Zobrazeno 1 - 10
of 740
pro vyhledávání: '"estrogen signaling"'
Autor:
Patryk Janus, Paweł Kuś, Roman Jaksik, Natalia Vydra, Agnieszka Toma-Jonik, Michalina Gramatyka, Monika Kurpas, Marek Kimmel, Wiesława Widłak
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Transforming growth factor beta (TGFβ) is important for the morphogenesis and secretory function of the mammary gland. It is one of the main activators of the epithelial–mesenchymal transition (EMT), a process important for tis
Externí odkaz:
https://doaj.org/article/a070ecc223954c4bbfcafdeb17507231
Autor:
Annamaria Salvati, Giorgio Giurato, Jessica Lamberti, Ilaria Terenzi, Laura Crescenzo, Viola Melone, Luigi Palo, Alessandro Giordano, Francesco Sabbatino, Giuseppina Roscigno, Cristina Quintavalle, Gerolama Condorelli, Francesca Rizzo, Roberta Tarallo, Giovanni Nassa, Alessandro Weisz
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Identifying master epigenetic factors controlling proliferation and survival of cancer cells allows to discover new molecular targets exploitable to overcome resistance to current pharmacological regimens. In breast cancer (BC), resistance t
Externí odkaz:
https://doaj.org/article/c02e9b5b03f246858d4207d54d783e59
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by abnormal steroid hormone levels in peripheral blood and poor-quality oocytes. In the ovary, androgen is produced by theca cells, and estrogen is produced by granulosa cells. A
Externí odkaz:
https://doaj.org/article/cb8f66d39afe4ac7a4239a691a112ee4
Autor:
Yanfeng Xue, Yingyun Gong, Xin Li, Fei Peng, Guolian Ding, Zhao Zhang, Junchao Shi, Ilma Saleh Savul, Yong Xu, Qi Chen, Leng Han, Shengyong Mao, Zheng Sun
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Background Gene-environment interactions contribute to metabolic disorders such as diabetes and dyslipidemia. In addition to affecting metabolic homeostasis directly, drugs and environmental chemicals can cause persistent alterations in meta
Externí odkaz:
https://doaj.org/article/9e1f725e95d74bf88e0462cd0ae2f4de
Autor:
Haitao Nie, Yunlu Xu, Yuqian Zhang, Yue Wen, Jixiang Zhan, Yong Xia, Yongkang Zhou, Renping Wang, Xiaobing Wu
Publikováno v:
BMC Zoology, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Background The precise mechanisms of hormone action responsible for the full course of events modulating folliculogenesis in crocodilian have not been determined, although histological features have been identified. Results The Alligator sin
Externí odkaz:
https://doaj.org/article/cb0fe06eea3f4f5bb9f7e2f18311c313
Autor:
Hao Yu, Anas M Khanshour, Aki Ushiki, Nao Otomo, Yoshinao Koike, Elisabet Einarsdottir, Yanhui Fan, Lilian Antunes, Yared H Kidane, Reuel Cornelia, Rory R Sheng, Yichi Zhang, Jimin Pei, Nick V Grishin, Bret M Evers, Jason Pui Yin Cheung, John A Herring, Chikashi Terao, You-qiang Song, Christina A Gurnett, Paul Gerdhem, Shiro Ikegawa, Jonathan J Rios, Nadav Ahituv, Carol A Wise
Publikováno v:
eLife, Vol 12 (2024)
Adolescent idiopathic scoliosis (AIS) is a common and progressive spinal deformity in children that exhibits striking sexual dimorphism, with girls at more than fivefold greater risk of severe disease compared to boys. Despite its medical impact, the
Externí odkaz:
https://doaj.org/article/008395c97b104a1f9a8bdc58a295796f
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 915-930 (2023)
Krüppel-like factor 10 (KLF10), also known as TGFβ-inducible early gene-1 (TIEG1), was first found in human osteoblasts. Early studies show that KLF10 plays an important role in osteogenic differentiation. Through decades of research, KLF10 has bee
Externí odkaz:
https://doaj.org/article/13aa36b12de7477c9485e708ee57d72d
Autor:
Jennifer M. McCracken, Gisele A. Calderon, Quynh N. Le, Natasha M. Faruqui, Swathi Balaji, Julie C. E. Hakim
Publikováno v:
Physiological Reports, Vol 11, Iss 15, Pp n/a-n/a (2023)
Abstract Loss of estrogen as a result of aging, pelvic cancer therapy, genetics, or eating disorders affects numerous body systems including the reproductive tract. Specifically, a chronic hypoestrogenic state fosters debilitating vaginal symptoms li
Externí odkaz:
https://doaj.org/article/b84e1a615220469196e280b284171321
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