Zobrazeno 1 - 10
of 2 142
pro vyhledávání: '"epigenetic mechanisms"'
Autor:
Rosana Carvalho Silva, Paolo Martini, Christa Hohoff, Stefania Mattevi, Marco Bortolomasi, Maria Abate, Valentina Menesello, Massimo Gennarelli, Bernhard T. Baune, Alessandra Minelli
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Electroconvulsive therapy (ECT) benefits patients with treatment-resistant depression (TRD), but the underlying biological processes are unclear. We conducted an epigenome-wide association study in 32 TRD patients undergoing ECT t
Externí odkaz:
https://doaj.org/article/031dcce795c94b22a5850eeb4717c714
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/292a0bd00bdd435aad3560942dea948f
Autor:
Guang‐Liang Chen, Kai Xue, Qunling Zhang, Zu‐guang Xia, Jia Jin, Ran Li, Yizhen Liu, Fangfang Lv, Xiaonan Hong, Xiaoqiu Li, Junning Cao
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Background In relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL), a negative prognosis is frequently linked to heightened epigenetic heterogeneity. Chidamide, a selective histone deacetylase inhibitor, shows promise as a targe
Externí odkaz:
https://doaj.org/article/2ad1fa44c0184b318107224eea500a7a
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Histone deacetylases (HDACs) are critical regulators of inflammatory gene expression, and the efficacy of pan-HDAC inhibitors has been implicated in various disease conditions. However, it remains largely unclear how HDACs precisely regulate inflamma
Externí odkaz:
https://doaj.org/article/d81fe5e1ec4249e288db44d34bd9d1fc
Autor:
Justyna Mierziak, Wioleta Wojtasik
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-23 (2024)
Abstract In the natural environment, plants face constant exposure to biotic stress caused by fungal attacks. The plant’s response to various biotic stresses relies heavily on its ability to rapidly adjust the transcriptome. External signals are tr
Externí odkaz:
https://doaj.org/article/d0633eb5000f48f08137d838d0e43833
Autor:
Thu N. A. Doan, James M. Cowley, Aaron L. Phillips, Jessica F. Briffa, Shalem Y. Leemaqz, Rachel A. Burton, Tania Romano, Mary E. Wlodek, Tina Bianco-Miotto
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTAltered epigenetic mechanisms have been previously reported in growth restricted offspring whose mothers experienced environmental insults during pregnancy in both human and rodent studies. We previously reported changes in the expression of
Externí odkaz:
https://doaj.org/article/087c2f47fb0c465788e81285c8540942
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/98734ef427844c3e96ac5e6bae0b3b7a
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Cervical carcinoma is the most prevalent gynecology malignant tumor and ranks as the fourth most common cancer worldwide, thus posing a significant threat to the lives and health of women. Advanced and early-stage cervical carcinoma patients with hig
Externí odkaz:
https://doaj.org/article/1f8bb2dc940c40b89a524b59653b11d2
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26991- (2024)
Nonalcoholic fatty liver disease (NAFLD) is a stress-induced liver injury related to heredity, environmental exposure and the gut microbiome metabolism. Short-chain fatty acids (SCFAs), the metabolites of gut microbiota (GM), participate in the regul
Externí odkaz:
https://doaj.org/article/c40009559b7540e38b875c18ba22594d
Autor:
Dillon E. King, Pooja D. Lalwani, Gilberto Padilla Mercado, Emma L. Dolan, Johnna M. Frierson, Joel N. Meyer, Susan K. Murphy
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The field of environmental epigenetics is uniquely suited to investigate biologic mechanisms that have the potential to link stressors to health disparities. However, it is common practice in basic epigenetic research to treat race as a covariable in
Externí odkaz:
https://doaj.org/article/5a47af73cec64f7eafd49881cdc0f7be