Zobrazeno 1 - 10
of 267
pro vyhledávání: '"eplet"'
Autor:
Lisa Kleid, Julia Walter, Patrick Moehnle, Christian Wichmann, Julia Kovács, Andreas Humpe, Christian Schneider, Sebastian Michel, Nikolaus Kneidinger, Michael Irlbeck, Jan Fertmann, Andrea Dick, Teresa Kauke
Publikováno v:
Transplant International, Vol 37 (2024)
Human leukocyte antigen (HLA) mismatches (MM) between donor and recipient lead to eplet MM (epMM) in lung transplantation (LTX), which can induce the development of de-novo donor-specific HLA-antibodies (dnDSA), particularly HLA-DQ-dnDSA. Aim of our
Externí odkaz:
https://doaj.org/article/6dd7f25a89eb4fa893ba7310fe938a4e
Autor:
Jenny Tran, Ibrahim Alrajhi, Doris Chang, Karen R. Sherwood, Paul Keown, Jagbir Gill, Matthew Kadatz, John Gill, James H. Lan
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The optimal immunosuppression management in patients with a failed kidney transplant remains uncertain. This study analyzed the association of class II HLA eplet mismatches and maintenance immunosuppression with allosensitization after graft failure
Externí odkaz:
https://doaj.org/article/ca1d2fe3320c4acba795755db0bc3a8f
Autor:
Katarzyna Stefańska, Małgorzata Kurkowiak, Karolina Piekarska, Elżbieta Chruściel, Dorota Zamkowska, Joanna Jassem-Bobowicz, Przemysław Adamski, Renata Świątkowska-Stodulska, Anna Abacjew-Chmyłko, Katarzyna Leszczyńska, Maciej Zieliński, Krzysztof Preis, Hanna Zielińska, Bogusław Tymoniuk, Piotr Trzonkowski, Natalia Maria Marek-Trzonkowska
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPreeclampsia is responsible for more than 70 000 and 500 000 maternal and fetal deaths, respectively each year. Incomplete remodelling of the spiral arteries in placenta is the most accepted theory of preeclampsia pathogenesis. However, t
Externí odkaz:
https://doaj.org/article/aebcbb608f8a41dc8dcbb63964485d75
Autor:
Oguz Fatma Savran, Oguz Suleyman Rustu, Ogret Yeliz, Karadeniz Tanju Sedat, Ciftci Hayriye Senturk, Karatas Sule, Kivanc Demet, Aydin Filiz
Publikováno v:
Türk Biyokimya Dergisi, Vol 47, Iss 3, Pp 289-295 (2022)
The antibodies interact with the “Human Leukocyte Antigen (HLA) antigens” at specific epitopes. “Epitopes” are present on a single HLA or shared by multiple antigens. In this study, we aim to determine the frequency of prevalent epitopes comm
Externí odkaz:
https://doaj.org/article/84c8f8b28dc1444eb2f5825b10987023
Publikováno v:
Zhongguo shuxue zazhi, Vol 35, Iss 9, Pp 907-910 (2022)
Objective To analyze the specificity and Eplets of HLA allele-specific antibody in patients with platelet transfusion refractoriness (PTR). Methods HLA-A and B genotypes were detected by PCR-SBT, and HLA-Ⅰ antibodies in patients′ serum were detec
Externí odkaz:
https://doaj.org/article/feb588856ad44cab934f9abf1d0417fb
Publikováno v:
Canadian Journal of Bioethics, Vol 6, Iss 2 (2023)
Precision medicine can put clinicians in a position where they must act more as resource allocators than their traditional role as patient advocates. In the allocation of transplantable organs and tissues, the use of eplet matching will enhance preci
Externí odkaz:
https://doaj.org/article/94698bc58c7f40d48b58c8346a00d193
Autor:
Elena González-López, Javier Gonzalo Ocejo-Vinyals, Mónica Renuncio-García, Adriel Roa-Bautista, David San Segundo Arribas, Clara Escagedo, María del Mar García-Saiz, Rosalía Valero, Pilar García-Berbel, Juan Carlos Ruíz San Millán, Emilio Rodrigo
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2741 (2023)
Kidney transplantation is the preferred therapeutic option for end-stage renal disease; however, the alloimmune response is still the leading cause of renal allograft failure. To better identify immunologic disparities in order to evaluate HLA compat
Externí odkaz:
https://doaj.org/article/a09e98adb08f44fdb61216fb1bcb910b
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The development of systems biology represents an immense breakthrough in our ability to perform translational research and deliver personalized and precision medicine. A multidisciplinary approach in combination with use of novel techniques allows fo
Externí odkaz:
https://doaj.org/article/c0eb47a52d13489b9823f1764eae03de
Autor:
André Renaldo, Adriel Roa-Bautista, Elena González-López, Marcos López-Hoyos, David San Segundo
Publikováno v:
Transplantology, Vol 2, Iss 3, Pp 336-347 (2021)
The development of de novo donor-specific antibodies is related to the poor matching of the human leukocyte antigen (HLA) between donor and recipient, which leads to dismal clinical outcomes and graft loss. However, new approaches that stratify the r
Externí odkaz:
https://doaj.org/article/7cfa5f3891d94345bee904032fa61b01
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