Zobrazeno 1 - 10
of 276
pro vyhledávání: '"experimental autoimmune encephalitis"'
Autor:
Amin Daei Sorkhabi, Erfan Komijani, Aila Sarkesh, Pedram Ghaderi Shadbad, Ali Aghebati-Maleki, Leili Aghebati-Maleki
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Beyond the encouraging results and broad clinical applicability of immune checkpoint (ICP) inhibitors in cancer therapy, ICP-based immunotherapies in the context of autoimmune disease, particularly multiple sclerosis (MS), have garnered cons
Externí odkaz:
https://doaj.org/article/8e2c4e3669b74e2fa5ec3e3532d28af7
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD24 is a GPI anchored cell surface glycoprotein whose function as a co-stimulatory molecule has been implicated. However, the function of CD24 on antigen presenting cells during T cell responses is not well understood. Here we show that in the CD24-
Externí odkaz:
https://doaj.org/article/5889a65d58f74f74ac5a4564204942f4
Autor:
Sinduya Krishnarajah, Burkhard Becher
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The invasion of immune cells into the central nervous system (CNS) is a hallmark of the process we call neuroinflammation. Diseases such as encephalitides or multiple sclerosis (MS) are characterised by the dramatic influx of T lymphocytes and monocy
Externí odkaz:
https://doaj.org/article/56cb0447cfc044919fd1cbb2fe017cfa
Akademický článek
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Autor:
David W. Scott
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chimeric antigen receptor (CAR) transduced T cells have significantly improved cancer immunotherapy. Similarly, engineering regulatory T cells (Treg) with specific receptors to endow specificity and increase efficacy of Tregs holds great promise for
Externí odkaz:
https://doaj.org/article/b677ad709cac478085b57e61625ab7e9
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 14, Iss , Pp 100262- (2021)
Multiple Sclerosis (MS) is an immune-mediated disease that results in major locomotor deficits. However, recent studies have revealed that fatigue, slow processing speed, and memory impairment are the top variables impacting employment status for MS
Externí odkaz:
https://doaj.org/article/0e95130cd28b484fa7a4d1687ade6b43
Autor:
Cristian R. Falcón, Nicolás Fernández Hurst, Ana Laura Vivinetto, Pablo Héctor Horacio López, Adolfo Zurita, Gerardo Gatti, Laura Cervi, Clara G. Monferran, German A. Roth
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Currently there is increasing attention on the modulatory effects of benzodiazepines on the immune system. Here, we evaluate how Diazepam (DZ) affects both innate and adaptive immunity. We observed that treatment with DZ and Lipopolysaccharide (LPS)
Externí odkaz:
https://doaj.org/article/2f4be6b14c0d477685f964e27722f578
Autor:
Barakat Alrashdi, Bassel Dawod, Andrea Schampel, Sabine Tacke, Stefanie Kuerten, Jean S. Marshall, Patrice D. Côté
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background In multiple sclerosis (MS) and in the experimental autoimmune encephalomyelitis (EAE) model of MS, the Nav1.6 voltage-gated sodium (Nav) channel isoform has been implicated as a primary contributor to axonal degeneration. Followin
Externí odkaz:
https://doaj.org/article/efe52f70917a403088eea9e0e338ee35
Autor:
Borros M. Arneth
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Introduction Multiple sclerosis (MS) is a chronic autoimmune disorder that affects the central nervous system and compromises the health and well-being of millions of people worldwide. B cells have been linked to MS and its progression. This
Externí odkaz:
https://doaj.org/article/bb33940a3b2b466fbca455061e41aac0
Autor:
Maryam S. Seyedsadr, Oliver Weinmann, Ana Amorim, Benjamin V. Ineichen, Matteo Egger, Javad Mirnajafi-Zadeh, Burkhard Becher, Mohammad Javan, Martin E. Schwab
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 189-201 (2019)
Multiple sclerosis is an inflammatory disease of the central nervous system (CNS) in which multiple sites of blood-brain barrier (BBB) disruption, focal inflammation, demyelination and tissue destruction are the hallmarks. Here we show that sphingosi
Externí odkaz:
https://doaj.org/article/5e4c82486955409889c724d5c9e6f988