Zobrazeno 1 - 10
of 1 380
pro vyhledávání: '"excitatory synaptic transmission"'
Autor:
Yurong Wang, Hao Xu, Saiyong Chen, Junhao Chen, Qimeng Zheng, Yuanyuan Ma, Xinru Zhao, Ying Shi, Lei Xiao
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract The most pronounced neuropathological feature of Parkinson's disease (PD) is the loss of dopamine (DA) neurons in the substantia nigra compacta (SNc), which depletes striatal DA. Hypothalamic oxytocin is found to be reduced in PD patients an
Externí odkaz:
https://doaj.org/article/99792be5ee85449389ec54b3a7d6e028
Autor:
Ayako Kawaminami, Daisuke Yamada, Toshinori Yoshioka, Azumi Hatakeyama, Moeno Nishida, Keita Kajino, Tsuyoshi Saitoh, Hiroshi Nagase, Akiyoshi Saitoh
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 256-261 (2024)
Abstract Aim Excitatory projections from the prelimbic cortex (PL) to the basolateral nucleus of the amygdala (BLA) are implicated in the regulation of anxiety‐like behaviors, and we previously demonstrated that anxiolytic‐like effects of the sel
Externí odkaz:
https://doaj.org/article/b4c8e0fe11204d0f9b4c52cf4d1b04ad
Autor:
Yi Lu, Longyu Mu, Justin Elstrott, Chaoying Fu, Cailu Sun, Tonghui Su, Xiaofan Ma, Jia Yan, Hong Jiang, Jesse E. Hanson, Yang Geng, Yelin Chen
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105045- (2024)
Summary: Background: Schizophrenia, a debilitating psychiatric disorder, displays considerable interindividual variation in clinical presentations. The ongoing debate revolves around whether this heterogeneity signifies a continuum of severity linked
Externí odkaz:
https://doaj.org/article/cbaf650e8efe4b698fad41585b8367f6
Akademický článek
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Akademický článek
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Publikováno v:
Neurobiology of Stress, Vol 20, Iss , Pp 100473- (2022)
The hippocampus exerts inhibitory feedback on the release of glucocorticoids. Because the major hippocampal efferent projections are excitatory, it has been hypothesized that this inhibition is mediated by populations of inhibitory neurons in the hyp
Externí odkaz:
https://doaj.org/article/3f01e63f74e946719ebe639730f9efd3
Autor:
Min Yang, Peijia Lin, Wei Jing, Haokun Guo, Hongnian Chen, Yuanyuan Chen, Yi Guo, Yixue Gu, Miaoqing He, Junhong Wu, Xuejun Jiang, Zhen Zou, Xin Xu, Chengzhi Chen, Fei Xiao, Xuefeng Wang, Xin Tian
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Epilepsy is a common disease of the nervous system. Autophagy is a degradation process involved in epilepsy, and in turn, seizures can activate autophagy. Beclin1 plays a critical role in autophagy and participates in numerous physiological and patho
Externí odkaz:
https://doaj.org/article/8a5ba9fb67954c14a19edf19709da235
Autor:
Tetsuya Hori, Kohgaku Eguchi, Han-Ying Wang, Tomohiro Miyasaka, Laurent Guillaud, Zacharie Taoufiq, Satyajit Mahapatra, Hiroshi Yamada, Kohji Takei, Tomoyuki Takahashi
Publikováno v:
eLife, Vol 11 (2022)
Elevation of soluble wild-type (WT) tau occurs in synaptic compartments in Alzheimer’s disease. We addressed whether tau elevation affects synaptic transmission at the calyx of Held in slices from mice brainstem. Whole-cell loading of WT human tau
Externí odkaz:
https://doaj.org/article/303a293335904bf99cca8357b822bbd8
Autor:
Kohei Oyabu, Kotomi Takeda, Hiroyuki Kawano, Kaori Kubota, Takuya Watanabe, N. Charles Harata, Shutaro Katsurabayashi, Katsunori Iwasaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 2, Pp 76-82 (2020)
Astrocytes, comprising the primary glial-cell type, are involved in the formation and maturation of synapses, and thus contribute to sustainable synaptic transmission between neurons. Given that the animals in higher phylogenetic tree have brains wit
Externí odkaz:
https://doaj.org/article/12d62f8535f24f16bb3c4f678defc610