Zobrazeno 1 - 10
of 1 713
pro vyhledávání: '"endochondral bone"'
Publikováno v:
European Cells & Materials, Vol 47, Pp 219-237 (2024)
Fracture healing is a complex event that involves the coordination of various different processes, including intramembranous and endochondral bone formation. When facing fracture nonunion or delayed union, few organizational engineering structures ca
Externí odkaz:
https://doaj.org/article/8d2587089c36471bafa630f880f0dc71
Autor:
Pengzhen Cheng, Xueyi Zhao, Meige Han, Yaping Zhuang, Fenru Ning, Yaqian Hu, Weiguang Lu, Sheng Miao, Chengxiang Zhao, Liyuan Jia, Xue Hao, Meng Sun, Junxiang Wang, Fulin Chen, Liu Yang, Qiang Jie
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: Developmental engineering based on endochondral ossification has been proposed as a potential strategy for repairing of critical bone defects. Bone development is driven by growth plate-mediated endochondral ossification. Under physiolo
Externí odkaz:
https://doaj.org/article/033b889a11564c54b4bdad7566e40edd
Publikováno v:
生物医学转化, Vol 4, Iss 4, Pp 2-9-16 (2023)
Fracture healing is a multifactorial process. Most fractures are healed by the process of endochondral ossification, involving the formation of a cartilaginous soft callus and the process of cartilage-tobone transition. Hypertrophic chondrocytes have
Externí odkaz:
https://doaj.org/article/46d70039665e49d49cf534787bfd198f
Publikováno v:
JBMR Plus, Vol 7, Iss 12, Pp n/a-n/a (2023)
ABSTRACT GαS, the stimulatory G protein α‐subunit that raises intracellular cAMP levels by activating adenylyl cyclase, plays a vital role in bone development, maintenance, and remodeling. Previously, using transgenic mice overexpressing GαS in
Externí odkaz:
https://doaj.org/article/1158354f8bc44884a0960d6e7e525694
Akademický článek
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Autor:
Xi Liu, Fan Qian, Qiwei Fan, Li Lin, Meiyao He, Peizhi Li, Hongmei Cai, Lisha Ma, Xin Cheng, Xuesong Yang
Publikováno v:
Journal of Orthopaedic Translation, Vol 31, Iss , Pp 52-61 (2021)
Background: Diabetes mellitus could cause numerous complications and health problems including abnormality of endochondral bone formation during embryogenesis. However, the underlying mechanisms still remain obscure. Methods: Streptozotoci (STZ) was
Externí odkaz:
https://doaj.org/article/c6d424e094e0452ebf705f048e3b92c7
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101616- (2022)
Endochondral bone formation is an important pathway in fracture healing, involving the formation of a cartilaginous soft callus and the process of cartilage-to-bone transition. Failure or delay in the cartilage-to-bone transition causes an impaired b
Externí odkaz:
https://doaj.org/article/556166da799440b58d4139aee00c47b4
Autor:
Yasamin Hadaegh, Tarek H. El-Bialy
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108185- (2022)
Mandibular condyle (MC) in postnatal life, grows mainly by endochondral bone growth which is a multistep process and the condylar cartilage plays a vital role in its regional adaptive growth. Hence, for determining the exact effect of a treatment suc
Externí odkaz:
https://doaj.org/article/a540f8f380a545c796aa300a081400d1
Autor:
Daisuke Tateiwa, Takashi Kaito, Kunihiko Hashimoto, Rintaro Okada, Joe Kodama, Junichi Kushioka, Zeynep Bal, Hiroyuki Tsukazaki, Shinichi Nakagawa, Yuichiro Ukon, Hiromasa Hirai, Hongying Tian, Ivan Alferiev, Michael Chorny, Satoru Otsuru, Seiji Okada, Masahiro Iwamoto
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Bone morphogenetic proteins (BMPs) have been clinically applied for induction of bone formation in musculoskeletal disorders such as critical-sized bone defects, nonunions, and spinal fusion surgeries. However, the use of supraphysiological doses of
Externí odkaz:
https://doaj.org/article/cdcc23b661c84c68831b00771c017cd4
Autor:
Alessia Longoni, Lizette Utomo, Abbie Robinson, Riccardo Levato, Antoine J. W. P. Rosenberg, Debby Gawlitta
Publikováno v:
Advanced Science, Vol 9, Iss 6, Pp n/a-n/a (2022)
Abstract Clinical implementation of endochondral bone regeneration (EBR) would benefit from the engineering of devitalized cartilaginous constructs of allogeneic origins. Nevertheless, development of effective devitalization strategies that preserves
Externí odkaz:
https://doaj.org/article/9f3d8b7740774487bb3ab9c0916df1f5