Zobrazeno 1 - 10
of 54
pro vyhledávání: '"epigenome engineering"'
Autor:
Alex de Mendoza, Trung Viet Nguyen, Ethan Ford, Daniel Poppe, Sam Buckberry, Jahnvi Pflueger, Matthew R. Grimmer, Sabine Stolzenburg, Ozren Bogdanovic, Alicia Oshlack, Peggy J. Farnham, Pilar Blancafort, Ryan Lister
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Background Cytosine DNA methylation is widely described as a transcriptional repressive mark with the capacity to silence promoters. Epigenome engineering techniques enable direct testing of the effect of induced DNA methylation on endogenou
Externí odkaz:
https://doaj.org/article/b7e0ceb7c87f42b496fd72cdb8d5a2de
Autor:
Eric Alves, Shahama Taifour, Riccardo Dolcetti, Jonathan Chee, Anna K. Nowak, Silvana Gaudieri, Pilar Blancafort
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 592-606 (2021)
Precise clustered regularly interspaced short palindromic repeats (CRISPR)-mediated genetic and epigenetic manipulation of the immune response has become a promising immunotherapeutic approach toward combating tumorigenesis and tumor progression. CRI
Externí odkaz:
https://doaj.org/article/3cd97d3e8a124910bc080c62f88cdcb8
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8314 (2022)
N6-methyladenine (6mA) has been recognized as a key epigenetic alteration that affects a variety of biological activities. Precise prediction of 6mA modification sites is essential for understanding the logical consistency of biological activity. The
Externí odkaz:
https://doaj.org/article/3a66199ba82b4bd7990269b55f5c85e4
Autor:
Liszczak, Glen P., Brown, Zachary Z., Kim, Samuel H., Oslund, Rob C., David, Yael, Muir, Tom W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Jan . 114(4), 681-686.
Externí odkaz:
https://www.jstor.org/stable/26479040
Autor:
Annick Dubois, François Roudier
Publikováno v:
Epigenomes, Vol 5, Iss 3, p 17 (2021)
CRISPR-based epigenome editing uses dCas9 as a platform to recruit transcription or chromatin regulators at chosen loci. Despite recent and ongoing advances, the full potential of these approaches to studying chromatin functions in vivo remains chall
Externí odkaz:
https://doaj.org/article/7c2b0cab773d4e118b4ab28c6b0badb9
Autor:
Shahama Taifour, Pilar Blancafort, Jonathan Chee, Riccardo Dolcetti, Anna K. Nowak, Silvana Gaudieri, Eric Alves
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 592-606 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Precise clustered regularly interspaced short palindromic repeats (CRISPR)-mediated genetic and epigenetic manipulation of the immune response has become a promising immunotherapeutic approach toward combating tumorigenesis and tumor progression. CRI
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1691, p 1691 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1691
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1691
Histone post-translational modifications are small chemical changes to the histone protein structure that have cascading effects on diverse cellular functions. Detecting histone modifications and characterizing their binding partners are critical ste
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
François Roudier, Annick Dubois
Publikováno v:
Epigenomes
Epigenomes, MDPI, 2021, 5 (3), pp.17. ⟨10.3390/epigenomes5030017⟩
Epigenomes, Vol 5, Iss 17, p 17 (2021)
Epigenomes, 2021, 5 (3), pp.17. ⟨10.3390/epigenomes5030017⟩
Epigenomes, MDPI, 2021, 5 (3), pp.17. ⟨10.3390/epigenomes5030017⟩
Epigenomes, Vol 5, Iss 17, p 17 (2021)
Epigenomes, 2021, 5 (3), pp.17. ⟨10.3390/epigenomes5030017⟩
International audience; CRISPR-based epigenome editing uses dCas9 as a platform to recruit transcription or chromatin regulators at chosen loci. Despite recent and ongoing advances, the full potential of these approaches to studying chromatin functio