Zobrazeno 1 - 2
of 2
pro vyhledávání: '"etiology [Tauopathies]"'
Autor:
Sandra E. Encalada, Biao Li, Edgar Gutierrez, Eva-Maria Mandelkow, Mihir Vohra, David Soriano-Castell, Aimee W. Kao, Frank J.A. Dennissen, Juan A. Oses-Prieto, Austin L Wang, Dominique A. Salazar, Miguel Alves-Ferreira, Sean D. Mooney, Victoria J. Butler, Kaveh Ashrafi, Alma L. Burlingame, Kathy H. Li, Beibei Jing, Alex Groisman
Publikováno v:
Human molecular genetics, vol 28, iss 9
Human Molecular Genetics
Human molecular genetics 28(9), 1498-1514 (2018). doi:10.1093/hmg/ddy442
Human Molecular Genetics
Human molecular genetics 28(9), 1498-1514 (2018). doi:10.1093/hmg/ddy442
Mutations in the microtubule-associated protein tau (MAPT) underlie multiple neurodegenerative disorders, yet the pathophysiological mechanisms are unclear. A novel variant in MAPT resulting in an alanine to threonine substitution at position 152 (A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2fd562da33ba17969c5f579e917b05
https://escholarship.org/uc/item/18w0z80x
https://escholarship.org/uc/item/18w0z80x
Autor:
Enrico Schmidt, Chronis Fatouros, Sandhya P. Koushika, Ghulam Jeelani Pir, Ralf Baumeister, Jacek Biernat, Eckhard Mandelkow, Eva-Maria Mandelkow
Publikováno v:
Human molecular genetics 21(16), 3587-3603 (2012). doi:10.1093/hmg/dds190
Human Molecular Genetics
Human Molecular Genetics; Vol 21
Human Molecular Genetics
Human Molecular Genetics; Vol 21
Increased Tau protein amyloidogenicity has been causatively implicated in several neurodegenerative diseases, collectively called tauopathies. In pathological conditions, Tau becomes hyperphosphorylated and forms intracellular aggregates. The deletio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8cf6ccbf1760ee4a1f7b27fdf94162