Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide–gated and ryanodine 2 channels

Autor: Saeed, Yawer, Temple, Ian, Borbas, Zoltan, Atkinson, Andrew, Yanni Gerges, Joseph, Maczewski, Michał, Mackiewicz, U., Aly, M, Logantha, Sunil, Garratt, Clifford, Dobrzynski, Halina

Publikováno v: Heart Rhythm
Saeed, Y, Temple, I P, Borbas, Z, Atkinson, A, Yanni Gerges, J, Maczewski, M, Mackiewicz, U, Aly, M, Logantha, S, Garratt, C & Dobrzynski, H 2018, ' Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels ', Heart Rhythm . https://doi.org/10.1016/j.hrthm.2017.12.027
Saeed, Y, Temple, I, Borbas, Z, Atkinson, A, Yanni Gerges, J, Maczewski, M, Mackiewicz, U, Aly, M, Logantha, S, Garratt, C & Dobrzynski, H 2017, ' Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels ' Heart Rhythm . DOI: 10.1016/j.hrthm.2017.12.027

Background Aging is associated with an increased incidence of atrioventricular nodal (AVN) dysfunction. Objective The aim of this study was to investigate the structural and functional remodeling in the atrioventricular junction (AVJ) with aging. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::75488a094cbc5a06658bd10c2a064bd3
http://europepmc.org/articles/PMC5934612

Ivabradine: Evidence and current role in cardiovascular diseases and other emerging indications

Autor: Immaneni Sathyamurthy, Sanket Newale

Publikováno v: Indian Heart Journal, Vol 70, Iss, Pp S435-S441 (2018)
Indian Heart Journal

Increased heart rate (HR) is associated with deleterious effects on several disease conditions. Chronic heart failure (CHF) is one of the cardiovascular diseases with recurrent hospitalization burden and an ongoing drain on health-care expenditure. D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03f1b5c83c67173e09f575aa9bc1b4d
http://www.sciencedirect.com/science/article/pii/S0019483218301652

Expert consensus document: A 'diamond' approach to personalized treatment of angina

Autor: Ferrari, R, Camici, PG, Crea, F, Danchin, N, Fox, K, Maggioni, AP, Manolis, AJ, Marzilli, M, Rosano, GMC, Lopez-Sendon, JL

Publikováno v: Nature reviews. Cardiology. 15(2)

In clinical guidelines, drugs for symptomatic angina are classified as being first choice (β-blockers, calcium-channel blockers, short-acting nitrates) or second choice (ivabradine, nicorandil, ranolazine, trimetazidine), with the recommendation to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::77d953e2b0a1a8a6ca12ec1923d7f590
https://pubmed.ncbi.nlm.nih.gov/28880025

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