Zobrazeno 1 - 10
of 92 533
pro vyhledávání: '"erk"'
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Hypertension is associated with poor outcome and higher mortality in patients with ischemic stroke. The impairment of adaptive vascular mechanisms under hypertensive condition compromises collateral blood flow after arterial occlusion in pat
Externí odkaz:
https://doaj.org/article/09f2f0b03e994392b0a1ce906ef72f62
Autor:
Jinhong Chen, Xiaoyu Geng, Bingbing Li, Jinyao Xie, Jieying Ma, Zhen Qin, Mingke Wang, Jishun Yang
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11630-11645 (2024)
Metamorphosis control is pivotal in preventing the outbreak of jellyfish, and it is often studied using common model organisms. The widespread use of the ultraviolet blocking agent homosalate in cosmetics poses a threat to marine ecosystems. Although
Externí odkaz:
https://doaj.org/article/9ba8b26f02e34d13aa577d5c2d186a75
Autor:
Haiping Liu, Limin Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Objective To explore the mechanism of action of MicroRNAs-34a (miR-34a) and Eurite growth guiding factor 1 (Netrin1) in cisplatin resistance in gastric cancer (GC), providing new clues for overcoming tumor resistance and optimizing anti-tumo
Externí odkaz:
https://doaj.org/article/42ecb4f15d1c43a7b02eb07d4d9402c7
Autor:
Wei Xiong, Ya Xie, Dong Wang, Xiaozhi Huang, Xiaohui Hao, Jianming Liu, Xiaohui Liu, Xiaobin Gu, Shaoqian Sun, Yufeng Li, Jingwu Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Aldo-keto reductase family 1 member C3 (AKR1C3) is a radioresistance gene in esophageal cancer. This study aimed to investigate the signaling pathways that mediate the regulatory role of AKR1C3 in the radioresistance of esophageal
Externí odkaz:
https://doaj.org/article/01c4ce5e4a9a4676a8d7187d33aa6ad9
Publikováno v:
Journal of the Egyptian National Cancer Institute, Vol 36, Iss 1, Pp 1-12 (2024)
Abstract Background Regulatory mechanism of ERK1 and ERK2, their mechanisms of action, and how they impact on development, growth, and homeostasis of different organisms have been given much emphasis for long. ERK1 and 2 though are isoforms of ERK mi
Externí odkaz:
https://doaj.org/article/5e6f6beb4c3d4443b53600a0d9bcb7d3
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract This study aimed to investigate the effect and potential mechanism of evodiamine (EVO) on proliferation and apoptosis of nasopharyngeal carcinoma (NPC) cells. EVO inhibited proliferation, blocked cell cycle progression, and induced apoptosis
Externí odkaz:
https://doaj.org/article/dd9d35a2b116443c996e01e325c16baa
Autor:
Hongjie He, Kexian Dong, Mingming Chen, Yuanyuan Wang, Yawen Li, Dong Wang, Mansha Jia, Xiangning Meng, Wenjing Sun, Songbin Fu, Jingcui Yu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Gastric cancer is one of the most malignant digestive tract tumors worldwide and its progression is associated with gene expression and metabolic alteration. We revealed that the gastric cancer patients with lower expression level of TOB1 ex
Externí odkaz:
https://doaj.org/article/ff0a2496c6b147ca82ec3f9e13a5b941
Autor:
Francesca Giammello, Chiara Biella, Erica Cecilia Priori, Matilde Amat Di San Filippo, Roberta Leone, Francesca D’Ambrosio, Martina Paterno’, Giulia Cassioli, Antea Minetti, Francesca Macchi, Cristina Spalletti, Ilaria Morella, Cristina Ruberti, Beatrice Tremonti, Federica Barbieri, Giuseppe Lombardi, Riccardo Brambilla, Tullio Florio, Rossella Galli, Paola Rossi, Federico Brandalise
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-28 (2024)
Abstract Background Glioblastoma (GBM) stands as the most prevalent and aggressive form of adult gliomas. Despite the implementation of intensive therapeutic approaches involving surgery, radiation, and chemotherapy, Glioblastoma Stem Cells contribut
Externí odkaz:
https://doaj.org/article/f620b5142f8b4c7d9c81860a86cd23a7
Publikováno v:
Open Veterinary Journal, Vol 14, Iss 8, Pp 1836-1842 (2024)
Background: Hypercholesterolemia is frequently linked to an elevated risk of cardiovascular diseases, including heart attacks and strokes. Additionally, it could be connected to a higher susceptibility to osteoporosis. Hypercholesterolemia can stimul
Externí odkaz:
https://doaj.org/article/8662ef656ecb4fd2b9bc387ccf35fd38
Autor:
Kesheng Li, Dandan Chai, Shiyang Ren, Xiaowen Lian, Xiaoling Shi, Yang Xu, Lie Bao, Suisheng Yang, Yurong Liang, Xiaoqin Li, Huifen Du
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Our previous study demonstrated that β2-microglobulin (β2M) promoted ER+/HER2– breast cancer survival via the SGK1/Bcl-2 signaling pathway. However, the role of β2M has not been investigated in ER–/HER2+ breast cancer. Here
Externí odkaz:
https://doaj.org/article/c9007b550ae04b5b939397f324d7d403