Zobrazeno 1 - 10
of 3 461
pro vyhledávání: '"ex-vivo expansion"'
Autor:
Radhika Tandon, Pranav Kumar Pandey, Tanveer Alam Khan, Amit Kumar Das, Mani Kalaivani, Misba Majood, Seema Kashyap, Seema Sen, Neiwete Lomi, Noopur Gupta, M. Vanathi, Sujata Mohanty
Publikováno v:
BMC Biotechnology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Bilateral ocular surface disease resulting from Stevens Johnson Syndrome (SJS) and chemical injuries are visually debilitating and difficult to treat. Ocular surface reconstruction by various means has been reported with variable
Externí odkaz:
https://doaj.org/article/1ea93121ddc04f579d5de3ba94676d0e
Autor:
Juanita Mellet, Candice L. Hendricks, Voula Stivaktas, Chrisna Durandt, Melvin A. Ambele, Michael S. Pepper
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Ex vivo haematopoietic stem/progenitor cell (HSPCs) expansion constitutes an important area of research, and has the potential to improve access to umbilical cord blood (UCB) as a source of stem cells for haematopoietic stem cell
Externí odkaz:
https://doaj.org/article/79229c6b5d14402b8a5116d7950c3316
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-4 (2024)
Abstract Hematopoietic stem cells (HSCs) have emerged as one of the most therapeutically significant adult stem cells, paving way for a range of novel curative regimens over decades. HSCs are transplanted, either directly or post restorative genetic
Externí odkaz:
https://doaj.org/article/aa65339518c1498cb6b8a9e555f08781
Autor:
Krasimira Aleksandrova, Jana Leise, Christoph Priesner, Murat Aktas, Michael Apel, Mario Assenmacher, Iris Bürger, Anne Richter, Pia Altefrohne, Christine Schubert, Astrid Holzinger, Markus Barden, Valerie Bezler, Michael von Bergwelt-Baildon, Peter Borchmann, Lilia Goudeva, Wolfgang Glienke, Lubomir Arseniev, Ruth Esser, Hinrich Abken, Ulrike Koehl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPoint-of-care (POC) manufacturing of chimeric antigen receptor (CAR) modified T cell has expanded rapidly over the last decade. In addition to the use of CD19 CAR T cells for hematological diseases, there is a growing interest in targetin
Externí odkaz:
https://doaj.org/article/f6589c518506495e91a9217ebb7da6b4
Autor:
André Branco, Janakiram Rayabaram, Cláudia C. Miranda, Ana Fernandes-Platzgummer, Tiago G. Fernandes, Suchitra Sajja, Cláudia L. da Silva, Mohan C. Vemuri
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
As caretakers of the hematopoietic system, hematopoietic stem cells assure a lifelong supply of differentiated populations that are responsible for critical bodily functions, including oxygen transport, immunological protection and coagulation. Due t
Externí odkaz:
https://doaj.org/article/8410714dd6fd4487b56ee05c8a3bbe25
Autor:
Katelyn R. Einloth, Scott Gayfield, Thomas McMaster, Alexander Didier, Lance Dworkin, Justin Fortune Creeden
Publikováno v:
BioImpacts, Vol 13, Iss 6, Pp 439-455 (2023)
Introduction: Immunotherapy has revolutionized how cancer is treated. Many of these immunotherapies rely on ex vivo expansion of immune cells, classically T cells. Still, several immunological obstacles remain, including tumor impermeability by immun
Externí odkaz:
https://doaj.org/article/108cbecef2d7450cb6830151afab2483
Publikováno v:
eLife, Vol 12 (2024)
The scarcity of hematopoietic stem cells (HSCs) restricts their use in both clinical settings and experimental research. Here, we examined a recently developed method for expanding rigorously purified murine HSCs ex vivo. After 3 weeks of culture, on
Externí odkaz:
https://doaj.org/article/3905155e244846d08981cb4fe022f738
Autor:
Kassandra J. Baron, Hēth R. Turnquist
Publikováno v:
Organogenesis, Vol 19, Iss 1 (2023)
ABSTRACTBased on successes in preclinical animal transplant models, adoptive cell therapy (ACT) with regulatory T cells (Tregs) is a promising modality to induce allograft tolerance or reduce the use of immunosuppressive drugs to prevent rejection. E
Externí odkaz:
https://doaj.org/article/89c8e652515c45e7bca87b5ca3b59f0d
Publikováno v:
Онкогематология, Vol 0, Iss 3, Pp 69-76 (2022)
Now mesenchymal stem cells (MSC) are more widely applied in different areas of medicine. However, despite requirement for considerable quantities of human MSC for clinical practice, there is restricted information concerning culture conditions optimi
Externí odkaz:
https://doaj.org/article/28ef7af22d0142259f0c0206524014aa
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