Výsledky vyhledávání - "et Isabelle Bécam"

High hedgehog signaling is transduced by a multikinase-dependent switch controlling the apico-basal distribution of the GPCR smoothened

Autor: Marina Gonçalves-Antunes, Matthieu Sanial, Vincent Contremoulins, Sandra Carvalho, Anne Plessis, et Isabelle Bécam

Publikováno v: eLife. 11

SUMMARYThe oncogenic GPCR Smoothened is a key transducer of the Hedgehog morphogen, which plays essential roles in the patterning of epithelial structures. Here, we examine how Hedgehog controls Smoothened subcellular localization and activity in a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c63ffc95e45a137c76cb3a44da4f5e
https://pubmed.ncbi.nlm.nih.gov/36083801

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