Zobrazeno 1 - 10
of 161
pro vyhledávání: '"episomal vectors"'
Akademický článek
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Autor:
Phatchanat Klaihmon, Sudjit Luanpitpong, Chanchao Lorthongpanich, Chuti Laowtammathron, Supaporn Waeteekul, Papussorn Terbto, Surapol Issaragrisil
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102472- (2021)
Natural killer (NK) cells were isolated from human umbilical cord blood from a healthy newborn and reprogrammed by episomal vectors carrying reprograming factors L-MYC, LIN28, OCT4, SOX2, KLF4, EBNA-1, and shRNA against p53 delivered using nucleofect
Externí odkaz:
https://doaj.org/article/6ab2f93043734c53875893df6ddf6658
Akademický článek
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Autor:
Xihe Tang, Shuyan Wang, Yunfei Bai, Jianyu Wu, Linlin Fu, Mo Li, Qunyuan Xu, Zhi-Qing David Xu, Y. Alex Zhang, Zhiguo Chen
Publikováno v:
Stem Cell Research, Vol 16, Iss 2, Pp 236-242 (2016)
Human neural stem cells (NSCs) hold great promise for research and therapy in neural diseases. Many studies have shown direct induction of NSCs from human fibroblasts, which require an invasive skin biopsy and a prolonged period of expansion in cell
Externí odkaz:
https://doaj.org/article/f5e32b95ab354fe9863c051274568616
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13633-13648 (2015)
Mesenchymal stem cells (MSCs) are considered a potential autologous therapy for tissue engineering. The available procedures for MSC retrieval from patients are invasive, and their limited in vitro proliferation restricts their use in the treatment o
Externí odkaz:
https://doaj.org/article/d7571a4e07534be8a733e5c4bc4d94cc
Autor:
Karl Friehs, Jan-Philipp Schwarzhans, Tobias Luttermann, Daniel Wibberg, Anika Winkler, Wolfgang Hübner, Thomas Huser, Jörn Kalinowski
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pichia pastoris is a non-conventional methylotrophic yeast that is widely used for recombinant protein production, typically by stably integrating the target gene into the genome as part of an expression cassette. However, the comparatively high clon
Externí odkaz:
https://doaj.org/article/77f9aedd91804ea28e11683b0d548ca5
Autor:
Victoria C. de Leeuw, Conny T. M. van Oostrom, Martijn E.T. Dollé, Sandra Imholz, Aldert H. Piersma, Ellen V.S. Hessel
Publikováno v:
Cellular Reprogramming
Human induced pluripotent stem cells (iPSCs) can capture the diversity in the general human population as well as provide deeper insight in cellular mechanisms. This makes them suitable to study both fundamental and applied research subjects, such as
Akademický článek
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Autor:
Mirko Pinotti, Simko Sama, Hardy Mitdank, Dario Balestra, Meike Tröger, Maria Francesca Testa, Mattia Ferrarese, Alexander Weng
Minicircle DNA is a promising tool in the field of gene therapy, whose products are increasingly gaining market access. Greater transfection efficiency and longer expression time as well as lower immunogenicity contrast with cost-intensive production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90323116615ddb20efb7f2655fe55148
https://hdl.handle.net/11392/2460114
https://hdl.handle.net/11392/2460114