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pro vyhledávání: '"eye/retina"'
Akademický článek
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Autor:
Alexandra Bernardo-Colón, Lijin Dong, Mones Abu-Asab, Richard S. Brush, Martin-Paul Agbaga, S. Patricia Becerra
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 5, Pp 100358- (2023)
Photoreceptor cells express the patatin-like phospholipase domain-containing 2 (PNPLA2) gene that codes for pigment epithelium-derived factor receptor (PEDF-R) (also known as ATGL). PEDF-R exhibits phospholipase activity that mediates the neurotrophi
Externí odkaz:
https://doaj.org/article/e6edfbfcaeb9463cb8396dbeb2decb19
Autor:
Glenda Vasku, Caroline Peltier, Zhiguo He, Gilles Thuret, Philippe Gain, Pierre-Henry Gabrielle, Niyazi Acar, Olivier Berdeaux
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 3, Pp 100343- (2023)
Evaluating lipid profiles in human tissues and biofluids is critical in identifying lipid metabolites in dysregulated metabolic pathways. Due to various chemical characteristics, single-run lipid analysis has not yet been documented. Such approach is
Externí odkaz:
https://doaj.org/article/160fd3ecb871407cb60348ed9cdfce5a
Autor:
Yeboah Kofi Gyening, Neeraj Kumar Chauhan, Madison Tytanic, Vicki Ea, Richard S. Brush, Martin-Paul Agbaga
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 1, Pp 100317- (2023)
The FA Elongase-4 (ELOVL4) enzyme mediates biosynthesis of both very long chain (VLC)-PUFAs and VLC-saturated FA (VLC-SFAs). VLC-PUFAs play critical roles in retina and sperm function, whereas VLC-SFAs are predominantly associated with brain function
Externí odkaz:
https://doaj.org/article/837b278313024f33a618f388b91f0798
Publikováno v:
Measurement: Sensors, Vol 24, Iss , Pp 100511- (2022)
Recently, cloud computing (CC) received significant interest among organizations and individuals. Despite the significant benefits of CC, security and privacy are considered as the major issue. Biometric authentication is commonly employed for authen
Externí odkaz:
https://doaj.org/article/e979949c9d7146daba39d8af9742eff6
Autor:
Casey N. Barber, Hana L. Goldschmidt, Brendan Lilley, Alexei M. Bygrave, Richard C. Johnson, Richard L. Huganir, Donald J. Zack, Daniel M. Raben
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 8, Pp 100247- (2022)
Phosphatidic acid is a key signaling molecule heavily implicated in exocytosis due to its protein-binding partners and propensity to induce negative membrane curvature. One phosphatidic acid-producing enzyme, phospholipase D (PLD), has also been impl
Externí odkaz:
https://doaj.org/article/ff4db0915c4049ca95f94efafaacc188
Publikováno v:
Атеросклероз, Vol 16, Iss 2, Pp 49-62 (2020)
Objective. In this work we analyzed the current literature data about the retinal damage in cardiovascular diseases and diabetes mellitus (published from 2005 to 2020). The damage of retinal vascular bed and optic nerve represents a relevant problem
Externí odkaz:
https://doaj.org/article/fc112136d3c04eb2b3c0bf929bb1f5d1
Autor:
Monika Lakk, Grace F. Hoffmann, Aruna Gorusupudi, Eric Enyong, Amy Lin, Paul S. Bernstein, Trine Toft-Bertelsen, Nanna MacAulay, Michael H. Elliott, David Križaj
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100145- (2021)
Despite the association of cholesterol with debilitating pressure-related diseases such as glaucoma, heart disease, and diabetes, its role in mechanotransduction is not well understood. We investigated the relationship between mechanical strain, free
Externí odkaz:
https://doaj.org/article/ddf84964e0c34f4f9e32ca66ec7cc420
Autor:
Hye Jin Kim, Janet R. Sparrow
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1620-1629 (2018)
Bisretinoids are a family of fluorophores that form in photoreceptor cells' outer segments by nonenzymatic reaction of two vitamin A aldehydes (A2) with phosphatidylethanolamine (PE). Bisretinoid fluorophores are the major constituents of the lipofus
Externí odkaz:
https://doaj.org/article/f1d59b0afc764d72b053789598d650c1
Autor:
Norimitsu Ban, Tae Jun Lee, Abdoulaye Sene, Zhenyu Dong, Andrea Santeford, Jonathan B. Lin, Daniel S. Ory, Rajendra S. Apte
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1414-1423 (2018)
Photoreceptors have high intrinsic metabolic demand and are exquisitely sensitive to metabolic perturbation. In addition, they shed a large portion of their outer segment lipid membranes in a circadian manner, increasing the metabolic burden on the o
Externí odkaz:
https://doaj.org/article/f37d5b70129147069a9c4ae9a8dbc85e