Zobrazeno 1 - 10
of 444
pro vyhledávání: '"epigenetic regulators"'
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Parental epigenetic asymmetries, which contribute to the monoallelic expression of genes known as imprints, play a critical role in seed development in flowering plants. Primarily, differential DNA methylation patterns and histone modifications on pa
Externí odkaz:
https://doaj.org/article/c82d5f40a17f41939438b266d17b029d
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Targeted therapies, including small molecule inhibitors directed against aberrant kinase signaling and chromatin regulators, are emerging treatment options for high-grade gliomas (HGG). However, when translating these inhibitors into the cli
Externí odkaz:
https://doaj.org/article/0fd10c91f86f41818ccab433ecd08512
Autor:
Yumei Wang, Haiyan Wang, Wei Shao, Yuhui Chen, Yu Gui, Chao Hu, Xiaohong Yi, Lijun Huang, Shasha Li, Dong Wang
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 1, Pp 83-103 (2024)
Objective: Epigenetic abnormalities have a critical role in breast cancer by regulating gene expression; however, the intricate interrelationships and key roles of approximately 400 epigenetic regulators in breast cancer remain elusive. It is importa
Externí odkaz:
https://doaj.org/article/b19f4139df534722b75faf9d1daabcae
Autor:
Maria Rita Braghini, Cristiano De Stefanis, Francesca Tiano, Aurora Castellano, Nicolo’ Cicolani, Marco Pezzullo, Valeria Tocco, Marco Spada, Rita Alaggio, Anna Alisi, Paola Francalanci
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundHepatoblastoma (HB) is the most common pediatric hepatic malignancy. Despite the progress in HB treatment, investigating HB pathomechanisms to optimize stratification and therapies remains a focal point to improve the outcome for high-risk
Externí odkaz:
https://doaj.org/article/8bd7b6029ac04845acc9a9b1c3c3f685
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Naser Jafari, Andrew Chen, Manohar Kolla, Isabella R. Pompa, Yuhan Qiu, Rebecca Yu, Pablo Llevenes, Christina S. Ennis, Joakin Mori, Kiana Mahdaviani, Meredith Halpin, Gretchen A. Gignac, Christopher M. Heaphy, Stefano Monti, Gerald V. Denis
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 6, Iss , Pp 100073- (2022)
Comorbid Type 2 diabetes (T2D), a metabolic complication of obesity, associates with worse cancer outcomes for prostate, breast, head and neck, colorectal and several other solid tumors. However, the molecular mechanisms remain poorly understood. Eme
Externí odkaz:
https://doaj.org/article/a56f2904908740e8aa0e2a0c91a20861
Autor:
Ralf Müller-Xing, Qian Xing
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Pluripotent stem-cells are slowly dividing cells giving rise to daughter cells that can either differentiate to new tissues and organs, or remain stem-cells. In plants, stem-cells are located in specific niches of the shoot and root apical meristems
Externí odkaz:
https://doaj.org/article/153c1ecb57944533996140f99b850493
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Heliyon, Vol 8, Iss 7, Pp e09957- (2022)
Cancer development is related to a variety of signaling pathways which mediate various cellular processes including growth, survival, division and competition of cells, as well as cell-cell interaction. The insulin signaling pathway interacts with di
Externí odkaz:
https://doaj.org/article/230ce0765b8243ab8816911ec6c2dfe2
Autor:
Young-In Chi, Timothy J. Stodola, Thiago M. De Assuncao, Elise N. Levrence, Swarnendu Tripathi, Nikita R. Dsouza, Angela J. Mathison, Donald G. Basel, Brian F. Volkman, Brian C. Smith, Gwen Lomberk, Michael T. Zimmermann, Raul Urrutia
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-15 (2021)
Abstract Background Kabuki syndrome is a genetic disorder that affects several body systems and presents with variations in symptoms and severity. The syndrome is named for a common phenotype of faces resembling stage makeup used in a Japanese tradit
Externí odkaz:
https://doaj.org/article/34e18bd080514777804471ce11d0cb8c