Zobrazeno 1 - 10
of 1 923
pro vyhledávání: '"essential genes"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3081-3089 (2024)
Detailed explorations of the model organisms Caenorhabditis elegans (elegant worm) and Drosophila melanogaster (vinegar fly) have substantially improved our knowledge and understanding of biological processes and pathways in metazoan organisms. Exten
Externí odkaz:
https://doaj.org/article/937c74c759464ab6b630662bd2744f4f
Autor:
Chaoyue Pang, Ling Jin, Haoyu Zang, Damalk Saint-Claire S. Koklannou, Jiazhi Sun, Jiawei Yang, Yongxing Wang, Liang Xu, Chunyan Gu, Yang Sun, Xing Chen, Yu Chen
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 5, Pp 1580-1592 (2024)
Xanthomonas spp. cause severe bacterial diseases. However, effective strategies for prevention and management of these diseases are scarce. Thus, it is necessary to improve the efficiency of control of diseases caused by Xanthomonas. In this study, X
Externí odkaz:
https://doaj.org/article/e1e243734b994f27a950f6583516c233
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Essential genes encode functions that play a vital role in the life activities of organisms, encompassing growth, development, immune system functioning, and cell structure maintenance. Conventional experimental techniques for ide
Externí odkaz:
https://doaj.org/article/0b5f438f6c30445fb1a98e4415b135eb
Akademický článek
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Autor:
Thomas Jebastin, M.H. Syed Abuthakir, Ilangovan Santhoshi, Muniraj Gnanaraj, Mansour K. Gatasheh, Anis Ahamed, Velusamy Sharmila
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31713- (2024)
Humans benefit from a vast community of microorganisms in their gastrointestinal tract, known as the gut microbiota, numbering in the tens of trillions. An imbalance in the gut microbiota known as dysbiosis, can lead to changes in the metabolite prof
Externí odkaz:
https://doaj.org/article/503710f8f3474f3abe5c76db93637a61
Autor:
Basharat Bashir Teli, Priyanka Nagar, Yumnam Priyadarshini, Poonam Poonia, Krishnamurthy Natarajan
Publikováno v:
mSphere, Vol 9, Iss 2 (2024)
ABSTRACT Promoter shutoff of essential genes in the diploid Candida albicans has often been insufficient to create tight, conditional null alleles due to leaky expression and has been a stumbling block in pathogenesis research. Moreover, homozygous d
Externí odkaz:
https://doaj.org/article/965e675b955b45e7ae80234183fee729
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Sinorhizobium fredii CCBAU45436 is an excellent rhizobium that plays an important role in agricultural production. However, there still needs more comprehensive understanding of the metabolic system of S. fredii CCBAU45436, which hinders its applicat
Externí odkaz:
https://doaj.org/article/3833c940447941d1aade7ed21a5eaed4
Publikováno v:
iMeta, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Over the past few decades, there has been a significant interest in the study of essential genes, which are crucial for the survival of an organism under specific environmental conditions and thus have practical applications in the fields of
Externí odkaz:
https://doaj.org/article/51c62d967c78433282fecd6ca1081081
Autor:
Wendy E. Geslewitz, Amaris Cardenas, Xufei Zhou, Yan Zhang, Alison K. Criss, H Steven Seifert
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR) are prokaryotic adaptive immune systems regularly utilized as DNA-editing tools. While Neisseria gonorrhoeae does not have an endogenous CRISPR, the commensal species Neisser
Externí odkaz:
https://doaj.org/article/652a190888264f12aa9ed567d9bab8d5
Autor:
Kira S. Makarova, Changyi Zhang, Yuri I. Wolf, Svetlana Karamycheva, Rachel J. Whitaker, Eugene V. Koonin
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT The identification of microbial genes essential for survival as those with lethal knockout phenotype (LKP) is a common strategy for functional interrogation of genomes. However, interpretation of the LKP is complicated because a substantial
Externí odkaz:
https://doaj.org/article/cb5d368cfa5e4f78a90c28049878ebbc