Zobrazeno 1 - 10
of 122
pro vyhledávání: '"endocrine cancers"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPI3K/AKT signaling pathway is upregulated in a broad spectrum of cancers. Among the class I PI3Ks (PI3Kδ/β/δ isoforms), PI3Kδ has been implicated in hematologic cancers and solid tumors. Alternative splicing is a post-transcriptional
Externí odkaz:
https://doaj.org/article/1eae200900df4889b34fd432d1944e28
Akademický článek
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Autor:
Roland Därr, Jonas Kater, Peggy Sekula, Birke Bausch, Tobias Krauss, Christoph Bode, Gerd Walz, Hartmut P Neumann, Stefan Zschiedrich
Publikováno v:
Endocrine Connections, Vol 9, Iss 8, Pp 834-844 (2020)
The optimal treatment strategy for patients with small non-functioning VHL-related incidentalomas is unclear. We searched the Freiburg VHL registry for patients with radiologic evidence of pheochromocytoma/paraganglioma (PHEO/PGL). In total, 176 pati
Externí odkaz:
https://doaj.org/article/292ad279a5a94b12a1f6b9a78cbc0872
Autor:
Linus D. Kloker, Susanne Berchtold, Irina Smirnow, Julia Beil, Andreas Krieg, Bence Sipos, Ulrich M. Lauer
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Oncolytic virotherapy is an upcoming treatment option for many tumor entities. But so far, a first oncolytic virus only was approved for advanced stages of malignant melanomas. Neuroendocrine tumors (NETs) constitute a heterogenou
Externí odkaz:
https://doaj.org/article/7feb99fdfa9c48e58f33df3aadf9220f
Autor:
Raziyeh Abooshahab, Hamidreza Ardalani, Maryam Zarkesh, Koroush Hooshmand, Ali Bakhshi, Crispin R. Dass, Mehdi Hedayati
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1154 (2022)
Clinical endocrinology entails an understanding of the mechanisms involved in the regulation of tumors that occur in the endocrine system. The exact cause of endocrine cancers remains an enigma, especially when discriminating malignant lesions from b
Externí odkaz:
https://doaj.org/article/aa8828746b26441aa27dbb34a0adf88d
Autor:
Nassim Ghaffari-Tabrizi-Wizsy, Christina Angelika Passegger, Laura Nebel, Fabian Krismer, Gudrun Herzer-Schneidhofer, Gert Schwach, Roswitha Pfragner
Publikováno v:
Endocrine Connections, Vol 8, Iss 5, Pp 462-467 (2019)
Preclinical trials of medullary thyroid cancer (MTC) therapeutics require both in vitro and in vivo analyses. Human tumour xenografted rodent models, which are considered the ‘gold standard’ to study and validate the efficacy and toxicity of lead
Externí odkaz:
https://doaj.org/article/8d4ebc8d5a3c450291df91b44c20cba3
Replication of newly proposed TNM staging system for medullary thyroid carcinoma: a nationwide study
Autor:
Jes Sloth Mathiesen, Jens Peter Kroustrup, Peter Vestergaard, Per Løgstrup Poulsen, Åse Krogh Rasmussen, Ulla Feldt-Rasmussen, Sten Schytte, Stefano Christian Londero, Henrik Baymler Pedersen, Christoffer Holst Hahn, Jens Bentzen, Sören Möller, Mette Gaustadnes, Maria Rossing, Finn Cilius Nielsen, Kim Brixen, Christian Godballe
Publikováno v:
Endocrine Connections, Vol 8, Iss 1, Pp 1-7 (2019)
A recent study proposed new TNM groupings for better survival discrimination among stage groups for medullary thyroid carcinoma (MTC) and validated these groupings in a population-based cohort in the United States. However, it is unknown how well the
Externí odkaz:
https://doaj.org/article/11334d545d344aeda93d348564e86715
Publikováno v:
Endocrine Connections, Vol 7, Iss 1, Pp 47-55 (2017)
Poorly differentiated thyroid carcinoma (PDTC) is a rare malignancy with higher mortality than well-differentiated thyroid carcinoma. The histological diagnosis can be difficult as well as the therapy. Improved diagnosis and new targeted therapies re
Externí odkaz:
https://doaj.org/article/8899b1ae495d4406ab81b76df394dc5f
Autor:
Logan Mills, Panagiotis Drymousis, Yogesh Vashist, Christoph Burdelski, Andreas Prachalias, Parthi Srinivasan, Krishna Menon, Corina Cotoi, Saboor Khan, Judith Cave, Thomas Armstrong, Martin O Weickert, Jakob Izbicki, Joerg Schrader, Andreja Frilling, John K Ramage, Raj Srirajaskanthan
Publikováno v:
Endocrine Connections, Vol 6, Iss 8, Pp 876-885 (2017)
Small non-functioning pancreatic NETs (pNETs) ≤2 cm can pose a management dilemma in terms of surveillance or resection. There is evidence to suggest that a surveillance approach can be considered since there are no significant radiological changes
Externí odkaz:
https://doaj.org/article/746efdc1a29f4353a7e522c3650808c0
Autor:
T P McVeigh, R J Mulligan, U M McVeigh, P W Owens, M Bell, F Sebag, C Guerin, D S Quill, J B Weidhaas, M J Kerin, A J Lowery
Publikováno v:
Endocrine Connections, Vol 6, Iss 8, Pp 614-624 (2017)
Introduction: MicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA). Polymorphisms in genes encoding miRNAs or in miRNA–
Externí odkaz:
https://doaj.org/article/80e3b8915e7b40ddbf9f6bfa1c52a131