Zobrazeno 1 - 10
of 1 161
pro vyhledávání: '"epigenetic age"'
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Epigenetic age accelerations (EAAs) are a promising new avenue of research, yet their investigation in subacute thyroiditis (SAT) remains scarce. Our study endeavors to fill this void by exploring the potential causal association
Externí odkaz:
https://doaj.org/article/a667ece472cf4c67b504de44eb0b4048
Autor:
Gabin Drouard, Zhiyang Wang, Aino Heikkinen, Maria Foraster, Jordi Julvez, Katja M. Kanninen, Irene van Kamp, Matti Pirinen, Miina Ollikainen, Jaakko Kaprio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Whether differences in lifestyle between co-twins are reflected in differences in their internal or external exposome profiles remains largely underexplored. We therefore investigated whether within-pair differences in lifestyle were associa
Externí odkaz:
https://doaj.org/article/0a76e6177f3c42b88f40bdd76d1f58ad
Autor:
Manli Sun, Huan Yang, Yang Hu, Jiaqi Fan, Mingjing Duan, Jingqi Ruan, Shichang Li, Yang Xu, Yue Han
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-8 (2024)
Abstract Background Human aging and white blood cell (WBC) count are complex traits influenced by multiple genetic factors. Predictors of chronological age have been developed using epigenetic clocks. However, the bidirectional causal effects between
Externí odkaz:
https://doaj.org/article/17f1cc0acbc74c2a8e2b8b3654a6e545
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Telomere shortening and epigenetic modifications are key factors in aging and hematologic diseases. This study investigates the relationship of telomere length and epigenetic age acceleration (EAA) with hematologic cancers, blood
Externí odkaz:
https://doaj.org/article/9054af286b1b4d509aa333f2703939aa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Hypertension is a disease associated with epigenetic aging. However, the pathogenic mechanism underlying this relationship remains unclear. We aimed to characterize the shared genetic architecture of hypertension and epigenetic aging, and id
Externí odkaz:
https://doaj.org/article/4c486fdbeb674321806a1fd1b315a4ad
Autor:
Guan-yi Chen, Chao Liu, Yu Xia, Ping-xiao Wang, Zi-yue Zhao, Ao-yu Li, Chu-qiao Zhou, Cheng Xiang, Jia-lin Zhang, Yi Zeng, Peng Gu, Hui Li
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Introduction Walking stands as the most prevalent physical activity in the daily lives of individuals and is closely associated with physical functioning and the aging process. Nonetheless, the precise cause-and-effect connection between wal
Externí odkaz:
https://doaj.org/article/a29fc1a9a5ca4e849607a24a0e9b900e
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Healthy sleep is vital for maintaining optimal mental and physical health. Accumulating evidence suggests that sleep loss and disturbances play a significant role in the biological aging process, early onset of disease, and reduce
Externí odkaz:
https://doaj.org/article/c73f7ff8406a4bb69d041be94b0e006f
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The epigenetic-age acceleration (EAA) represents the difference between chronological age and epigenetic age, reflecting accelerated biological aging. Observational studies suggested that oral disorders may impact DNA methylation
Externí odkaz:
https://doaj.org/article/09462bf15c1b4ab3948c77cec51359fd
Autor:
Gauri G. Shastri, Gustavo Sudre, Kwangmi Ahn, Benjamin Jung, Bhaskar Kolachana, Pavan K. Auluck, Laura Elnitski, Philip Shaw
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Mathematical algorithms known as “epigenetic clocks” use methylation values at a set of CpG sites to estimate the biological age of an individual in a tissue-specific manner. These clocks have demonstrated both acceleration and delays in epigenet
Externí odkaz:
https://doaj.org/article/cb44e07a18434e18ba05a229218d9b77
Autor:
Dong-Wook Lee, Youn-Hee Lim, Yoon-Jung Choi, Soontae Kim, Choong Ho Shin, Young Ah Lee, Bung-Nyun Kim, Johanna Inhyang Kim, Yun-Chul Hong
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116823- (2024)
Background: This study investigated the association of prenatal and early childhood exposure to air pollution with epigenetic age acceleration (EAA) at six years of age using the Environment and Development of Children Cohort (EDC Cohort) Materials &
Externí odkaz:
https://doaj.org/article/7363dcc68274453ba5207e21b9b7aca6