Zobrazeno 1 - 10
of 130
pro vyhledávání: '"engineered extracellular vesicles"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 12793-12815 (2024)
Yuhan Li,1,* Yulong Wang,1,* Hongrui Zhao,2 Qi Pan,3 Guihao Chen3 1Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Intensive Care Medicine Department, Yuhuangding Hospital, Yantai,
Externí odkaz:
https://doaj.org/article/418073e668184b84aec434d8f119e294
Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Autor:
Shuang Zhao, Yunfeng Di, Huilan Fan, Chengyan Xu, Haijing Li, Yong Wang, Wei Wang, Chun Li, Jingyu Wang
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-23 (2024)
Abstract Extracellular vesicles (EVs) are cell-derived vesicles with a phospholipid bilayer measuring 50–150 nm in diameter with demonstrated therapeutic potentials. Limitations such as the natural biodistribution (mainly concentrated in the liver
Externí odkaz:
https://doaj.org/article/23e394491b984140a858b93cc1c71923
Publikováno v:
BioMedical Engineering OnLine, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Background Extracellular vesicles (EVs) have emerged as an exciting tool for targeted delivery of therapeutics for a wide range of diseases. As nano-scale membrane-bound particles derived from living cells, EVs possess inherent capabilities
Externí odkaz:
https://doaj.org/article/6c79735bf1b549dba28636b9ab6e274a
Autor:
Jiayi Zhao, Huang Huang
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 9430-9448 (2024)
Heart failure (HF), a syndrome of persistent development of cardiac insufficiency due to various heart diseases, is a serious and lethal disease for which specific curative therapies are lacking and poses a severe burden on all aspects of global publ
Externí odkaz:
https://doaj.org/article/db9e8e3720e147cba4b85d154af5662d
Autor:
Chun-Chieh Huang, Miya Kang, Koushik Debnath, Kasey Leung, Vidhath Raghavan, Yu Lu, Lyndon F. Cooper, Praveen Gajendrareddy, Sriram Ravindran
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
IntroductionMesenchymal stem cell-derived extracellular vesicles (MSC EVs) hold significant promise for regenerative medicine. Lyophilization of EVs significantly enhances their translational potential. While, lyophilized EVs have been studied from a
Externí odkaz:
https://doaj.org/article/50e4dbedf6d640cf8ed01c2ab3094ba9
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Cancer, a prevalent and complex disease, presents a significant challenge to the medical community. It is characterized by irregular cell differentiation, excessive proliferation, uncontrolled growth, invasion of nearby tissues, and spread t
Externí odkaz:
https://doaj.org/article/d645e0795cb54dd28cb406ba0e1301ab
Akademický článek
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Autor:
Hanming Yao, Chengzhi Huang, Jinmao Zou, Weiling Liang, Yue Zhao, Kege Yang, Ziyi Zhong, Shurui Zhou, Jiajia Li, Yaqing Li, Lishu Xu, Kaihong Huang, Guoda Lian
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterised by immune evasion that contribute to poor prognosis. Cancer‐associated fibroblasts (CAFs) play a pivotal role in orchestrating the PDAC tumour microenvironment. We investigated the r
Externí odkaz:
https://doaj.org/article/e1bf69a7b1594b22a954c40d4f801f09
Autor:
Zhengyan Gu, Mingxue Sun, Jihao Liu, Qi Huang, Yunqin Wang, Jun Liao, Tingbin Shu, Min Tao, Guanchao Mao, Zhipeng Pei, Wenqi Meng, Xinkang Zhang, Youheng Wei, Shanshan Zhang, Songling Li, Kai Xiao, Ying Lu, Qingqiang Xu
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Acute lung injury (ALI) is a severe respiratory disease with a high mortality rate. The integrity of the pulmonary endothelial barrier influences the development and prognosis of ALI. Therefore, it has become an important target for ALI trea
Externí odkaz:
https://doaj.org/article/3bc9a4aec0cb45a2bc06ce949beaf530
Autor:
Zeng Wang, Zhizhen Qin, Jiadie Wang, Xinqi Xu, Mengxin Zhang, Yuyue Liang, Yukun Huang, Zengyang Yu, Yu Gong, Luxian Zhou, Yiran Qiu, Minglu Ma, Dan Li, Bin Li
Publikováno v:
Journal of Dermatological Treatment, Vol 34, Iss 1 (2023)
Introduction Herein, we developed an engineered extracellular vehicle (EV)-based method for ameliorating inflammatory responses in psoriasis. Methods EVs, derived from annexin A1 (ANXA1) overexpressing T cells, were co-extruded with M2 macrophage mem
Externí odkaz:
https://doaj.org/article/84e6e3f901ad4f88970a91899a1ce487