Zobrazeno 1 - 10
of 316
pro vyhledávání: '"endothelial cells (ECs)"'
Autor:
Alonso Tapia, Xuejing Liu, Naseeb Kaur Malhi, Dongqiang Yuan, Muxi Chen, Kevin W. Southerland, Yingjun Luo, Zhen Bouman Chen
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-34 (2024)
Abstract Diabetes mellitus (DM) is a metabolic disease that heightens the risks of many vascular complications, including peripheral arterial disease (PAD). Various types of cells, including but not limited to endothelial cells (ECs), vascular smooth
Externí odkaz:
https://doaj.org/article/fce792d7e3bc469782e492d04c28591f
Autor:
Wei Fan, Shuhao Zeng, Xiaotang Wang, Guoqing Wang, Dan Liao, Ruonan Li, Siyuan He, Wanqian Li, Jiaxing Huang, Xingran Li, Jiangyi Liu, Na Li, Shengping Hou
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Vascular endothelial growth factor (VEGF) is one of the most powerful proangiogenic factors and plays an important role in multiple diseases. Increased glycolytic rates and lactate accumulation are associated with pathological ang
Externí odkaz:
https://doaj.org/article/a334450576d84a65bb772018dbd71335
Autor:
Yasuteru Inoue, Yingxue Ren, Shuwen Zhang, Michael Bamkole, Naeyma N. Islam, Manikandan Selvaraj, Wenyan Lu, Thomas R. Caulfield, Yonghe Li, Takahisa Kanekiyo
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The maturation of brain microvascular endothelial cells leads to the formation of a tightly sealed monolayer, known as the blood–brain barrier (BBB). The BBB damage is associated with the pathogenesis of age-related neurodegenerative diseases inclu
Externí odkaz:
https://doaj.org/article/044332bc5f914607b440f788e2c9c05e
Publikováno v:
Biosensors, Vol 14, Iss 10, p 489 (2024)
For rapid and convenient detection of living endothelial cells (ECs) specifically without immunostaining, we developed a biosensor based on turn-on fluorescent protein, named LV-EcpG. It includes a high-affinity peptide E12P obtained through phage di
Externí odkaz:
https://doaj.org/article/d23e10fa3bc8404ea5a58758a1133696
Autor:
Junyang Huang, Kun Zhang, Ruolin Du, Wanling Liu, Haijun Zhang, Tian Tian, Yazhou Wang, Guixue Wang, Tieying Yin
Publikováno v:
Genes and Diseases, Vol 10, Iss 5, Pp 1956-1968 (2023)
In recent years, cardiovascular health problems are becoming more and more serious. At the same time, mechanical stimulation closely relates to cardiovascular health. In this context, Piezo1, which is very sensitive to mechanical stimulation, has att
Externí odkaz:
https://doaj.org/article/7f524e0a8d454db7ab7ef943a2460d66
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1795 (2024)
Brain arteriovenous malformations (bAVMs) substantially increase the risk for intracerebral hemorrhage (ICH), which is associated with significant morbidity and mortality. However, the treatment options for bAVMs are severely limited, primarily relyi
Externí odkaz:
https://doaj.org/article/9065bdae760a4ec793d350c0fa038d6c
Publikováno v:
Cells, Vol 13, Iss 16, p 1345 (2024)
Currently, there is a growing focus on aging and age-related diseases. The processes of aging are based on cell senescence, which results in changes in intercellular communications and pathological alterations in tissues. In the present study, we inv
Externí odkaz:
https://doaj.org/article/46a6d083c3094af3b9a656860da6cbd5
Autor:
Oscar Fraile-Martinez, Diego De Leon-Oliva, Diego Liviu Boaru, Patricia De Castro-Martinez, Cielo Garcia-Montero, Silvestra Barrena-Blázquez, Joaquin García-García, Natalio García-Honduvilla, Melchor Alvarez-Mon, Laura Lopez-Gonzalez, Raul Diaz-Pedrero, Luis G. Guijarro, Miguel A. Ortega
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Vascular diseases pose major health challenges, and understanding their underlying molecular mechanisms is essential to advance therapeutic interventions. Cellular senescence, a hallmark of aging, is a cellular state characterized by cell-cycle arres
Externí odkaz:
https://doaj.org/article/5bb5ac267c834429a34fb0d797622c46
Autor:
Muhammad Ahmer Jamil, Rawya Al-Rifai, Nicole Nuesgen, Janine Altmüller, Johannes Oldenburg, Osman El-Maarri
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Coagulation Factor VIII (FVIII) plays a pivotal role in the coagulation cascade, and deficiencies in its levels, as seen in Hemophilia A, can lead to significant health implications. Liver sinusoidal endothelial cells (LSECs) are the ma
Externí odkaz:
https://doaj.org/article/7213597cbc6f4b008dd82651c72b8c20
Autor:
Dario Troise, Barbara Infante, Silvia Mercuri, Claudia Piccoli, Bengt Lindholm, Giovanni Stallone
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 537 (2024)
The paracrine signaling pathways for the crosstalk between pericytes and endothelial cells are essential for the coordination of cell responses to challenges such as hypoxia in both healthy individuals and pathological conditions. Ischemia–reperfus
Externí odkaz:
https://doaj.org/article/27de547acb114938b817c41d817690fb