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MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype

Autor: Elsa Kress, Mathias Heikenwalder, Gerard Lina, David Bauché, Saskia Lippens, Claire Macari, Marie-Cécile Michallet, Mathias Chamaillard, Sophia Djebali, Emilie Plantamura, Lyvia Moudombi, Jacqueline Marvel, Christophe Caux, Julien C. Marie, Annabelle Cesaro, Lilia Boucinha, Amiran Dzutsev, Jean-Philippe Rasigade, Ulrike Rothermel, Giorgio Trinchieri, Azzak Bentaher-Belaaouaj, Oana Dumitrescu, Morgan Grau, Michelina Plateroti, Clovis Bondu

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (41), pp.10404-10409. ⟨10.1073/pnas.1722372115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (41), pp.10404-10409. ⟨10.1073/pnas.1722372115⟩

International audience; Prominent changes in the gut microbiota (referred to as "dysbiosis") play a key role in the development of allergic disorders, but the underlying mechanisms remain unknown. Study of the delayed-type hypersensitivity (DTH) resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f72c638beb7102ea94a7542c3c80f63
https://hal.science/hal-02398995

Hematopoietic stem/progenitor cell transplantation recovers immune defects and prevents lymphomas in Atm-deficient mice.

Autor: de Oliveira BSP; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy.; Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, 00161, Rome, Italy., Giovinazzo A; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy., Putti S; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER-IMPC, Mouse Clinic-CNR, Monterotondo Scalo, 00015, Rome, Italy., Merolle M; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy.; Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, 00161, Rome, Italy., Orsini T; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER-IMPC, Mouse Clinic-CNR, Monterotondo Scalo, 00015, Rome, Italy., Tocchini-Valentini GD; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER-IMPC, Mouse Clinic-CNR, Monterotondo Scalo, 00015, Rome, Italy., Lancrin C; Epigenetics and Neurobiology Unit, European Molecular Biology Laboratory (EMBL), Monterotondo Scalo, 00015, Rome, Italy., Naro F; Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, 00161, Rome, Italy., Pellegrini M; Institute of Biochemistry and Cell Biology (IBBC- CNR), Via Ercole Ramarini, 32 Monterotondo Scalo, 00015, Rome, Italy. manuela.pellegrini@cnr.it.

Publikováno v: Experimental hematology & oncology [Exp Hematol Oncol] 2024 Aug 06; Vol. 13 (1), pp. 81. Date of Electronic Publication: 2024 Aug 06.

The activity of a PI3K δ-sparing inhibitor, MEN1611, in non-small cell lung cancer cells with constitutive activation of the PI3K/AKT/mTOR pathway.

Autor: Papoff G; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Presutti D; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Fustaino V; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Parente A; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Calandriello C; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Alemà S; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Scavizzi F; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic, IBBC-CNR, Monterotondo, Rome, Italy., Raspa M; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic, IBBC-CNR, Monterotondo, Rome, Italy., Merlino G; Menarini Ricerche S.p.A., Rome, Italy., Salerno M; Menarini Ricerche S.p.A., Rome, Italy., Bigioni M; Menarini Ricerche S.p.A., Rome, Italy., Binaschi M; Menarini Ricerche S.p.A., Rome, Italy., Ruberti G; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Nov 14; Vol. 13, pp. 1283951. Date of Electronic Publication: 2023 Nov 14 (Print Publication: 2023).

Three-Dimensional X-ray Imaging of β-Galactosidase Reporter Activity by Micro-CT: Implication for Quantitative Analysis of Gene Expression.

Autor: Ermakova O; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Orsini T; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Fruscoloni P; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Chiani F; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Gambadoro A; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Putti S; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Cirilli M; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Mezzi A; Institute for the Study of Nanostructured Materials, ISMN-CNR, Monterotondo Staz., 00015 Rome, Italy., Kaciulis S; Institute for the Study of Nanostructured Materials, ISMN-CNR, Monterotondo Staz., 00015 Rome, Italy., Pasquini M; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Raspa M; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Scavizzi F; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.; Adriano Buzzati-Traverso Campus, Institute of Biochemistry and Cell Biology (IBBC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo Scalo, 00015 Rome, Italy., Tocchini-Valentini GP; Adriano Buzzati-Traverso Campus, European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR), Via Ramarini, 32, Monterotondo, 00015 Rome, Italy.

Publikováno v: Brain sciences [Brain Sci] 2021 Jun 04; Vol. 11 (6). Date of Electronic Publication: 2021 Jun 04.