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pro vyhledávání: '"etiology/genetics/metabolism/therapy, Phospholipase D"'
Autor:
Cassese A, RACITI GA, Fiory F, Nigro C, Ulianich L, Castanò I, D'Esposito V, Terracciano D, Pastore L, Formisano P, Beguinot F, Miele C, CA and RGA contributed equally to this work.
Publikováno v:
PLoS ONE; Vol 8
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e60555 (2013)
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e60555 (2013)
Over-expression of phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes (PED/PEA-15) causes insulin resistance by interacting with the D4 domain of phospholipase D1 (PLD1). Indeed, the disruption of this association restores insu