis, Sébastien, Courtland, Hayden-William, Wu, Yingjie, Sun, Hui, Williams, Valerie, Jepsen, Karl, Yakar, Shoshana

Publikováno v: Gordon Research Conference
Gordon Research Conference, Mar 2009, Ventura, United States. 1 p., 2009
Gordon Research Conference, Ventura, USA, 2009-03-22-2009-03-27

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fd16c73d2642f6af79092e6d82f3238f
https://hal.inrae.fr/hal-02816106

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Free IGF-1 can increase body size and bone length in face of significant reductions in serum IGF-1

Autor: Elis, Sébastien, Wu, Yingjie, Courtland, Hayden-William, Sun, Hui, Williams, Valerie, Jepsen, Karl, Yakar, Shoshana

Publikováno v: Thirty-first Annual Meeting of the American Society for Bone and Mineral Research. (24 (Supplement 1))2009; 31. Annual Meeting of the American Society for Bone and Mineral Research, Denver, USA, 2009-09-11-2009-09-15, S181

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1582::a0babef819212430b6908af198e70104
http://prodinra.inra.fr/record/281379

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Insulin-like growth factor-I and -II binding and action on DNA synthesis in rainbow trout spermatogonia and spermatocytes

Autor: Loir, Maurice, Le Gac, Florence

Publikováno v: Biology of Reproduction (51), 1154-1163. (1994)
Biology of Reproduction
Biology of Reproduction, Society for the Study of Reproduction, 1994, 51, pp.1154-1163. ⟨10.1095/biolreprod51.6.1154⟩

International audience; Radio-labeled recombinant human insulin-like growth factor (I-125-rhIGF-I) bound specifically to total testicular cells and to spermatogonia plus primary spermatocytes (Go+Cl) that had been prepared from trout testes at variou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a91f66f6ba95ac291b47116d162c9cf4
https://pubmed.ncbi.nlm.nih.gov/7534123

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Facteurs de croissance de type insulinique et regulation gonadique chez les poissons

Autor: Fostier, Alexis, Le Gac, Florence, Loir, M.

Publikováno v: Contraception Fertilité Sexualité (22), 548-550. (1994)

Recent data showing the occurrence of IGF in fish, mainly teleostean fish, and their biological activity in gonads are reviewed. IGF-I does occur in all vertebrates and first evidence of IGF-II occurrence in fish has been reported. IGF-I is expressed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1582::3bb7887eece54c570fd328106a434b1b
http://prodinra.inra.fr/record/119425

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