Zobrazeno 1 - 10
of 247
pro vyhledávání: '"epithelial plasticity"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/8c7749c29ef344cb95a81c910dd4f845
Autor:
Rui Wang, Zhaopeng Yan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Metastasis is a major cause of cancer-related deaths, underscoring the necessity to discern the rules and patterns of cancer cell spreading. Epithelial-mesenchymal plasticity contributes to cancer aggressiveness and metastasis. Despite
Externí odkaz:
https://doaj.org/article/9b10d87df05f4e22b76d09cbb9c3f58b
Autor:
Özgecan Kayalar, Hadi Rajabi, Nur Konyalilar, Deniz Mortazavi, Gizem Tuşe Aksoy, Jun Wang, Hasan Bayram
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Air pollution plays an important role in the mortality and morbidity of chronic airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Particulate matter (PM) is a significant fraction of air pollutants, and studies have de
Externí odkaz:
https://doaj.org/article/3942c112565041bda3a2efcb350ea928
Autor:
Kathryn E. Ware, Beatrice C. Thomas, Pelumi D. Olawuni, Maya U. Sheth, Nathan Hawkey, M. Yeshwanth, Brian C. Miller, Katherine J. Vietor, Mohit Kumar Jolly, So Young Kim, Andrew J. Armstrong, Jason A. Somarelli
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Despite substantial improvements in the treatment landscape of prostate cancer, the evolution of hormone therapy-resistant and metastatic prostate cancer remains a major cause of cancer-related death globally. The mainstay of treatment for advanced p
Externí odkaz:
https://doaj.org/article/1387a5257992495d9a15d49c7db46780
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Repetitive aeroallergen exposure is linked to sensitization and airway remodeling through incompletely understood mechanisms. In this study, we examine the dynamic mucosal response to cat dander extract (CDE), a ubiquitous aero-allergen link
Externí odkaz:
https://doaj.org/article/8da0664848fd432387988dcd6573f052
Autor:
Naser Jafari, Andrew Chen, Manohar Kolla, Isabella R. Pompa, Yuhan Qiu, Rebecca Yu, Pablo Llevenes, Christina S. Ennis, Joakin Mori, Kiana Mahdaviani, Meredith Halpin, Gretchen A. Gignac, Christopher M. Heaphy, Stefano Monti, Gerald V. Denis
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 6, Iss , Pp 100073- (2022)
Comorbid Type 2 diabetes (T2D), a metabolic complication of obesity, associates with worse cancer outcomes for prostate, breast, head and neck, colorectal and several other solid tumors. However, the molecular mechanisms remain poorly understood. Eme
Externí odkaz:
https://doaj.org/article/a56f2904908740e8aa0e2a0c91a20861
Autor:
Déborah Neyrinck-Leglantier, Julien Lesage, Silvia Blacher, Arnaud Bonnomet, Walter Hunziker, Agnès Noël, Valérian Dormoy, Béatrice Nawrocki-Raby, Christine Gilles, Myriam Polette
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Delocalization of zonula occludens-1 (ZO-1) from tight junctions plays a substantial role in epithelial cell plasticity observed during tumor progression. In vitro, we reported an impact of ZO-1 cyto-nuclear content in modulating the secretion of sev
Externí odkaz:
https://doaj.org/article/9d1943e2c9f4411984740c92b60c8388
Akademický článek
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Akademický článek
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Autor:
Zuzana Budkova, Anna Karen Sigurdardottir, Eirikur Briem, Jon Thor Bergthorsson, Snævar Sigurdsson, Magnus Karl Magnusson, Gunnhildur Asta Traustadottir, Thorarinn Gudjonsson, Bylgja Hilmarsdottir
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Epithelial-to-mesenchymal transition (EMT) and its reversed process mesenchymal-to-epithelial transition (MET) play a critical role in epithelial plasticity during development and cancer progression. Among important regulators of these cellular proce
Externí odkaz:
https://doaj.org/article/e07a06748c2249c59761666b7b9b3b2d