Zobrazeno 1 - 10
of 431
pro vyhledávání: '"escape mutations"'
Autor:
Bayraktar C, Kayabolen A, Odabas A, Durgun A, Kok I, Sevinc K, Supramaniam A, Idris A, Bagci-Onder T
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 6931-6943 (2024)
Canan Bayraktar,1,* Alisan Kayabolen,1,* Arda Odabas,1 Aysegul Durgun,1 Ipek Kok,1 Kenan Sevinc,1 Aroon Supramaniam,2 Adi Idris,2,3 Tugba Bagci-Onder1 1Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Ista
Externí odkaz:
https://doaj.org/article/e67c3d19165842a081fd1982b062860f
Publikováno v:
mLife, Vol 3, Iss 1, Pp 119-128 (2024)
Abstract Saccharolobus islandicus REY15A represents one of the very few archaeal models with versatile genetic tools, which include efficient genome editing, gene silencing, and robust protein expression systems. However, plasmid vectors constructed
Externí odkaz:
https://doaj.org/article/15d3d903b0a74ec8aad69b5c0d06527c
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 1, Pp 26-31 (2024)
Objective To investigate asymptomatic infection of hepatitis B virus(HBV) among hepatitis B vaccinated donors in Shenzhen, and analyze its serological and molecular characteristics. Methods The HBsAg ELISA positive blood samples of blood donors born
Externí odkaz:
https://doaj.org/article/037e3406179d480e96996c091adc4bad
Akademický článek
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Autor:
Bonolo B. Phinius, Wonderful T. Choga, Motswedi Anderson, Margaret Mokomane, Irene Gobe, Tsholofelo Ratsoma, Basetsana Phakedi, Gorata Mpebe, Lynnette Bhebhe, Tendani Gaolathe, Mosepele Mosepele, Joseph Makhema, Roger Shapiro, Shahin Lockman, Rosemary Musonda, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1561 (2024)
(1) Background: Hepatitis B virus (HBV) sequencing data are important for monitoring HBV evolution. We aimed to molecularly characterize HBV sequences from participants with HBV surface antigen-positive (HBsAg+) serology and occult hepatitis B infect
Externí odkaz:
https://doaj.org/article/6829cfe2e45447ae99c2e3fcd79459a4
Autor:
T.A.L. Balde, Yulia V. Ostankova, S. Boumbaly, Ekaterina V. Naidenova, Elena B. Zueva, Elena N. Serikova, Diana E. Valutite, Alexander N. Schemelev, Vladimir S. Davydenko, Elena V. Esaulenko, Areg A. Totolian
Publikováno v:
Вопросы вирусологии, Vol 68, Iss 3, Pp 228-241 (2023)
The aim of the work is to assess the prevalence of hepatitis B virus drug resistance mutations and immune escape mutations in pregnant women in the Republic of Guinea. Materials and methods. Blood plasma samples obtained from 480 pregnant women fr
Externí odkaz:
https://doaj.org/article/8667ba2aaf8c419f937071243bfff570
Autor:
Lorenzo Piermatteo, Stefano D’Anna, Ada Bertoli, Maria Bellocchi, Luca Carioti, Lavinia Fabeni, Mohammad Alkhatib, Simone La Frazia, Miriam Lichtner, Claudio Mastroianni, Giuseppe De Sanctis, Massimo Marignani, Caterina Pasquazzi, Nerio Iapadre, Giustino Parruti, Giuseppina Cappiello, Jacopo Vecchiet, Vincenzo Malagnino, Sandro Grelli, Francesca Ceccherini-Silbertein, Massimo Andreoni, Loredana Sarmati, Valentina Svicher, Romina Salpini
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTSpecific HBsAg mutations are known to hamper HBsAg recognition by neutralizing antibodies thus challenging HBV-vaccination efficacy. Nevertheless, information on their impact and spreading over time is limited. Here, we characterize the circu
Externí odkaz:
https://doaj.org/article/1b43cf2280ad42c3a779f94d738ea759
Autor:
Steven C. Holland, LaRinda A. Holland, Matthew F. Smith, Mihyun B. Lee, James C. Hu, Efrem S. Lim
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve, mutations arise that will allow the virus to evade immune defenses and therapeutics. Assays that can identify these mutations can be used to guide personali
Externí odkaz:
https://doaj.org/article/8ab13a3cb20f40ae99aa1f1aab1aa0b3
Autor:
Dominique Fournelle, Fatima Mostefai, Elsa Brunet-Ratnasingham, Raphaël Poujol, Jean-Christophe Grenier, José Héctor Gálvez, Amélie Pagliuzza, Inès Levade, Sandrine Moreira, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Gabrielle Gendron-Lepage, Catherine Bourassa, Alexandra Tauzin, Simon Grandjean Lapierre, Nicolas Chomont, Andrés Finzi, Daniel E. Kaufmann, Morgan Craig, Julie G. Hussin
Publikováno v:
Viruses, Vol 16, Iss 3, p 342 (2024)
Throughout the SARS-CoV-2 pandemic, several variants of concern (VOCs) have been identified, many of which share recurrent mutations in the spike glycoprotein’s receptor-binding domain (RBD). This region coincides with known epitopes and can theref
Externí odkaz:
https://doaj.org/article/b58d204029254f828a03d44fc75a441d
Autor:
Oguntope Adeorike Sobajo, Judith Uche Oguzie, Benjamin Adegboyega, Philomena Eromon, Christian Happi, Isaac Komolafe, Onikepe Folarin
Publikováno v:
Viruses, Vol 15, Iss 11, p 2188 (2023)
Several mutations in the surface (S), basal core promoter (BCP), and precore (PC) genes of the hepatitis B virus have been linked to inaccurate diagnosis and the development of immune escape mutants (IEMs) of the infection, which can lead to chronic
Externí odkaz:
https://doaj.org/article/8f9f2bfadcfa4766adeece34e39ffed2