Zobrazeno 1 - 10
of 228
pro vyhledávání: '"epiallele"'
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/324c17e34dd142a1ae47d8d182028f56
Autor:
Jennifer Derrien, Catherine Guérin-Charbonnel, Victor Gaborit, Loïc Campion, Magali Devic, Elise Douillard, Nathalie Roi, Hervé Avet-Loiseau, Olivier Decaux, Thierry Facon, Jan-Philipp Mallm, Roland Eils, Nikhil C. Munshi, Philippe Moreau, Carl Herrmann, Florence Magrangeas, Stéphane Minvielle
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-21 (2021)
Abstract Background Cancer evolution depends on epigenetic and genetic diversity. Historically, in multiple myeloma (MM), subclonal diversity and tumor evolution have been investigated mostly from a genetic perspective. Methods Here, we performed an
Externí odkaz:
https://doaj.org/article/4a911b1129d149468316660d33d6e2e4
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
If food and feed production are to keep up with world demand in the face of climate change, continued progress in understanding and utilizing both genetic and epigenetic sources of crop variation is necessary. Progress in plant breeding has tradition
Externí odkaz:
https://doaj.org/article/1222a364b300489da4e5b2ac4652e3f5
Autor:
Jessica L. Elmer, Amir D. Hay, Noah J. Kessler, Tessa M. Bertozzi, Eve A. C. Ainscough, Anne C. Ferguson-Smith
Publikováno v:
Mobile DNA, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Transposable elements (TEs) are enriched in cytosine methylation, preventing their mobility within the genome. We previously identified a genome-wide repertoire of candidate intracisternal A particle (IAP) TEs in mice that exhibit
Externí odkaz:
https://doaj.org/article/adf7dc0066924ceb83c4919b87a03967
Publikováno v:
Journal of Central European Agriculture, Vol 21, Iss 1, Pp 56-61 (2020)
Current farming technology and advanced techniques of plant breeding are tending to enable high yields and cropping intensity, trying to alleviate the limitations of available arable land. However, rise in global population and climate changes could
Externí odkaz:
https://doaj.org/article/276026476227447a9a25d487b8874da1
Autor:
Matt J Silver, Ayden Saffari, Noah J Kessler, Gririraj R Chandak, Caroline HD Fall, Prachand Issarapu, Akshay Dedaniya, Modupeh Betts, Sophie E Moore, Michael N Routledge, Zdenko Herceg, Cyrille Cuenin, Maria Derakhshan, Philip T James, David Monk, Andrew M Prentice
Publikováno v:
eLife, Vol 11 (2022)
In humans, DNA methylation marks inherited from gametes are largely erased following fertilisation, prior to construction of the embryonic methylome. Exploiting a natural experiment of seasonal variation including changes in diet and nutritional stat
Externí odkaz:
https://doaj.org/article/3e0df17bd8c3409aa09b5b63f8a77876
Autor:
Semira Gonseth, Gary M. Shaw, Ritu Roy, Mark R. Segal, Kripa Asrani, Jasper Rine, Joseph Wiemels, Nicholas J. Marini
Publikováno v:
Epigenetics, Vol 14, Iss 2, Pp 198-213 (2019)
Cleft lip with or without cleft palate (CL/P) is a common human birth defect whose etiologies remain largely unknown. Several studies have demonstrated that periconceptional supplementation of folic acid can reduce risk of CL/P in offspring. In this
Externí odkaz:
https://doaj.org/article/a44c6ec8b0b940e9b45c59b522f17f40
Autor:
Tessa M Bertozzi, Nozomi Takahashi, Geula Hanin, Anastasiya Kazachenka, Anne C Ferguson-Smith
Publikováno v:
eLife, Vol 10 (2021)
Intracisternal A-particles (IAPs) are endogenous retroviruses (ERVs) responsible for most insertional mutations in the mouse. Full-length IAPs harbour genes flanked by long terminal repeats (LTRs). Here, we identify a solo LTR IAP variant (Iap5-1solo
Externí odkaz:
https://doaj.org/article/4caac09a8a9045a3843ff3ffbcc0dcd7
Autor:
Parvathy Krishnan, Lukas Meile, Clémence Plissonneau, Xin Ma, Fanny E. Hartmann, Daniel Croll, Bruce A. McDonald, Andrea Sánchez-Vallet
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background Fungal plant pathogens pose major threats to crop yield and sustainable food production if they are highly adapted to their host and the local environment. Variation in gene expression contributes to phenotypic diversity within fu
Externí odkaz:
https://doaj.org/article/fb46082c436f40379d53b2a1e73850c0
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-16 (2017)
Abstract Background Differences in DNA methylation can arise as epialleles, which are loci that differ in chromatin state and are inherited over generations. Epialleles offer an additional source of variation that can affect phenotypic diversity beyo
Externí odkaz:
https://doaj.org/article/99fefa956d874324a626bb5c8bb9addb