Heparin-binding EGF-like growth factor via miR-126 controls tumor formation/growth and the proteolytic niche in murine models of colorectal and colitis-associated cancers.

Autor: Salama Y; Division of Stem Cell Dynamics, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.; An-Najah Center for Cancer and Stem Cell Research, Faculty of Medicine and Health Sciences, An-Najah National University, PO Box 7, Nablus, Palestine., Munakata S; Division of Stem Cell Dynamics, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.; Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan., Osada T; Department of Gastroenterology, Juntendo University, Urayasu Hospital, Urayasu, Japan., Takahashi S; Division of Clinical Precision Research Platform, the Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan., Hattori K; Center for Genome and Regenerative Medicine, Juntendo University, Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. khattori@juntendo.ac.jp.; Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. khattori@juntendo.ac.jp., Heissig B; Division of Stem Cell Dynamics, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. heissig@juntendo.ac.jp.; Department of Bioresource Bank, Graduate School of Medicine, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. heissig@juntendo.ac.jp.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 Oct 17; Vol. 15 (10), pp. 753. Date of Electronic Publication: 2024 Oct 17.

The Multiple Functions of HB-EGF in Female Reproduction and Related Cancer: Molecular Mechanisms and Targeting Strategies.

Autor: Zhang Y; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, 99 Zhang Zhidong Road, Wuhan, Hubei, 430060, People's Republic of China., Tang L; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, 99 Zhang Zhidong Road, Wuhan, Hubei, 430060, People's Republic of China., Liu H; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, 99 Zhang Zhidong Road, Wuhan, Hubei, 430060, People's Republic of China. liuhua008@tom.com., Cheng Y; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, 99 Zhang Zhidong Road, Wuhan, Hubei, 430060, People's Republic of China. yanxiangCheng@whu.edu.cn.

Publikováno v: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2024 Sep; Vol. 31 (9), pp. 2588-2603. Date of Electronic Publication: 2024 Feb 29.

Novel IL-4/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury.

Autor: Yang Y; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Xu L; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Atkins C; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Kuhlman L; The University of Texas Health Science Center at Houston, Houston, TX, USA., Zhao J; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Jeong JM; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Wen Y; The University of Texas Health Science Center at Houston, Houston, TX, USA., Moreno N; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Kim KH; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., An YA; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Wang F; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Bynon S; Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Villani V; Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Gao B; Laboratory of Liver Disease, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, USA., Brombacher F; University of Cape Town Faculty of Health Sciences, Observatory, Western Cape, South Africa., Harris R; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Eltzschig HK; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Jacobsen E; Division of Allergy, Asthma and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, AZ, USA., Ju C; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA changqing.ju@uth.tmc.edu.

Publikováno v: Gut [Gut] 2024 Aug 08; Vol. 73 (9), pp. 1543-1553. Date of Electronic Publication: 2024 Aug 08.

HB-EGF-loaded nanovesicles enhance trophectodermal spheroid attachment and invasion.

Autor: Poh QH; Molecular Proteomics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Department of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe University, Bundoora, Victoria, Australia.; Department of Cardiovascular Research, Translation and Implementation, La Trobe University, Melbourne, Victoria, Australia., Rai A; Molecular Proteomics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Department of Cardiovascular Research, Translation and Implementation, La Trobe University, Melbourne, Victoria, Australia.; Central Clinical School, Monash University, Melbourne, Victoria, Australia., Cross J; Molecular Proteomics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Greening DW; Molecular Proteomics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Department of Cardiovascular Research, Translation and Implementation, La Trobe University, Melbourne, Victoria, Australia.; Central Clinical School, Monash University, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, University of Melbourne, Melbourne, Victoria, Australia.

Publikováno v: Proteomics [Proteomics] 2024 Jun; Vol. 24 (11), pp. e2200145. Date of Electronic Publication: 2024 Jan 12.

HB-EGF promotes progenitor cell proliferation and sensory neuron regeneration in the zebrafish olfactory epithelium.

Autor: Sireci S; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Kocagöz Y; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Alkiraz AS; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Güler K; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Dokuzluoglu Z; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Balcioglu E; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Meydanli S; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Demirler MC; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye., Erdogan NS; Kadir Has University, Core Program, Istanbul, Türkiye., Fuss SH; Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogaziçi University, Istanbul, Türkiye.

Publikováno v: The FEBS journal [FEBS J] 2024 May; Vol. 291 (10), pp. 2098-2133. Date of Electronic Publication: 2023 Dec 20.