Zobrazeno 1 - 10
of 129
pro vyhledávání: '"epigenome-wide association study (ewas)"'
Autor:
Jiafei Wu, Victoria Palasantzas, Sergio Andreu-Sánchez, Torsten Plösch, Sam Leonard, Shuang Li, Marc Jan Bonder, Harm-Jan Westra, Joyce van Meurs, Mohsen Ghanbari, Lude Franke, Alexandra Zhernakova, Jingyuan Fu, Joanne A. Hoogerland, Daria V. Zhernakova
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background The plasma metabolome reflects the physiological state of various biological processes and can serve as a proxy for disease risk. Plasma metabolite variation, influenced by genetic and epigenetic mechanisms, can also affect the ce
Externí odkaz:
https://doaj.org/article/9ba2686e25cc4689806e48f764522f07
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Cocaine use (CU) is associated with psychiatric and medical diseases. Little is known about the mechanisms of CU-related comorbidities. Findings from preclinical and clinical studies have suggested that CU is associated with aberr
Externí odkaz:
https://doaj.org/article/267ee5fed7384dd1a73438d967bdead0
Autor:
Rachael V. Phillips, Linqing Wei, Andres Cardenas, Alan E. Hubbard, Cliona M. McHale, Roel Vermeulen, Hu Wei, Martyn T. Smith, Luoping Zhang, Qing Lan, Nathaniel Rothman
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2259-2277 (2022)
Sufficient evidence supports a relationship between certain myeloid neoplasms and exposure to benzene or formaldehyde. DNA methylation could underlie benzene- and formaldehyde-induced health outcomes, but data in exposed human populations are limited
Externí odkaz:
https://doaj.org/article/4596ba729e8e48bfacde40d777ec3090
Akademický článek
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Akademický článek
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Autor:
Naisi Zhao, Mengyuan Ruan, Devin C. Koestler, Jiayun Lu, Carmen J. Marsit, Karl T. Kelsey, Elizabeth A. Platz, Dominique S. Michaud
Publikováno v:
Epigenetics, Vol 17, Iss 4, Pp 460-472 (2022)
Background: DNA methylation markers have been associated with lung cancer risk and may identify aetiologically relevant genomic regions, or alternatively, be markers of disease risk factors or biological processes associated with disease development.
Externí odkaz:
https://doaj.org/article/26a22d3ddeac421d887ddb2bc5d0527c
Publikováno v:
Epigenetics, Vol 15, Iss 4, Pp 431-438 (2020)
The majority of methylome-wide association studies (MWAS) have been performed using commercially available array-based technologies such as the Infinium Human Methylation 450K and the Infinium MethylationEPIC arrays (Illumina). While these arrays off
Externí odkaz:
https://doaj.org/article/12df4d0fbde14a6da808bbe4af64ac0b
Akademický článek
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Autor:
Siyu Wei, Junxian Tao, Jing Xu, Xingyu Chen, Zhaoyang Wang, Nan Zhang, Lijiao Zuo, Zhe Jia, Haiyan Chen, Hongmei Sun, Yubo Yan, Mingming Zhang, Hongchao Lv, Fanwu Kong, Lian Duan, Ye Ma, Mingzhi Liao, Liangde Xu, Rennan Feng, Guiyou Liu, The EWAS Project, Yongshuai Jiang
Publikováno v:
Advanced Science, Vol 8, Iss 20, Pp n/a-n/a (2021)
Abstract Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation variation in complex diseases for a decade, and epigenome as a research target has gradually become a hot topic of current studies. The DNA methylation mic
Externí odkaz:
https://doaj.org/article/f988d869b57349538ee952d48734d0e9
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Isocyanates are respiratory and skin sensitizers that are one of the main causes of occupational asthma globally. Genetic and epigenetic markers are associated with isocyanate-induced asthma and, before asthma develops, we have shown that genetic pol
Externí odkaz:
https://doaj.org/article/8bbac9cec40045d5935bc1d57b57adb0