Epigenetic modifications: Allusive clues of lncRNA functions in plants

Autor: Wenjing Yang, Quanzi Bai, Yan Li, Jianghua Chen, Changning Liu

Publikováno v: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1989-1994 (2023)

Long non-coding RNAs (lncRNAs) have been verified as flexible and important factors in various biological processes of multicellular eukaryotes, including plants. The respective intricate crosstalk among multiple epigenetic modifications has been exa

Externí odkaz: https://doaj.org/article/3e0a2770148643bf8c6d26f13ae96418

Clinical Epigenetics on the Baltic Coast

Autor: Ryszard Maleszka

Publikováno v: Epigenomes, Vol 6, Iss 3, p 19 (2022)

This report summarizes the proceedings of the inaugural Clinical Epigenetics Conference that was held in Szczecin, Poland, from 8 June 2022. With focus on epigenetic diseases whose causes, progression, and prognosis are associated with aberrant epige

Externí odkaz: https://doaj.org/article/43747e8ccca84735847b6cb87e74ae51

The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models

Autor: Joel Rozowsky, Jiahao Gao, Beatrice Borsari, Yucheng T. Yang, Timur Galeev, Gamze Gürsoy, Charles B. Epstein, Kun Xiong, Jinrui Xu, Tianxiao Li, Jason Liu, Keyang Yu, Ana Berthel, Zhanlin Chen, Fabio Navarro, Maxwell S. Sun, James Wright, Justin Chang, Christopher J.F. Cameron, Noam Shoresh, Elizabeth Gaskell, Jorg Drenkow, Jessika Adrian, Sergey Aganezov, François Aguet, Gabriela Balderrama-Gutierrez, Samridhi Banskota, Guillermo Barreto Corona, Sora Chee, Surya B. Chhetri, Gabriel Conte Cortez Martins, Cassidy Danyko, Carrie A. Davis, Daniel Farid, Nina P. Farrell, Idan Gabdank, Yoel Gofin, David U. Gorkin, Mengting Gu, Vivian Hecht, Benjamin C. Hitz, Robbyn Issner, Yunzhe Jiang, Melanie Kirsche, Xiangmeng Kong, Bonita R. Lam, Shantao Li, Bian Li, Xiqi Li, Khine Zin Lin, Ruibang Luo, Mark Mackiewicz, Ran Meng, Jill E. Moore, Jonathan Mudge, Nicholas Nelson, Chad Nusbaum, Ioann Popov, Henry E. Pratt, Yunjiang Qiu, Srividya Ramakrishnan, Joe Raymond, Leonidas Salichos, Alexandra Scavelli, Jacob M. Schreiber, Fritz J. Sedlazeck, Lei Hoon See, Rachel M. Sherman, Xu Shi, Minyi Shi, Cricket Alicia Sloan, J Seth Strattan, Zhen Tan, Forrest Y. Tanaka, Anna Vlasova, Jun Wang, Jonathan Werner, Brian Williams, Min Xu, Chengfei Yan, Lu Yu, Christopher Zaleski, Jing Zhang, Kristin Ardlie, J Michael Cherry, Eric M. Mendenhall, William S. Noble, Zhiping Weng, Morgan E. Levine, Alexander Dobin, Barbara Wold, Ali Mortazavi, Bing Ren, Jesse Gillis, Richard M. Myers, Michael P. Snyder, Jyoti Choudhary, Aleksandar Milosavljevic, Michael C. Schatz, Bradley E. Bernstein, Roderic Guigó, Thomas R. Gingeras, Mark Gerstein

Understanding how genetic variants impact molecular phenotypes is a key goal of functional genomics, currently hindered by reliance on a single haploid reference genome. Here, we present the EN-TEx resource of 1,635 open-access datasets from four don

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464939170ba93b49ee4e474d325702f1
http://hdl.handle.net/10230/56942

Epigenomics of Pancreatic Cancer: A Critical Role for Epigenome-Wide Studies

Autor: Rahul R. Singh, Katie M. Reindl, Rick J. Jansen

Publikováno v: Epigenomes, Vol 3, Iss 1, p 5 (2019)

Several challenges present themselves when discussing current approaches to the prevention or treatment of pancreatic cancer. Up to 45% of the risk of pancreatic cancer is attributed to unknown causes, making effective prevention programs difficult t

Externí odkaz: https://doaj.org/article/b7c9e822230f4e06973e0aab3f1a4d34

Integrating High-Throughput Approaches and in vitro Human Trophoblast Models to Decipher Mechanisms Underlying Early Human Placenta Development

Autor: Jonghwan Kim, Bum-Kyu Lee

Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)

The placenta is a temporary but pivotal organ for human pregnancy. It consists of multiple specialized trophoblast cell types originating from the trophectoderm of the blastocyst stage of the embryo. While impaired trophoblast differentiation results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec633216c53d15f7531af56c0f6161f
http://europepmc.org/articles/PMC8206641