Zobrazeno 1 - 10
of 604
pro vyhledávání: '"exposure-response relationship"'
Autor:
Wen Li, Jia Wang, Wenzhong Huang, Yu Yan, Yanming Liu, Qi Zhao, Mingting Chen, Liping Yang, Yuming Guo, Wei Ma
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Under a changing climate, the joint effects of temperature and relative humidity on tuberculosis (TB) are poorly understood. To address this research gap, we conducted a time-series study to explore the joint effects of temperatur
Externí odkaz:
https://doaj.org/article/98c99f4ac6e94149a992b76403286f1c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Toxic metals are vital risk factors affecting serum ion balance; however, the effect of their co-exposure on serum ions and the underlying mechanism remain unclear. We assessed the correlations of single metal and mixed metals with serum ion
Externí odkaz:
https://doaj.org/article/f886567630c74f848edb5b88794aa79c
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveSAF-189s is a potent ALK/ROS1 inhibitor that is currently in clinical development for treating advanced ALK+/ROS1+ non-small cell lung cancer (NSCLC). Comprehensive population pharmacokinetics (PopPK) and exposure–response models were deve
Externí odkaz:
https://doaj.org/article/781117d2f18b49b1ad708847a0666c61
Autor:
Lina Xiao, Qiling Wang, Haobo Ni, Ting Xu, Xiaoyan Cai, Tingting Dai, Lingxi Wang, Chunying Song, Yushan Li, Fuping Li, Tianqing Meng, Huiqiang Sheng, Xiaolin Yu, Qinghui Zeng, Pi Guo, Xinzong Zhang
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26765- (2024)
Backgrounds: Global fertility rates continue to decline and sperm quality is a prime factor affecting male fertility. Both extreme cold and heat have been demonstrated to be associated with decreased sperm quality, but no epidemiological studies have
Externí odkaz:
https://doaj.org/article/a2ee1fd471974a12b4b402319a35568d
Publikováno v:
Shanghai yufang yixue, Vol 35, Iss 10, Pp 970-975 (2023)
ObjectiveTo explore the association between air pollutants and hospital outpatient visits in a district of Shanghai.MethodsDaily meteorological data， environmental data， data of outpatient visits to two secondary hospitals and two tertiary hospit
Externí odkaz:
https://doaj.org/article/62ae6b8f40c2402fa66b374c23801e43
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 270, Iss , Pp 115829- (2024)
Impact of air pollution on incident chronic kidney disease (CKD) in diabetic patients is insufficiently studied. We aimed to examine exposure-response associations of PM2.5, PM10, PM2.5–10, NO2, and NOX with incident CKD in diabetic patients in the
Externí odkaz:
https://doaj.org/article/d696704312f942c49217ace1861e2449
Autor:
Yi Xiang, Hao Xu, Hongxiang Chen, Dan Tang, Zitong Huang, Yuan Zhang, Zhenghong Wang, Ziyun Wang, Yangla, Mingming Han, Jianzhong Yin, Xiong Xiao, Xing Zhao
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 42, Iss , Pp 100955- (2024)
Summary: Background: The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the biolog
Externí odkaz:
https://doaj.org/article/54e9d5d99e2d4bc9a80aa4c4e5f19094
Autor:
Gennyne Walker, Ryan Adams, Lauren Guy, Abhijeeth Chandrasekaran, Nelson Kinnersley, Pavithra Ramesh, Lu Zhang, Fran Brown, Vis Niranjan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Preliminary evidence for efficacy in pulmonary sarcoidosis has been shown for efzofitimod. Here we present supportive evidence of efficacy based on an exposure-response analysis.Methods: Data from two studies (Phase 1, N = 24, single dose
Externí odkaz:
https://doaj.org/article/3f7393ecf74b4edbbe2b6fa84a82a5d3
Autor:
Calvin Jephcote, Sierra N. Clark, Anna L. Hansell, Nigel Jones, Yingxin Chen, Claire Blackmore, Katie Eminson, Megan Evans, Xiangpu Gong, Kathryn Adams, Georgia Rodgers, Benjamin Fenech, John Gulliver
Publikováno v:
Environment International, Vol 178, Iss , Pp 107966- (2023)
Background: Noise pollution from transportation is one of the leading contributors to the environmental disease burden in Europe. We provide a novel assessment of spatial variations of these health impacts within a country, using England as an exampl
Externí odkaz:
https://doaj.org/article/4b410feca1e14cd893aa7af43b8ebe6d
Publikováno v:
Environmental Research Letters, Vol 19, Iss 7, p 074049 (2024)
Non-optimal temperatures significantly influence public health. However, the role of socio-economic factors in modulating health risks associated with non-optimal temperatures varies geographically and among different populations. Thus, the meteorolo
Externí odkaz:
https://doaj.org/article/42966189631140a2a10faad7e311b8a4