Zobrazeno 1 - 10
of 21
pro vyhledávání: '"exon replacement"'
Publikováno v:
Open Biology, Vol 11, Iss 1 (2021)
Precision genomic alterations largely rely on homology directed repair (HDR), but targeting without homology using the non-homologous end-joining (NHEJ) pathway has gained attention as a promising alternative. Previous studies demonstrated precise in
Externí odkaz:
https://doaj.org/article/b82c8fa0b53f4079b2dbf5b3b2dc2d5b
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 140-154 (2017)
Antiviral strategies targeting hijacked cellular processes are less easily evaded by the virus than viral targets. If selective for viral functions, they can have a high therapeutic index. We used RNA trans-splicing to deliver the herpes simplex viru
Externí odkaz:
https://doaj.org/article/59b2c961727f4e71b769d3e81773f282
Publikováno v:
Open Biology
Open Biology, Vol 11, Iss 1 (2021)
Open Biology, Vol 11, Iss 1 (2021)
Precision genomic alterations largely rely on Homology Directed Repair (HDR), but targeting without homology using the Non-Homologous End Joining (NHEJ) pathway has gained attention as a promising alternative. Previous studies demonstrated precise in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711b7ca1527b916772c8a8c70938cf98
http://edoc.mdc-berlin.de/19728/1/19728oa.pdf
http://edoc.mdc-berlin.de/19728/1/19728oa.pdf
Autor:
Guangrong Xie, Weizhen Yang, Jing Chen, Miaomiao Li, Nan Jiang, Baixue Zhao, Si Chen, Min Wang, Jianhua Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 5, p 764 (2016)
The activity of urate oxidase was lost during hominoid evolution, resulting in high susceptibility to hyperuricemia and gout in humans. In order to develop a more “human-like” uricase for therapeutic use, exon replacement/restoration and site-dir
Externí odkaz:
https://doaj.org/article/c3726606856a4989abb498a49ced891c
Autor:
Ingemarsdotter, Carin K., Poddar, Sushmita, Mercier, Sarah, Patzel, Volker, Lever, Andrew M.L.
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 140-154 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Antiviral strategies targeting hijacked cellular processes are less easily evaded by the virus than viral targets. If selective for viral functions, they can have a high therapeutic index. We used RNA trans-splicing to deliver the herpes simplex viru
Akademický článek
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Antiviral strategies targeting hijacked cellular processes are less easily evaded by the virus than viral targets. If selective for viral functions, they can have a high therapeutic index. We used RNA trans-splicing to deliver the herpes simplex viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8ae9e657a1424775292e5f2889e79f
https://www.repository.cam.ac.uk/handle/1810/264409
https://www.repository.cam.ac.uk/handle/1810/264409
Autor:
Weizhen Yang, Baixue Zhao, Jing Chen, Nan Jiang, Si Chen, Li Miaomiao, Jianhua Chen, Guangrong Xie, Min Wang
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 5; Pages: 764
International Journal of Molecular Sciences, Vol 17, Iss 5, p 764 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 5; Pages: 764
International Journal of Molecular Sciences, Vol 17, Iss 5, p 764 (2016)
The activity of urate oxidase was lost during hominoid evolution, resulting in high susceptibility to hyperuricemia and gout in humans. In order to develop a more “human-like” uricase for therapeutic use, exon replacement/restoration and site-dir
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
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