Zobrazeno 1 - 10
of 2 503
pro vyhledávání: '"endothelial barrier"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Acute lung injury (ALI) is a severe clinical respiratory condition characterized by high rates of mortality and morbidity, for which effective treatments are currently lacking. In this study, lipopolysaccharide (LPS) was used to induce ALI m
Externí odkaz:
https://doaj.org/article/a18d580686c548f3a4f9382ef2c85bac
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract The success of lung transplantation is limited by the high rate of primary graft dysfunction due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory response, lung dysfunction, endothelial barrier disrupt
Externí odkaz:
https://doaj.org/article/fbd37829100a471980e44bfbb336bf22
Autor:
Twamley SG, Gimber N, Sánchez-Ibarra HE, Christaller T, Isakzai V, Kratz H, Mitra R, Kampen L, Stach A, Heilmann H, Söhl-Kielczynski B, Ebong EE, Schmoranzer J, Münster-Wandowski A, Ludwig A
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 3123-3142 (2024)
Shailey Gale Twamley,1– 3 Niclas Gimber,4 Héctor Eduardo Sánchez-Ibarra,1,2 Tobias Christaller,1,2 Victoria Isakzai,1,2 Harald Kratz,5 Ronodeep Mitra,6 Lena Kampen,1– 3 Anke Stach,1,2 Heike Heilmann,7 Berit Söhl-Kielczynski,8 Eno Essien Ebong,
Externí odkaz:
https://doaj.org/article/5765af8c32d94bb68025b1efdb39fa53
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The destruction of the microvascular structure and function can seriously affect the survival and prognosis of patients with acute myocardial infarction (AMI). Nuciferine has a potentially beneficial effect in the treatment of cardiovascular
Externí odkaz:
https://doaj.org/article/3b43503f42344fef9569a871f7dede78
Autor:
Evgenia Gerasimovskaya, Rahul S. Patil, Adrian Davies, McKenzie E. Maloney, Liselle Simon, Basmah Mohamed, Mary Cherian-Shaw, Alexander D. Verin
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The purinergic signaling system is an evolutionarily conserved and critical regulatory circuit that maintains homeostatic balance across various organ systems and cell types by providing compensatory responses to diverse pathologies. Despite cardiova
Externí odkaz:
https://doaj.org/article/42e1427200574c2595c2de227c691497
Autor:
Michael P. Bokoch, Fengyun Xu, Krishna Govindaraju, Elliot Lloyd, Kyle Tsutsui, Rishi P. Kothari, Dieter Adelmann, Jérémie Joffre, Judith Hellman
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionPatients with cirrhosis undergoing liver transplantation frequently exhibit systemic inflammation, coagulation derangements, and edema, indicating endothelial dysfunction. This syndrome may worsen after ischemia–reperfusion injury of th
Externí odkaz:
https://doaj.org/article/feee8bd280834503980a25c76572192c
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 5, Pp n/a-n/a (2024)
Abstract Microvesicles (MVs) are a subtype of extracellular vesicles that can transfer biological information from their producer cells to target cells. This communication can in turn affect both normal and pathological processes. Mounting evidence h
Externí odkaz:
https://doaj.org/article/b01f1e53e9ef4fe3b04b9f2a298c39cb
Autor:
Fengjiao Wu, Yuhong Han, Qianqian Xiong, Haitao Tang, Jing Shi, Qingqing Yang, Xuemeng Li, Haoxuan Jia, Jun Qian, Yishu Dong, Tuantuan Li, Yong Gao, Zhongqing Qian, Hongtao Wang, Ting Wang
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1536 (2024)
Septic encephalopathy (SE) represents a severe inflammatory syndrome linked to elevated septic mortality rates, lacking specific therapeutic interventions, and often resulting in enduring neurological sequelae. The present investigation endeavors to
Externí odkaz:
https://doaj.org/article/b417a0fa8f7d48b9b22a39a92ec8b4bc
Autor:
Gustavo Falero-Diaz, Catarina de A. Barboza, Roberto I. Vazquez-Padron, Omaida C. Velazquez, Roberta M. Lassance-Soares
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1358 (2024)
Background: Critical limb ischemia (CLI) is the end stage of peripheral artery disease (PAD), and around 30% of CLI patients are ineligible for current treatments. The angiogenic benefits of c-Kit have been reported in the ischemia scenario; however,
Externí odkaz:
https://doaj.org/article/64ab020aed6245b7a5df7eaf95e1b7ab
Autor:
Radosław Bednarek, Dagmara W. Wojkowska, Marcin Braun, Cezary Watala, Moro O. Salifu, Maria Swiatkowska, Anna Babinska
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-19 (2023)
Abstract Background The F11R/JAM-A cell adhesion protein was examined as the therapeutic target in triple negative breast cancer (TNBC) with the use of the peptide antagonist to F11R/JAM-A, that previously inhibited the early stages of breast cancer
Externí odkaz:
https://doaj.org/article/bbdd0686426b489e9d291f4e462a93e0