Zobrazeno 1 - 10
of 5 342
pro vyhledávání: '"erbb2"'
Autor:
Sounetra Choudhury, Sandip Ghosh, Prosenjeet Chakraborty, Sayari Pal, Koustuv Ghosh, Subhankar Saha, Jitesh Midha, Vinu Sankar, Abhisek Mohata, Bitan Kumar Chattopadhyay, Shibajyoti Ghosh, Soumen Das, Biswarup Basu, Nilabja Sikdar
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background and introduction Two and half percent of the Indian population suffer from gallbladder cancer (GBC). The primary factors that lead GBC are associated with mutation of several protooncogenes such as EGFR, ERBB2, Myc, and CCND1 alon
Externí odkaz:
https://doaj.org/article/2851fcba53e8421e8e44c2d035b5daa0
Autor:
Julien Corné, Véronique Quillien, Florence Godey, Mathilde Cherel, Agathe Cochet, Fanny Le Du, Lucie Robert, Héloïse Bourien, Angélique Brunot, Laurence Crouzet, Christophe Perrin, Claudia Lefeuvre‐Plesse, Véronique Diéras, Thibault De la Motte Rouge
Publikováno v:
Molecular Oncology, Vol 18, Iss 11, Pp 2714-2729 (2024)
Erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐activating mutations are therapeutically actionable alterations found in various cancers, including metastatic breast cancer (MBC). We developed multiplex digital PCR assays to detect and quantify ERBB2 m
Externí odkaz:
https://doaj.org/article/d0a0f127e91c4930a10cc399be686cfa
Autor:
Melica Nourmoussavi Brodeur, Pier Selenica, Weining Ma, Sara Moufarrij, Christian Dagher, Thais Basili, Nadeem R. Abu‐Rustum, Carol Aghajanian, Qin Zhou, Alexia Iasonos, Lora H. Ellenson, Britta Weigelt, M. Herman Chui
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2356-2368 (2024)
Anti‐HER2 therapy is indicated for erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐amplified/overexpressing endometrial carcinoma (EC). Mutations constitute another mode of ERBB2 activation, but only rare ERBB2‐mutated ECs have been reported. We so
Externí odkaz:
https://doaj.org/article/5b6c7d7bf2c04f0080d4461d3815a0fb
Autor:
Wu-niri Gao, Li-gang Chen, Lu-ri Bao, Ning He, Ta-la Hu, Can Lai, Rui-feng Xu, Xi-feng Wang, Jing-yuan Wang, Jian-rong Zhao, Yan Meng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Renal clear cell carcinoma (ccRCC) is a common parenchymal tumor of the kidney, and the discovery of biomarkers for early and effective diagnosis of ccRCC can improve the early diagnosis of patients and thus improve long-term survival. Erb-b
Externí odkaz:
https://doaj.org/article/64b325e61bc648b9b1ec65607511370b
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract This study aimed to investigate the effect and potential mechanism of evodiamine (EVO) on proliferation and apoptosis of nasopharyngeal carcinoma (NPC) cells. EVO inhibited proliferation, blocked cell cycle progression, and induced apoptosis
Externí odkaz:
https://doaj.org/article/dd9d35a2b116443c996e01e325c16baa
Autor:
Haoyue Qin, Huan Yan, Yangqian Chen, Qinqin Xu, Zhe Huang, Wenjuan Jiang, Zhan Wang, Li Deng, Xing Zhang, Lin Zhang, Nong Yang, Liang Zeng, Yongchang Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Limited data exists on the efficacy of immune checkpoint inhibitor (ICI) combinations in non-small-cell lung cancer (NSCLC) with uncommon driver alterations in genes such as ERBB2, BRAF, RET, and MET. This study retrospectively as
Externí odkaz:
https://doaj.org/article/c41750fbe4b64c9eb1c84566a8bc7ed4
Publikováno v:
Exploration of Medicine, Vol 5, Iss 4, Pp 530-543 (2024)
Aim: Present study was done to understand the dimerization of HER2/ERBB2 in normal and cancer cells using in-silico study. Methods: Pathway analysis was done using Reactome. Structure of HER2/ERBB2 protein was obtained from PDB database, and using S
Externí odkaz:
https://doaj.org/article/99612d68797e495581bf802cdd603cd1
Autor:
Anahita Shirvani, Sheida Sabbagh Seddigh, Mahshid Haddad, Farzad Amiri, Faezeh Fattahi, Ebrahim Alipour Limaee
Publikováno v:
International Journal of Scientific Research in Dental and Medical Sciences, Vol 6, Iss 2, Pp 74-84 (2024)
Background and aim: Breast cancer is one of the most common and worrying health problems of women in the world. The efficacy and safety of first-line and second-line/next-line treatments in women with HR + / HER2 − postmenopausal advanced breast ca
Externí odkaz:
https://doaj.org/article/da912b72d4284e55821025524541e285
Autor:
Hiroshi Ichikawa, Kenji Usui, Masaki Aizawa, Yoshifumi Shimada, Yusuke Muneoka, Yosuke Kano, Mika Sugai, Kazuki Moro, Yuki Hirose, Kohei Miura, Jun Sakata, Hiroshi Yabusaki, Satoru Nakagawa, Takashi Kawasaki, Hajime Umezu, Shujiro Okuda, Toshifumi Wakai
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Evaluation of human epidermal growth factor receptor 2 (HER2) overexpression caused by erb-b2 receptor tyrosine kinase 2 (ERBB2) amplification (AMP) by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) is es
Externí odkaz:
https://doaj.org/article/58024c73781244c2a550d82427280eba
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 204-30 (2024)
Borderline ovarian tumours (BOTs) show intriguing characteristics distinguishing them from other ovarian tumours. The aim of the systematic review was to analyse the spectrum of molecular changes found in BOTs and discuss their significance in the co
Externí odkaz:
https://doaj.org/article/61b5980ba5e544b385458d81e31cafd0