Zobrazeno 1 - 10
of 2 011
pro vyhledávání: '"esat-6"'
Autor:
Timothy A Bates, Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka, Shandee D Dixon, Anthony Shumate, Abigail R Groncki, Matthew AH Parson, Jessica R Ingram, Eric Barklis, John E Burke, Ujwal Shinde, Hidde L Ploegh, Fikadu G Tafesse
Publikováno v:
eLife, Vol 12 (2024)
Mycobacterium tuberculosis (Mtb) is known to survive within macrophages by compromising the integrity of the phagosomal compartment in which it resides. This activity primarily relies on the ESX-1 secretion system, predominantly involving the protein
Externí odkaz:
https://doaj.org/article/02546070fb4649659e3251bb6aab7254
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29251- (2024)
Objective: To assess the diagnostic value of immunohistochemical (IHC) staining for detecting the tuberculosis-secreted antigens ESAT-6 and CFP10 in lymph node tuberculosis. Methods: Archived, paraffin-embedded lymph node specimens from 72 patients d
Externí odkaz:
https://doaj.org/article/5134a4883c41421c9d688ab941857724
Autor:
Beatriz B. S. Passos, Mariana Araújo-Pereira, Caian L. Vinhaes, Eduardo P. Amaral, Bruno B. Andrade
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite major global efforts to eliminate tuberculosis, which is caused by Mycobacterium tuberculosis (Mtb), this disease remains as a major plague of humanity. Several factors associated with the host and Mtb interaction favor the infection establis
Externí odkaz:
https://doaj.org/article/6543f0be09444fa68bfa19fe64201459
Autor:
Zhandos Abay, Sandugash Sadikalieva, Kamshat Shorayeva, Bolat Yespembetov, Makpal Sarmykova, Kuanish Jekebekov, Gaukhar Tokkarina, Zharkinay Absatova, Elina Kalimolda, Yeraly Shayakhmetov, Sabina Moldagulova, Aisha Issabek, Syrym Kopeyev, Alisher Omurtay, Kainar Barakbayev, Markhabat Kassenov, Nazym Syrym, Yergali Abduraimov, Kunsulu Zakarya, Ainur Nurpeisova
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-7 (2023)
Abstract Background Bovine Tuberculosis is a respiratory disease caused by the pathogen Mycobacterium bovis (M. bovis) that infects cattle. Though rare, this disease can also affect humans, as well as domestic and wild animals, making it a serious co
Externí odkaz:
https://doaj.org/article/8330f024ea054be384f6168222e9d6be
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1151 (2024)
The Esx-1 family proteins of the Type VII secretion systems of Mycobacterium bovis and Mycobacterium tuberculosis have been assessed and are frequently used as candidates for tuberculosis (TB) diagnosis in both humans and animals. The presence of ESA
Externí odkaz:
https://doaj.org/article/9cd3189ae85f43c38b88a7d0e38619c5
Autor:
Owen A. Collars, Bradley S. Jones, Daniel D. Hu, Simon D. Weaver, Taylor A. Sherman, Matthew M. Champion, Patricia A. Champion
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT N-terminal protein acetylation is a ubiquitous post-translational modification that impacts diverse cellular processes in higher organisms. Bacterial proteins are also N-terminally acetylated, but the mechanisms and consequences of this modi
Externí odkaz:
https://doaj.org/article/3da7bd96f9d04bb2a861ece31401ffc4
Akademický článek
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Autor:
Dmitry A. Kudlai, N. P. Doktorova
Publikováno v:
Инфекция и иммунитет, Vol 12, Iss 3, Pp 439-449 (2022)
Recombinant technologies have been long widely used in medicine. This article presents a review on the application of medical technologies based on ESAT-6 and CFP-10 proteins in diagnostics and prevention of tuberculosis. ESAT-6 and CFP-10 are specif
Externí odkaz:
https://doaj.org/article/75e4b803bc104b1d935872e0def5304a
Autor:
Jinjie Yu, Xueting Fan, Xiuli Luan, Ruihuan Wang, Bin Cao, Chengyu Qian, Guilian Li, Machao Li, Xiuqin Zhao, Haican Liu, Kanglin Wan, Xiuqin Yuan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tuberculosis (TB) is an infectious disease that seriously affects human health. Until now, the only anti-TB vaccine approved for use is the live attenuated Mycobacterium bovis (M. bovis) vaccine — BCG vaccine, but its protective efficacy is relativ
Externí odkaz:
https://doaj.org/article/00b01d1b1da1488b8423119436efd077
Akademický článek
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