Zobrazeno 1 - 10
of 533
pro vyhledávání: '"experimental cerebral malaria"'
Autor:
Yi Wang, Yan Shen, Jiao Liang, Shubiao Wang, Yuxiao Huang, Qinghao Zhu, Xizhi Zhang, Kangjie Yu, Guodong Tong, Chao Yang, Yinghui Li, Jun Wang, Ya Zhao
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Cerebral malaria (CM) is the most lethal complication of malaria, and survivors usually endure neurological sequelae. Notably, the cytotoxic effect of infiltrating Plasmodium-activated CD8+ T cells on cerebral microvasculature end
Externí odkaz:
https://doaj.org/article/0b75044acc5a4aed93c5ae203466a374
Autor:
Zhuoru Jin, Wei Pang, Yan Zhao, Hui Min, Shijie Yao, Zhifang Bian, Yixin Wen, Chuanyang Peng, Yaming Cao, Li Zheng
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 25, Iss , Pp 100539- (2024)
Infection with Plasmodium falciparum is often deadly when it results in cerebral malaria, which is associated with neuropathology described as an overwhelming inflammatory response and mechanical obstruction of cerebral microvascular. PI3Kγ is a cri
Externí odkaz:
https://doaj.org/article/0f7ec9bd8b7949fa84774949969d4223
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Plasmodium berghei has been used as a preferred model for studying human malaria, but only a limited number of disease-associated genes of P. berghei have been reported to date. Identification of new disease-related genes as many
Externí odkaz:
https://doaj.org/article/fdeeb250f586446caddcf4a4dbd8cdfb
Autor:
Walaiporn Plirat, Prapaporn Chaniad, Arisara Phuwajaroanpong, Atthaphon Konyanee, Parnpen Viriyavejakul, Abdi Wira Septama, Chuchard Punsawad
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Cerebral malaria is one of the most serious complications of Plasmodium infection and causes behavioral changes. However, current antimalarial drugs have shown poor outcomes. Therefore, new antimalarials with neuroprotective effec
Externí odkaz:
https://doaj.org/article/868f176a6f774a93b74129457e362d1e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Matthias H. Enders, Ganchimeg Bayarsaikhan, Sonia Ghilas, Yu Cheng Chua, Rose May, Maria N. de Menezes, Zhengyu Ge, Peck Szee Tan, Anton Cozijnsen, Vanessa Mollard, Katsuyuki Yui, Geoffrey I. McFadden, Mireille H. Lahoud, Irina Caminschi, Anthony W. Purcell, Ralf B. Schittenhelm, Lynette Beattie, William R. Heath, Daniel Fernandez-Ruiz
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 79-92 (2021)
Thorough understanding of the role of CD4 T cells in immunity can be greatly assisted by the study of responses to defined specificities. This requires knowledge of Plasmodium-derived immunogenic epitopes, of which only a few have been identified, es
Externí odkaz:
https://doaj.org/article/ae70f072848a4eb3bfa16dbb9ca365ca
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
In malaria, anti-parasite immune response of the host may lead to dysregulated inflammation causing severe neuropathology arising from extensive damage to the Blood Brain Barrier (BBB). Use of anti-malarial drugs alone can control parasitemia and red
Externí odkaz:
https://doaj.org/article/c644da990fe04678b9c7ba1e7bcac8f4
Autor:
Fernanda de Moura Alves, Jessica Correa Bezerra Bellei, Camila de Souza Barbosa, Caíque Lopes Duarte, Amanda Luisa da Fonseca, Ana Claudia de Souza Pinto, Felipe Oliveira Raimundo, Bárbara Albuquerque Carpinter, Ari Sérgio de Oliveira Lemos, Elaine Soares Coimbra, Alex Gutterres Taranto, Vinícius Novaes Rocha, Fernando de Pilla Varotti, Gustavo Henrique Ribeiro Viana, Kézia K. G. Scopel
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1529 (2022)
Malaria is an infectious disease widespread in underdeveloped tropical regions. The most severe form of infection is caused by Plasmodium falciparum, which can lead to development of cerebral malaria (CM) and is responsible for deaths and significant
Externí odkaz:
https://doaj.org/article/d1a5836d18ba416a8d881bce8fde5ae7
Autor:
Johanna F. Scheunemann, Julia J. Reichwald, Patricia Jebett Korir, Janina M. Kuehlwein, Lea-Marie Jenster, Christiane Hammerschmidt-Kamper, Matthew D. Lewis, Katrin Klocke, Max Borsche, Kim E. Schwendt, Camille Soun, Stephanie Thiebes, Andreas Limmer, Daniel R. Engel, Ann-Kristin Mueller, Achim Hoerauf, Marc P. Hübner, Beatrix Schumak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cerebral malaria is a potentially lethal disease, which is caused by excessive inflammatory responses to Plasmodium parasites. Here we use a newly developed transgenic Plasmodium berghei ANKA (PbAAma1OVA) parasite that can be used to study parasite-s
Externí odkaz:
https://doaj.org/article/d731aa41bf42464ead8cc7486303f906