Zobrazeno 1 - 10
of 80
pro vyhledávání: '"eprotirome"'
Autor:
Girish Raparti, Suyog Jain, Karuna Ramteke, Mangala Murthy, Ravi Ghanghas, Sunita Ramanand, Jaiprakash Ramanand
Publikováno v:
Indian Journal of Endocrinology and Metabolism, Vol 17, Iss 2, Pp 211-218 (2013)
Thyroid hormone (TH) is known to have many beneficial effects on vital organs, but its extrapolation to be used therapeutically has been restricted by the fact that it does have concurrent adverse effects. Recent finding of various thyroid hormone re
Externí odkaz:
https://doaj.org/article/bbf61fe492664f9191021ce5d80e9bf4
Autor:
Riccardo Zucchi
Publikováno v:
Thyroid
The development of thyroid hormone (TH) analogues was prompted by the attempt to exploit the effects of TH on lipid metabolism, avoiding cardiac thyrotoxicosis. Analysis of the relative distribution of the α and β subtypes of nuclear TH receptors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c51a9bbe21a0af205ba22142d7fcf85
http://hdl.handle.net/11568/1059070
http://hdl.handle.net/11568/1059070
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 7 (2020)
Frontiers in Medicine, Vol 7 (2020)
Thyroid hormones (THs) elicit significant effects on numerous physiological processes, such as growth, development, and metabolism. A lack of thyroid hormones is not compatible with normal health. Most THs effects are mediated by two different thyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2d71d80f75ff65059e2938cc374dee
https://pubmed.ncbi.nlm.nih.gov/32733906
https://pubmed.ncbi.nlm.nih.gov/32733906
The Side Effects of Drugs Annuals is a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: The International Encyclopedia of Advers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e94f6ec11b73e728486a9d8c2bef6869
https://doi.org/10.1016/bs.seda.2020.07.003
https://doi.org/10.1016/bs.seda.2020.07.003
Autor:
John J.P. Kastelein, Bregje van Zaane, G. Kees Hovingh, Laura P. B. Elbers, Victor E. A. Gerdes, Barbara Sjouke
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific reports, 7(1):14174. Nature Publishing Group
Scientific Reports
Scientific reports, 7(1):14174. Nature Publishing Group
Scientific Reports
Eprotirome, a liver specific thyroid hormone agonist, was shown to induce significant increases in markers of liver injury along with a modest decrease in atherogenic lipids and lipoproteins. To get more insight into whether these effects on liver pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a722405d897077068c4cc47ef82436a8
http://link.springer.com/article/10.1038/s41598-017-14526-2
http://link.springer.com/article/10.1038/s41598-017-14526-2
Autor:
Amedeo Columbano, Marta Szydlowska, Giovanna M. Ledda-Columbano, Sandra Mattu, Elisabetta Puliga, Andrea Perra, Vera Piera Leoni, Monica Pibiri
Publikováno v:
Gene Expression. 17:207-218
Although the hepatomitogenic activity of T3 is well established, the wide range of harmful effects exerted by this hormone precludes its use in regenerative therapy. The aim of this study was to investigate whether an agonist of TRβ, KB2115 (Eprotir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a43d1d2029ab22b82539eaf844a1f8
https://doi.org/10.3727/105221617x695438
https://doi.org/10.3727/105221617x695438
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2408-2415 (2014)
Journal of Lipid Research
Journal of Lipid Research
Reduced plasma LDL-cholesterol is a hallmark of hyperthyroidism and is caused by transcriptional stimulation of LDL receptors in the liver. Here, we investigated whether thyroid hormone (TH) actions involve other mechanisms that may also account for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7e5e10acd36fe0de625db2b14d2b31
http://www.sciencedirect.com/science/article/pii/S0022227520349920
http://www.sciencedirect.com/science/article/pii/S0022227520349920
Autor:
Michael Soeberdt, Jérémy Chéret, J. Gherardini, Tamás Bíró, L. Ponce, Ralf Paus, Jennifer E. Kloepper, Attila Oláh, Christoph Abels, Marta Bertolini
Publikováno v:
Journal of Investigative Dermatology. 136:1711-1714
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d10395240921a6c0d4f470de9e8aa62
https://doi.org/10.1016/j.jid.2016.03.033
https://doi.org/10.1016/j.jid.2016.03.033
Autor:
Jan Lammel Lindemann, Paul Webb
Publikováno v:
Expert Opinion on Therapeutic Targets. 20:145-149
Sobetirome binds selectively to the main hepatic form of thyroid hormone (TH) receptor, TRβ1, compared to TRα1, which is principally responsible for thyrotoxic effects on heart, muscle and bone. Sobetirome also preferentially accumulates in liver.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897ec2ea7a0ef31263ab375c4cc46375
https://doi.org/10.1517/14728222.2016.1090429
https://doi.org/10.1517/14728222.2016.1090429
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