Umbilical cord mesenchymal stromal cells transplantation delays the onset of hyperglycemia in the RIP-B7.1 mouse model of experimental autoimmune diabetes through multiple immunosuppressive and anti-inflammatory responses

Autor: C. C. Lachaud, N. Cobo-Vuilleumier, E. Fuente-Martin, I. Diaz, E. Andreu, G. M. Cahuana, J. R. Tejedo, A. Hmadcha, B. R. Gauthier, B. Soria

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Type 1 diabetes mellitus (T1DM) is an autoimmune disorder specifically targeting pancreatic islet beta cells. Despite many efforts focused on identifying new therapies able to counteract this autoimmune attack and/or stimulate beta cells regeneration

Externí odkaz: https://doaj.org/article/1b69132433894b40b436f57bc44081c3

Genetic differentiation of Poly I:C from B:9-23 peptide induced experimental autoimmune diabetes

Autor: Dongmei Miao, Hiroaki Moriyama, Edwin Liu, Evie Melanitou, Robert M. Taylor, Liping Yu, Devasenan Devendra, Akane Ide, Johanna Paronen, George S. Eisenbarth

Publikováno v: Journal of Autoimmunity
Journal of Autoimmunity, Elsevier, 2004, 22 (4), pp.307-313. ⟨10.1016/j.jaut.2004.01.006⟩
Journal of Autoimmunity, 2004, 22 (4), pp.307-313. ⟨10.1016/j.jaut.2004.01.006⟩

International audience; Type 1 diabetes is an immune-mediated disease, in which T cells of the adaptive immune system mediate beta cell destruction. Recently the innate immune system has been linked to etiopathogenesis of several autoimmune diseases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c12af64fc3fb06e3fecaeaafea05e5b
https://hal-pasteur.archives-ouvertes.fr/pasteur-01643774

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.