The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice.

Autor: Favier M; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, H4H 1R3, Canada. mathieu.favier@mail.mcgill.ca., Martin Garcia E; Laboratory of Neuropharmacology-Neurophar, Department of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.; Departament de Psicobiologia i Metodologia de les Ciències de la Salut, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, 08193, Barcelona, Spain., Icick R; Département de Psychiatrie et de Médecine Addictologique, DMU Neurosciences, APHP.Nord, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, F-75010, France.; INSERM U1144, 'Therapeutic optimization in neuropsychopharmacology', Paris, F-75006, France.; Université Paris Cité, Inserm UMR-S1144, Paris, F-75006, France.; Neurobiologie Intégrative des Systèmes Cholinergiques, Département de Neurosciences, Institut Pasteur, Paris, F-75015, France., de Almeida C; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Jehl J; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France.; Brain Plasticity Unit, CNRS UMR 8249, ESPCI Paris, PSL Research University, 75005, Paris, France., Desplanque M; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Zimmermann J; Neurocure NWFZ, Charite Universitaetsmedizin, Institut für Neurophysiologie, Charitéplatz 1, 10117, Berlin, Germany., Henrion A; Fondation FondaMental, Créteil, France.; Université Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, F-94010, Créteil, France., Mansouri-Guilani N; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Mounier C; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, H4H 1R3, Canada., Ribeiro S; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, H4H 1R3, Canada., Henderson F; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Geoffroy A; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Mella S; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Poirel O; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Bernard V; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Fabre V; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., Li Y; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing, China., Rosenmund C; Neurocure NWFZ, Charite Universitaetsmedizin, Institut für Neurophysiologie, Charitéplatz 1, 10117, Berlin, Germany., Jamain S; Fondation FondaMental, Créteil, France.; Université Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, F-94010, Créteil, France., Vorspan F; Département de Psychiatrie et de Médecine Addictologique, DMU Neurosciences, APHP.Nord, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, F-75010, France.; INSERM U1144, 'Therapeutic optimization in neuropsychopharmacology', Paris, F-75006, France.; Université Paris Cité, Inserm UMR-S1144, Paris, F-75006, France., Mourot A; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France.; Brain Plasticity Unit, CNRS UMR 8249, ESPCI Paris, PSL Research University, 75005, Paris, France., Duriez P; GHU Paris Psychiatrie et Neurosciences (CMME, Hospital Sainte-Anne), Institute of Psychiatry and Neuroscience of Paris (INSERM UMR1266), Paris, France., Pinhas L; PHLIP Mental Health and Painless Medicine clinic, Toronto, Canada., Maldonado R; Laboratory of Neuropharmacology-Neurophar, Department of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.; Departament de Psicobiologia i Metodologia de les Ciències de la Salut, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, 08193, Barcelona, Spain., Pietrancosta N; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France.; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des Biomolécules, LBM, 75005, Paris, France.; LCBPT, Université Paris Descartes, Sorbonne Paris Cité, UMR 8601, CNRS, Paris, 75006, France., Daumas S; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France., El Mestikawy S; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, H4H 1R3, Canada. salah.elmestikawy@mcgill.ca.; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine - Institut de Biologie Paris Seine (NPS - IBPS), 75005, Paris, France. salah.elmestikawy@mcgill.ca.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 07; Vol. 15 (1), pp. 5691. Date of Electronic Publication: 2024 Jul 07.

Mice with a genetic loss of vesicular glutamate transporter 3 targeted to 5-hydroxytryptamine neurons show impairments in reward-based learning

Autor: Gullino, L., Jayaram, S., El Mestikawy, S., Bannerman, D., Sharp, T.

Publikováno v: In Neuroscience Applied 2023 2 Supplement 2

VGLUT3 Deletion Rescues Motor Deficits and Neuronal Loss in the zQ175 Mouse Model of Huntington's Disease.

Autor: Ibrahim KS; University of Ottawa Brain and Mind Research Institute.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt., El Mestikawy S; Neuroscience Paris Seine, Institut de Biologie Paris Seine, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Sorbonne Université, 75006, France Paris.; Department of Psychiatry, Douglas Hospital Research Center, McGill University, Montreal, Quebec H4H 1R3, Canada., Abd-Elrahman KS; University of Ottawa Brain and Mind Research Institute.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt., Ferguson SSG; University of Ottawa Brain and Mind Research Institute sferguso@uottawa.ca.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2023 Jun 07; Vol. 43 (23), pp. 4365-4377. Date of Electronic Publication: 2023 Apr 13.

Nanoscopic distribution of VAChT and VGLUT3 in striatal cholinergic varicosities suggests colocalization and segregation of the two transporters in synaptic vesicles.

Autor: Cristofari P; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France., Desplanque M; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France., Poirel O; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France., Hébert A; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France., Dumas S; Oramacell, Paris, France., Herzog E; University of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, IINS, UMR 5297, Bordeaux, France., Danglot L; Université de Paris, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Membrane Traffic in Healthy & Diseased Brain, Paris, France.; Université de Paris, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, NeurImag Imaging Facility, Paris, France.; GHU Paris Psychiatrie & Neurosciences, Paris, France., Geny D; Université de Paris, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, NeurImag Imaging Facility, Paris, France., Gilles JF; Imaging Facility of the Institut de Biologie Paris-Seine (IBPS)-Sorbonne Université, Paris, France., Geeverding A; Sorbonne Université, CNRS, Institut de Biologie Paris-Seine (IBPS), Service de Microscopie Électronique (IBPS-SME), Paris, France., Bolte S; Imaging Facility of the Institut de Biologie Paris-Seine (IBPS)-Sorbonne Université, Paris, France., Canette A; Sorbonne Université, CNRS, Institut de Biologie Paris-Seine (IBPS), Service de Microscopie Électronique (IBPS-SME), Paris, France., Trichet M; Sorbonne Université, CNRS, Institut de Biologie Paris-Seine (IBPS), Service de Microscopie Électronique (IBPS-SME), Paris, France., Fabre V; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France., Daumas S; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France., Pietrancosta N; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France.; Sorbonne Université-CNRS UMR 7203-Laboratoire des BioMolécules, Paris, France., El Mestikawy S; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France.; Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada., Bernard V; Sorbonne Université-CNRS UMR 8246-INSERM U1130-Neuroscience Paris Seine-Institut de Biologie Paris Seine (NPS-IBPS), Paris, France.

Publikováno v: Frontiers in molecular neuroscience [Front Mol Neurosci] 2022 Sep 13; Vol. 15, pp. 991732. Date of Electronic Publication: 2022 Sep 13 (Print Publication: 2022).

Reduced Metabotropic Glutamate Receptor Type 5 Availability in the Epileptogenic Hippocampus: An in vitro Study.

Autor: Zimmermann M; Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.; Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada., Minuzzi L; Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada.; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada., Aliaga Aliaga A; Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada.; PET Unit, McConnell Brain Imaging Centre, Montréal, QC, Canada., Guiot MC; Department of Pathology, Montréal Neurological Institute, Montréal, QC, Canada., Hall JA; Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada., Soucy JP; Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.; PET Unit, McConnell Brain Imaging Centre, Montréal, QC, Canada., Massarweh G; PET Unit, McConnell Brain Imaging Centre, Montréal, QC, Canada., El Mestikawy S; Department of Psychiatry, Douglas Research Institute, McGill University, Montréal, QC, Canada., Rosa-Neto P; Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.; Translational Neuroimaging Laboratory, Douglas Research Institute, McGill University, Montréal, QC, Canada., Kobayashi E; Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.

Publikováno v: Frontiers in neurology [Front Neurol] 2022 Jul 22; Vol. 13, pp. 888479. Date of Electronic Publication: 2022 Jul 22 (Print Publication: 2022).