Zobrazeno 1 - 10
of 1 665
pro vyhledávání: '"epigenetic clock"'
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Gestational age (GEAA) estimated by newborn DNA methylation (GAmAge) is associated with maternal prenatal exposures and immediate birth outcomes. However, the association of GAmAge with long-term overweight or obesity (OWO) trajec
Externí odkaz:
https://doaj.org/article/5d2a0b61fb5e41d2a3b4091017ef51c1
Autor:
Calzari Luciano, Dragani Davide Fernando, Zanotti Lucia, Inglese Elvira, Danesi Romano, Cavagnola Rebecca, Brusati Alberto, Ranucci Francesco, Di Blasio Anna Maria, Persani Luca, Campi Irene, De Martino Sara, Farsetti Antonella, Barbi Veronica, Gottardi Zamperla Michela, Baldrighi Giulia Nicole, Gaetano Carlo, Parati Gianfranco, Gentilini Davide
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background The epigenetic status of patients 6-month post-COVID-19 infection remains largely unexplored. The existence of long-COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), suggests potential long-term changes. Long-COVID inc
Externí odkaz:
https://doaj.org/article/5aa899ca5e134dd484d3203ed10f78d0
Autor:
Anat Yaskolka Meir, Maria Jimena Gutierrez, Xiumei Hong, Guoying Wang, Xiaobin Wang, Liming Liang
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Gestational DNA methylation age (GAmAge) has been developed and validated in European ancestry samples. Its applicability to other ethnicities and associations with fetal stress and newborn phenotypes such as inflammation markers
Externí odkaz:
https://doaj.org/article/652a974aa1b04e04aa4b568b7a0f55d9
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Age-related eye diseases (AREDs) have become increasingly prevalent with the aging population, serving as the leading causes of visual impairment worldwide. Epigenetic clocks are generated based on DNA methylation (DNAm) levels an
Externí odkaz:
https://doaj.org/article/27ec24edb35a4dc79d0f80c98739ae4e
Autor:
Lindsay L. Sailer, Amin Haghani, Joseph A. Zoller, Caesar Z. Li, Alexander G. Ophir, Steve Horvath
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The quality of romantic relationships can predict health consequences related to aging. DNA methylation-based biomarkers of aging accurately estimate chronological age. We developed several highly accurate epigenetic aging clocks, based on h
Externí odkaz:
https://doaj.org/article/dd1ce82f5355449180298d31767d1482
Autor:
Guan-yi Chen, Chao Liu, Yu Xia, Ping-xiao Wang, Zi-yue Zhao, Ao-yu Li, Chu-qiao Zhou, Cheng Xiang, Jia-lin Zhang, Yi Zeng, Peng Gu, Hui Li
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Introduction Walking stands as the most prevalent physical activity in the daily lives of individuals and is closely associated with physical functioning and the aging process. Nonetheless, the precise cause-and-effect connection between wal
Externí odkaz:
https://doaj.org/article/a29fc1a9a5ca4e849607a24a0e9b900e
Autor:
Ke Miao, Shunkai Liu, Weihua Cao, Jun Lv, Canqing Yu, Tao Huang, Dianjianyi Sun, Chunxiao Liao, Yuanjie Pang, Runhua Hu, Zengchang Pang, Min Yu, Hua Wang, Xianping Wu, Yu Liu, Wenjing Gao, Liming Li
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Epigenetic clocks were known as promising biomarkers of aging, including original clocks trained by individual CpG sites and principal component (PC) clocks trained by PCs of CpG sites. The effects of genetic and environmental fac
Externí odkaz:
https://doaj.org/article/c44adc774d8b4a2fa2bfd6f3a6665d46
Autor:
Celia Lujan, Eleanor Jane Tyler, Simone Ecker, Amy Philomena Webster, Eleanor Rachel Stead, Victoria Eugenia Martinez-Miguel, Deborah Milligan, James Charles Garbe, Martha Ruskin Stampfer, Stephan Beck, Robert Lowe, Cleo Lucinda Bishop, Ivana Bjedov
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Restraining or slowing ageing hallmarks at the cellular level have been proposed as a route to increased organismal lifespan and healthspan. Consequently, there is great interest in anti-ageing drug discovery. However, this curren
Externí odkaz:
https://doaj.org/article/8bc7311ebeed472eb18cda1fe5ab77ae
Autor:
Shibabrata Pattanayak
Publikováno v:
Exploratory Animal and Medical Research, Vol 14, Iss 1, Pp 1-5 (2024)
The biological age of an individual depends mainly on the genetic status and different epigenetic influences experienced by the individual and it has a direct relationship with aging and suffering from different diseases. It can be understood from th
Externí odkaz:
https://doaj.org/article/b5be75aab368423c9dcf3704936faac9
Autor:
Gauri G. Shastri, Gustavo Sudre, Kwangmi Ahn, Benjamin Jung, Bhaskar Kolachana, Pavan K. Auluck, Laura Elnitski, Philip Shaw
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Mathematical algorithms known as “epigenetic clocks” use methylation values at a set of CpG sites to estimate the biological age of an individual in a tissue-specific manner. These clocks have demonstrated both acceleration and delays in epigenet
Externí odkaz:
https://doaj.org/article/cb44e07a18434e18ba05a229218d9b77